LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) 抗体

ABIN1108043 产品详细信息, 供应商: Log in to see
抗原
  • PINCH
  • PINCH-1
  • PINCH1
  • Pinch1
  • RGD1560732
  • LIMS3
  • LIMS3L
  • 2310016J22Rik
  • 4921524A02Rik
  • AI507642
  • AU021743
  • AW551584
  • C430041B13Rik
  • Lims1l
  • LIM and senescent cell antigen-like domains 1
  • LIMS1
  • Lims1
适用

53
32
32
5
4
4
4
4
4
3
3
2
2
2
宿主
小鼠
43
11
克隆类型 (克隆位点)
单克隆 ()
标记
非结合性
2
2
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
38
19
13
13
9
8
6
5
3
1
1
选项
Supplier
Log in to see
Supplier Product No.
Log in to see
克隆位点 5G7
亚型 IgG1
特异性 This antibody reacts to PINCH.
交叉反应 (详细) Species reactivity (tested):Human.
纯化方法 Ascites
别名 LIMS1 (LIMS1 Antibody 摘要)
背景 The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.Synonyms: LIM and senescent cell antigen-like-containing domain protein 1, LIMS-1, PINCH, PINCH-1, PINCH1, Particularly interesting new Cys-His protein 1, Renal carcinoma antigen NY-REN-48
分子量 37 kDa
基因ID 3987
研究领域 Cancer, Angiogenesis
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用
状态 Liquid
厂商提供的图像
Flow Cytometry (FACS) image for anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibody (ABIN1108043) anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibody
Immunofluorescence (IF) image for anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibody (ABIN1108043) anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibody (Image 2)
Western Blotting (WB) image for anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibody (ABIN1108043) anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibody (Image 3)
Western Blotting (WB) image for anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibody (ABIN1108043) anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibody (Image 4)
ELISA image for anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibody (ABIN1108043) anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibody (Image 5)
背景 Yang, Wang, Hawkins, Chen, Vaynberg, Mao, Tu, Zuo, Wang, Wang, Wu, Tjandra, Qin: "Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5836-44, 2009 (PubMed).

Chiswell, Zhang, Murphy, Boggon, Calderwood: "The structural basis of integrin-linked kinase-PINCH interactions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 52, pp. 20677-82, 2008 (PubMed).

您还需要查找其他产品吗?