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ATP7B 抗体 (AA 3-21)

ATP7B 适用: 人 WB, IHC, IP, IF/ICC 宿主: 小鼠 Monoclonal S62-29 unconjugated
产品编号 ABIN1098199
发货至: 中国
  • 抗原 See all ATP7B 抗体
    ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
    抗原表位
    • 15
    • 13
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-21
    适用
    • 37
    • 26
    • 21
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 39
    • 21
    小鼠
    克隆类型
    • 39
    • 21
    单克隆
    标记
    • 23
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATP7B antibody is un-conjugated
    应用范围
    • 41
    • 22
    • 18
    • 16
    • 13
    • 13
    • 13
    • 9
    • 9
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC)
    原理
    Anti-Copper-Transporting ATPase2 Mouse Monoclonal Antibody
    特异性
    This antibody recognizes human, mouse, and rat Copper-Transporting ATPase2.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein G affinity chromatography.
    免疫原
    Synthetic peptide correspond- ing to aa 3-21 (cytoplasmic N-terminus) of human Copper-Transporting ATPase2. (accession no. NP_000044.2).
    克隆位点
    S62-29
    亚型
    IgG1
    Top Product
    Discover our top product ATP7B Primary Antibody
  • 应用备注
    Immunoblotting: use at 1-2 μg/mL. A band of ~160 kDa is detected.
    Immunohistochemistry: use at 1-5 μg/mL.
    These are recommended concentrations.
    Enduser should determine optimal concentrations for their applications.
    Positive control: rat brain membranes.
    限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    Dilute in PBS or medium that is identical to that used in the assay system.
    浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    This product is stable for at least 1 year at -20°C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.
  • 抗原
    ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
    别名
    Copper-Transporting ATPase2 (ATP7B 产品)
    别名
    PWD antibody, WC1 antibody, WD antibody, WND antibody, Atp7a antibody, tx antibody, Hts antibody, PINA antibody, Wd antibody, ATP7B antibody, ATPase copper transporting beta antibody, ATPase, Cu++ transporting, beta polypeptide antibody, ATPase, Cu++ transporting, beta polypeptide (Wilson disease) antibody, copper-transporting ATPase 2 antibody, ATP7B antibody, Atp7b antibody, atp7b antibody, LOC592143 antibody
    背景
    P-type Cu(+) transporter,The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from cells. ATP7b (also known as Copper-Transporting ATPase2) transports copper in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene: A is found in the liver, kidney and brain, the shorter form B is found in brain, and the third isoform, known as WND/140KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.
    UniProt
    B7ZLR4
    途径
    Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
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