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IL-4 抗体 (PE)

IL4 适用: 人 FACS 宿主: 小鼠 Monoclonal 8F-12 PE
产品编号 ABIN1107850
发货至: 中国
  • 抗原 See all IL-4 (IL4) 抗体
    IL-4 (IL4) (Interleukin 4 (IL4))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This IL-4 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The antibody detects human Interleukin 4, which is a 14 kDa molecular weight glycoprotein. Other species not tested.
    纯化方法
    Affinity chromatography
    克隆位点
    8F-12
    亚型
    IgG1
    Top Product
    Discover our top product IL4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
  • 抗原
    IL-4 (IL4) (Interleukin 4 (IL4))
    别名
    Interleukin-4 / IL4 (IL4 产品)
    别名
    IL4 antibody, IL-4 antibody, BCGF-1 antibody, BCGF1 antibody, BSF-1 antibody, BSF1 antibody, Il-4 antibody, Il4e12 antibody, IL2 antibody, interleukin 4 antibody, IL4 antibody, Il4 antibody
    背景
    The immune system reacts to a pathogen by activation of balanced network of the humoral and cellular immune responses. Subsequently the activated condition of the immune system will, after the elimination of the pathogen, be down-regulated to a balanced situation again. Control of the immune response requires efficient communication between the different cells involved in this response. This interaction is provided by cell/cell contact and by a complex array of mediators. Among these mediators cytokines, soluble factors produced by these cells, play an important role. Cytokines can act on other cells locally or distantly, but can be even auto regulating. Cytokines can behave stimulatory or inhibitory, or can even perform both activities, depending on the (pre)activation stage of the target cell. (3, 4) Interleukine 4 (IL-4) is a cytokine expressed by activated T cells, mast cells and bone marrow stromal cells. Originally, IL-4 was referred to as the B cell differentiation factor, B cell growth factor 1 or B cell stimulatory factor 1. The function of IL-4 is pleiotropic, i.e. stimulation, proliferation induction, and modulation of target cell functions. These target cells include B cells, but also T cells, NK and LAK cells, as well as antigen-processing cells like monocytes and macrophages.Synonyms: B-cell stimulatory factor 1, BSF1, Binetrakin, IL-4, Lymphocyte stimulatory factor 1, Pitrakinra
    基因ID
    3565
    NCBI登录号
    NP_000580
    UniProt
    P05112
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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