MARCO 抗体 (AA 420-431)
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- 抗原 See all MARCO 抗体
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
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抗原表位
- AA 420-431
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适用
- 人, Cow
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MARCO antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- 特异性
- This antibody binds specifically to MARCO (recognizes domain V between residues 420 and 431), and has been shown to partially block ligand binding.
- 无交叉反应
- 小鸡
- 交叉反应 （详细）
- Species reactivity (tested):Human, Bovine.
- 纯化方法
- Protein G Chromatography
- 免疫原
- Human alveolar macrophages
- 克隆位点
- PLK-1
- 亚型
- IgG3
- Top Product
- Discover our top product MARCO Primary Antibody
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anti-Macrophage Receptor with Collagenous Structure (MARCO) (AA 367-519) antibody
MARCO 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Receptor with Collagenous Structure (MARCO) (AA 421-520) antibodyMARCO 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Receptor with Collagenous Structure (MARCO) (AA 13-40) antibodyMARCO 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24662 unconjugated
anti-Macrophage Receptor with Collagenous Structure (MARCO) (AA 366-518) antibodyMARCO 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Receptor with Collagenous Structure (MARCO) antibodyMARCO 适用: 人 WB, IP, IF, FACS, IHC (fro) 宿主: 兔 Chimeric PLK1 unconjugated Recombinant Antibody
anti-Macrophage Receptor with Collagenous Structure (MARCO) (AA 370-419) antibodyMARCO 适用: 人, 小鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Receptor with Collagenous Structure (MARCO) (AA 71-120) antibodyMARCO 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Receptor with Collagenous Structure (MARCO) (N-Term) antibodyMARCO 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Receptor with Collagenous Structure (MARCO) (C-Term) antibodyMARCO 适用: 人, 小鼠, 大鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.1 % BSA
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 2-8 °C.
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- 抗原
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
- 别名
- MARCO (MARCO 产品)
- 别名
- AI323439 antibody, Ly112 antibody, Scara2 antibody, SCARA2 antibody, macrophage receptor with collagenous structure antibody, MARCO antibody, Marco antibody
- 背景
- The scavenger receptors (SRs) expressed by macrophages are thought to play an important role in the immune response against bacteria by mediating ligand binding and phagocytosis. SRs can be divided into three different classes based upon their structural properties, which are termed SR-A, SR-B and SR-C. SRs-A are homotrimeric glycoproteins composed of 77 kDa monomers subdivided into 3 types.. The molecular structure of MARCO resembles that of SR-A type I, containing a triple-helical collagenous domain and a scavenger receptor cysteine-rich (SRCR) domain at the C terminus. MARCO is only expressed in some subpopulations of macrophages, although it's expression can be strongly upregulated during infection or LPS treatment. Furthermore, MARCO is, like sinusoidal endothelial cell markers DC-SIGNR, LYVE-1 and stabilin-2, expressed by sinusoidal endothelial cells in lymph node. MARCO expressed by alveolar macrophages seems to play an important role in response to inhaled particles and airborne pathogens.Synonyms: Scavenger Receptor, macrophage receptor with collagenous structure
- 基因ID
- 8685
- NCBI登录号
- NP_006761
- UniProt
- Q9UEW3
- 途径
- Activation of Innate immune Response
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