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MBP/MBL 抗体

MBP/MBL 适用: 小鼠 WB, EIA 宿主: 大鼠 Monoclonal 16A8 unconjugated
产品编号 ABIN1108116
发货至: 中国
  • 抗原 See all MBP/MBL 抗体
    MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))
    适用
    • 8
    • 2
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 6
    • 2
    • 1
    大鼠
    克隆类型
    • 7
    • 2
    单克隆
    标记
    • 7
    • 2
    This MBP/MBL antibody is un-conjugated
    应用范围
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Mouse
    纯化方法
    Protein G
    克隆位点
    16A8
    亚型
    IgG2a
    Top Product
    Discover our top product MBP/MBL Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))
    别名
    Mannan Binding Protein (MBP/MBL 产品)
    别名
    COLEC1 antibody, HSMBPC antibody, MBL antibody, MBL2D antibody, MBP antibody, MBP-C antibody, MBP1 antibody, MBPD antibody, pMBP-27 antibody, MBL1 antibody, cMBl antibody, collectin antibody, L-MBP antibody, MBL-C antibody, RaRF p28A antibody, mbl antibody, mannose binding lectin 2 antibody, mannose-binding lectin (protein C) 2 antibody, mannose-binding protein C-like antibody, MBL2 antibody, Mbl2 antibody, LOC100911854 antibody
    背景
    Mannose Binding Lectin (MBL) also called mannose- or mannan-binding protein (MBP) is a member of the group of collectins. MBL is an oligomeric lectin that recognizes carbohydrates as mannose and N-acetylglucosamine on pathogens. MBL contains a cysteine rich, a collagen like and a carbohydrate recognition domain. It forms a complex with C1r/C1s like serine proteases designated MASPs that proteolytically cleave C4, C2 and C3. MBL is able to activate the complement pathway independent of the classical and alternative complement activation pathways. The MBL-MASP pathway (better known as the lectin pathway) is antibody and C1q-independent. MBL exhibits complement-dependent antibacterial activity and acts directly as an opsonic and therefore plays an important role in innate immunity. MBL is synthesized by hepatocytes and has been isolated from the liver or serum of several vertebrate species. Only one form of human MBL has been characterized, while two forms are found in rhesus monkeys, rabbits, rats and mice. The mouse forms are known as MBL-A and MBL-C. The MBL-C concentrations in serum are about 6-fold compared to that of MBL-A. MBL-A, but not MBL-C was found to be an acute phase protein in casein and LPS-injection models. MBL-C exists in higher oligomeric forms than MBL-A.Synonyms: MBL, MBL2, MBP, MBP-C, MBP1, Mannan-binding protein, Mannose-binding lectin, Mannose-binding protein C
    基因ID
    10090
    UniProt
    P41317
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