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C1S 抗体

C1S 适用: 人 WB, IHC (p), IP, IHC (fro), EIA, Func 宿主: 小鼠 Monoclonal M81 unconjugated
产品编号 ABIN1105612
发货至: 中国
  • 抗原 See all C1S 抗体
    C1S (Complement Component 1, S Subcomponent (C1S))
    适用
    • 55
    • 18
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    宿主
    • 43
    • 10
    • 2
    小鼠
    克隆类型
    • 46
    • 9
    单克隆
    标记
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    This C1S antibody is un-conjugated
    应用范围
    • 39
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    Monoclonal antibody M81 reacts with an epitope on human C protein activated C1s, a subcomponent of the first component of C (C1). The epitope recognised by the antibody M81 is domain IV and/or V of the gamma-domain of activated C1s. It blocks C4 activation and C4 binding to activated C1s. The antibody reacts around the binding site of C1s and reacts with both active and inactive C1s.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein G
    克隆位点
    M81
    亚型
    IgG1
    Top Product
    Discover our top product C1S Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.1 % bovine serum albumin
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    C1S (Complement Component 1, S Subcomponent (C1S))
    别名
    C1s (C1S 产品)
    别名
    AA959438 antibody, AI255193 antibody, AI327365 antibody, C1sa antibody, r-gsp antibody, C1S antibody, complement C1s antibody, complement component 1, s subcomponent 1 antibody, complement component 1, s subcomponent antibody, complement component 1, s subcomponent L homeolog antibody, complement C1s subcomponent antibody, C1S antibody, C1s1 antibody, C1s antibody, c1s antibody, c1s.L antibody, LOC100558615 antibody
    背景
    Activated C1s is a glycosylated single-polypeptide zymogen, MW 85 kD. Activation of the proenzyme C1s occurs through cleavage by the active form of C1r. The activated protease, activated C1s, consists of a disulfide-linked H chain and a L chain. Activated C1s is a serine protease and its catalytic site is located in the L chain. Activation of the classical C pathway is triggered by activated C1s which cleaves C4 and C2 to form the C3 convertase, C4bC2a.Synonyms: C1 esterase, Complement 1s, Complement C1s, Complement C1s subcomponent, Complement component 1 subcomponent s
    基因ID
    716
    NCBI登录号
    NP_001725
    UniProt
    P09871
    途径
    Complement System
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