-
- 抗原 See all HSPD1 抗体
- HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
-
适用
- 人, 大鼠, 小鸡
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This HSPD1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody reacts to HSP60.
- 纯化方法
- Affinity chromatography
- 免疫原
- Recombinant human heat shock protein 60 (HSP60)
- 克隆位点
- SJ-60
- 亚型
- IgG1
- Top Product
- Discover our top product HSPD1 Primary Antibody
-
anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 501-573) antibody
HSPD1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) antibodyHSPD1 适用: 人 WB, IHC, FACS, ELISA, IP 宿主: 小鼠 Monoclonal LK1 unconjugated
anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) antibodyHSPD1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) antibodyHSPD1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IEM 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 172-343) antibodyHSPD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 1-573) antibodyHSPD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 316-573) antibodyHSPD1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 1-573) antibodyHSPD1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) antibodyHSPD1 适用: 人, 小鼠, 大鼠, 小鸡, 猴, 犬, Hamster, Cow, 兔, Pig, 绵羊, Drosophila melanogaster, 非洲爪蟾 WB, IHC, FACS, IF, ISt, StM 宿主: 小鼠 Monoclonal LK1 unconjugated
anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 340-374) antibodyHSPD1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB55969 unconjugated
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 溶解方式
- Restore with 1.2 % sodium acetate or neutral PBS
- 浓度
- 0,1 mg/mL
- 缓冲液
- 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
- 别名
- HSP60 (HSPD1 产品)
- 别名
- CPN60 antibody, GROEL antibody, HLD4 antibody, HSP-60 antibody, HSP60 antibody, HSP65 antibody, HuCHA60 antibody, SPG13 antibody, chaperonin antibody, cpn60 antibody, groel antibody, hld4 antibody, hsp60 antibody, hsp65 antibody, spg13 antibody, 60kDa antibody, Hsp60 antibody, 12 antibody, BP5 antibody, CG12101 antibody, Cpn60 antibody, Dmel\\CG12101 antibody, Dmhsp60 antibody, G62 antibody, HSP60A antibody, Hsp60A antibody, IEF16 antibody, Mmp-P1 antibody, SSP 7506 antibody, d-hsp60 antibody, hsp60A antibody, l(1)10Ac antibody, l(1)BP5 antibody, l(1)G8 antibody, l(1)HM21 antibody, l(1)L12 antibody, l(1)dp025 antibody, cb863 antibody, fa04a05 antibody, fb22d10 antibody, fi27b05 antibody, id:ibd2197 antibody, sb:cb144 antibody, wu:fa04a05 antibody, wu:fb22d10 antibody, wu:fi04a12 antibody, wu:fi27b05 antibody, MIF4 antibody, MNA2 antibody, mopA antibody, groL antibody, crpA antibody, Hspd1-30p antibody, heat shock protein family D (Hsp60) member 1 antibody, heat shock protein family D (Hsp60) member 1 S homeolog antibody, 60 kDa heat shock protein, mitochondrial antibody, heat shock protein 1 (chaperonin) antibody, Heat shock protein 60A antibody, heat shock 60 protein 1 antibody, chaperone ATPase HSP60 antibody, molecular chaperone GroEL antibody, thermosome subunit antibody, chaperonin GroEL antibody, mitochondrial chaperonin antibody, heat shock protein family D member 1 antibody, HSPD1 antibody, hspd1.S antibody, hspd1 antibody, LOC100414401 antibody, Hspd1 antibody, Hsp60A antibody, HSP60 antibody, groEL antibody, MMP_RS07785 antibody, groEl antibody, LOC100136430 antibody
- 背景
- Heat shock 60KD protein (HSP60) is a member of the chaperonin class of protein factors, which include the Escherichia coli groEL protein and the Rubisco subunit-binding protein of chloroplasts. It acts as a costimulator of human regulatory CD4-positive/CD25 -positive T cells, which inhibit lymphoproliferation and IFNG and TNFsecretion by CD4-positive and CD8-positive T cells. HSP60 enhances Treg activity via TLR2, leading to activation of an intracellular signaling cascade that included p38, as well as inhibition of ERK phosphorylation. Suppression of target T cells is mediated by both cell-to-cell contact and by secretion of TGFB and IL10, and it leads to downregulation of ERK, NFKB, and TBET expression. The self-molecule HSP60 can downregulate adaptive immune responses by upregulating Tregs through TLR2 signaling.Synonyms: 60 kDa chaperonin, 60 kDa heat shock protein mitochondrial, CPN60, Chaperonin 60, GROEL, GroEL Homolog, HSP-60, HSPD1, Heat shock protein 60, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein
- 基因ID
- 3329
- NCBI登录号
- NP_002147
- UniProt
- P10809
- 途径
- Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
-
You are here:
