电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

TLR1 抗体 (FITC)

TLR1 适用: 人 FACS, IF, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal GD2-F4 FITC
产品编号 ABIN1106188
发货至: 中国
  • 抗原 See all TLR1 抗体
    TLR1 (Toll-Like Receptor 1 (TLR1))
    适用
    • 73
    • 49
    • 29
    • 4
    • 4
    • 1
    宿主
    • 73
    • 14
    • 2
    小鼠
    克隆类型
    • 76
    • 13
    单克隆
    标记
    • 37
    • 13
    • 10
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR1 antibody is conjugated to FITC
    应用范围
    • 69
    • 36
    • 32
    • 29
    • 14
    • 13
    • 13
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein G
    免疫原
    TLR1Fc
    克隆位点
    GD2-F4
    亚型
    IgG1
    Top Product
    Discover our top product TLR1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 1 % bovine serum albumin
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    TLR1 (Toll-Like Receptor 1 (TLR1))
    别名
    CD281 / TLR1 (TLR1 产品)
    别名
    CD281 antibody, TIL antibody, TIL. LPRS5 antibody, rsc786 antibody, toll like receptor 1 antibody, toll-like receptor 1 antibody, TLR1 antibody, Tlr1 antibody
    背景
    Toll-like receptors (TLR) are highly conserved throughout evolution and play an essential role in recognizing conserved motifs found in various pathogens and initiating an appropriate innate immune response. In human, ten members of the TLR family have been identified as type I transmembrane signaling receptors containing multiple copies of leucine rich repeats in the extracellular domain and an interleukin-1 (IL-1) receptor motif in the cytoplasmic domain. Mammalian responsiveness to microbial products may be mediated by combinations of TLRs, for example a co-operative effect is observed between TLR1 and TLR2 in response to bacterial lipoproteins. On the other hand, TLR 1 was shown to have the capacity to abrogate TLR4 signaling. In general, TLR1 is expressed at higher levels as compared to other TLRs. The highest expression of TLR1 is found in monocytes but it can also be expressed by macrophages, dendritic cells, B, T, and NK cells. In recent studies, several human TLR1 polymorphisms have been associated with impaired mycobacterial signaling and susceptibility to tuberculosis.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein
    基因ID
    9606
    UniProt
    Q15399
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
You are here:
客服