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Cyclin B1 抗体

CCNB1 适用: 人, 小鼠 IP 宿主: 小鼠 Monoclonal V92-1 unconjugated
产品编号 ABIN1106867
发货至: 中国
  • 抗原 See all Cyclin B1 (CCNB1) 抗体
    Cyclin B1 (CCNB1)
    适用
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    人, 小鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Cyclin B1 antibody is un-conjugated
    应用范围
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    Immunoprecipitation (IP)
    特异性
    This antibody immunoprecipitates Cyclin B1 (55 kDa).
    纯化方法
    Protein-A Agarose Chromatography of hybridoma supernatant.
    免疫原
    Hamster recombinant Cyclin B1.
    克隆位点
    V92-1
    亚型
    IgG1
    Top Product
    Discover our top product CCNB1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2 containing 50 % Glycerol without preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    Cyclin B1 (CCNB1)
    别名
    Cyclin B1 (CCNB1 产品)
    别名
    ccnb antibody, cycb antibody, cb267 antibody, cycb1 antibody, wu:fa19g04 antibody, wu:fb16d01 antibody, wu:fb16e07 antibody, wu:fi21c01 antibody, ccnb1 antibody, MGC53596 antibody, CCNB antibody, Ccnb1-rs1 antibody, Ccnb1-rs13 antibody, CycB1 antibody, Cycb-4 antibody, Cycb-5 antibody, Cycb1-rs1 antibody, cyclin B1 antibody, cyclin B1 S homeolog antibody, ccnb1 antibody, ccnb1.2 antibody, ccnb1.S antibody, CCNB1 antibody, Ccnb1 antibody, ccnb1.2.S antibody
    背景
    Cyclins are evolutionarily conserved regulatory proteins that are essential for controlling the progression of the cell-cycle. Proliferating cells express both cyclin B1 and cyclin B2, expression is normally low in G0/G1, increases in S, and is maximal during the G2/M phase of cell division. Cyclin B1 can be found both on intracellular membranes and free in the cytoplasm, in contrast to cyclin B2, which is membrane-associated. Cyclin B1 binds to p34Cdc2, also known as Cdk1, a cyclin-dependent kinase, to form an inactive complex that accumulates in the cytoplasm. Dephosphorylation by Cdc25 results in activation of the complex and translocation to the nucleus. Cyclin B1 is rapidly degraded at the end of mitosis, and this degradation is essential for cells to exit from mitosis.Synonyms: CCNB, CCNB1, Cyclin-B1, G2/mitotic-specific cyclin-B1
    基因ID
    891
    NCBI登录号
    NP_114172
    UniProt
    P14635
    途径
    Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
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