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SEMA7A 抗体

SEMA7A 适用: 人 WB, IP, FACS 宿主: 小鼠 Monoclonal MEM-150 unconjugated
产品编号 ABIN110773
发货至: 中国
  • 抗原 See all SEMA7A 抗体
    SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This SEMA7A antibody is un-conjugated
    应用范围
    • 43
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    Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)
    特异性
    The antibody reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored glycoprotein expressed on various cell types including erythrocytes, lymphoblasts, at low levels it is present on circulating lymphocytes.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Ion exchange chromatography
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    HPB-ALL human T cell line
    克隆位点
    MEM-150
    亚型
    IgM
    Top Product
    Discover our top product SEMA7A Primary Antibody
  • 应用备注
    Flow Cytometry. Immunoprecipitation. Western Blotting under non reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. Dilute only prior to immediate use
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
    别名
    CD108 / SEMA7A (SEMA7A 产品)
    别名
    2900057C09Rik antibody, CDw108 antibody, H-Sema-L antibody, M-Sema-L antibody, Semal antibody, CD108 antibody, H-SEMA-K1 antibody, JMH antibody, SEMAK1 antibody, SEMAL antibody, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A antibody, semaphorin 7A (John Milton Hagen blood group) antibody, Sema7a antibody, SEMA7A antibody
    背景
    CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors plexin C1 and b1 integrins.Synonyms: JMH blood group antigen, John-Milton-Hargen human blood group Ag, SEMAL, Semaphorin-7A, Semaphorin-K1, Semaphorin-L
    基因ID
    8482
    NCBI登录号
    NP_001139501
    UniProt
    O75326
    途径
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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