Macrophage Mannose Receptor 1 抗体 (Biotin)
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- 抗原 See all Macrophage Mannose Receptor 1 (MRC1) 抗体
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Macrophage Mannose Receptor 1 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- 特异性
- The monoclonal antibody 15-2 recognizes the mannose receptor (MR), also known as CD206, a member of the vertebrate C-type lectin family. The monoclonal antibody 15-2 prevents binding of glycoproteins including t-PA to MR. Detection of the MR with anti-MR monoclonal antibody 15-2 can substitute staining for mannose containing probes as labeled mannosylated BSA, a technique which is more cumbersome and less specific.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Protein G
- 免疫原
- Purified human mannose receptor from human placental tissue
- 克隆位点
- 15-02-14
- 亚型
- IgG1
- Top Product
- Discover our top product MRC1 Primary Antibody
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anti-Mannose Receptor, C Type 1 (MRC1) (AA 22-130) antibody
MRC1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5C11 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 FACS, WB, IP, ICC, IHC (fro) 宿主: 小鼠 Monoclonal 15-2 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 FACS, WB, IP, ICC, IHC (fro), Func 宿主: 小鼠 Monoclonal 15-2 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibody (PE)MRC1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15-2 PE
anti-Mannose Receptor, C Type 1 (MRC1) (AA 201-300) antibodyMRC1 适用: 人, 小鼠, 大鼠, 犬 FACS, WB, ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) (Internal Region) antibodyMRC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibody (FITC)MRC1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15-2 FITC
anti-Mannose Receptor, C Type 1 (MRC1) antibody (APC)MRC1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15-2 APC
anti-Mannose Receptor, C Type 1 (MRC1) (AA 225-492) antibodyMRC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CL0387 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.02 % sodium azid, 0.1 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
- 别名
- CD206 / MRC1 (MRC1 产品)
- 别名
- CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mrc1 antibody, MGC86525 antibody, MRC1 antibody, MRC1L-A antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, mannose receptor C-type 1 L homeolog antibody, mediator of replication checkpoint 1 antibody, MRC1 antibody, Mrc1 antibody, mrc1.L antibody, mrc1 antibody
- 背景
- The mannose receptor, is a pattern recognition receptor that is involved in both innate and adaptive immunity. The 175 kDa single-pass type I transmembrane receptor consists of 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. The structure is shared by the family of multi lectin mannose receptors: the phospholipase A2-receptor, DEC 205 and the novel C-type lectin receptor (mannose receptor X). The MR binds high-mannose structures on a wide range of gram positive and gram negative bacteria, yeasts, parasites and mycobacteria. The MR has also been shown to bind and internalize tissue-type plasminogen activator. MR's are present on monocytes and dendritic cells (DC) and are presumed to play a role in innate and adaptive immunity, the latter via processing by DC. The expression of MR as observed in immunohistology is present on tissue macrophages, dendritic cells, a subpopulation of endothelial cells, Kupffer cells and sperm cells. The expression of MR on monocytes increases during culture and can be enhanced by cytokines as IFN-gamma. Labeling of MR expressing monocytes/macrophages increases with prolonged incubation time probably due to internalization of the MR-antibody-complex.Synonyms: C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, CLEC13D, CLEC13DL, MRC1L1, Macrophage mannose receptor, Macrophage mannose receptor 1-like protein 1
- 基因ID
- 4360
- NCBI登录号
- NP_002429
- UniProt
- P22897
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