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MBP 抗体 (N-Term)

MBP 适用: 人, Cow, Pig, 兔, 豚鼠, 绵羊 IHC (p), EIA, RIA 宿主: 小鼠 Monoclonal V-h5 unconjugated
产品编号 ABIN110680
发货至: 中国
  • 抗原 See all MBP 抗体
    MBP (Myelin Basic Protein (MBP))
    抗原表位
    • 22
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-118, AA 45-91, N-Term
    适用
    • 113
    • 34
    • 33
    • 18
    • 10
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, Cow, Pig, 兔, 豚鼠, 绵羊
    宿主
    • 81
    • 32
    • 10
    • 4
    • 1
    • 1
    • 1
    小鼠
    克隆类型
    • 85
    • 43
    单克隆
    标记
    • 86
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBP antibody is un-conjugated
    应用范围
    • 84
    • 46
    • 46
    • 15
    • 14
    • 14
    • 11
    • 9
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)
    特异性
    Recognises predominantly residues 45-91.
    交叉反应 (详细)
    Species reactivity (expected):Guinea Pig, Rabbit, Porcine, Bovine, Sheep.
    Species reactivity (tested):Human.
    纯化方法
    Protein A chromatography
    免疫原
    Synthetic peptide corresponding to the amino acids 45-91 of the native molecule conjugated to Bovine Serum Albumin. N-terminal fragment of human MBP (residues 1-118) produced by BNPS-skatole cleavage of pure Human MBP, injected coupled to BSA using carbodiimide.
    克隆位点
    V-h5
    亚型
    IgG1
    Top Product
    Discover our top product MBP Primary Antibody
  • 应用备注
    ELISA. Radioimmunoassays. Immunohistochemistry on Paraffin Sections (10 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS buffer, pH 7.2 containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MBP (Myelin Basic Protein (MBP))
    别名
    Myelin Basic Protein (MBP 产品)
    别名
    C76307 antibody, Hmbpr antibody, R75289 antibody, golli-mbp antibody, mld antibody, shi antibody, Mbps antibody, cb274 antibody, fj33b11 antibody, mbp antibody, wu:fj33b11 antibody, wu:fq15b02 antibody, zgc:136630 antibody, MGC115135 antibody, myelin basic protein antibody, myelin basic protein a antibody, myelin basic protein L homeolog antibody, MBP antibody, Mbp antibody, mbpa antibody, mbp antibody, mbp.L antibody
    背景
    The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.Synonyms: MBP, Myelin membrane encephalitogenic protein
    基因ID
    4155
    NCBI登录号
    NP_001020252
    UniProt
    P02686
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