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Ankyrin G 抗体 (C-Term)

ANK3 适用: 人 WB, IF/ICC 宿主: 小鼠 Monoclonal S106-20 unconjugated
产品编号 ABIN1098195
发货至: 中国
  • 抗原 See all Ankyrin G (ANK3) 抗体
    Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))
    抗原表位
    • 12
    • 5
    • 1
    C-Term
    适用
    • 27
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 16
    • 13
    • 1
    小鼠
    克隆类型
    • 16
    • 14
    单克隆
    标记
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ankyrin G antibody is un-conjugated
    应用范围
    • 15
    • 14
    • 11
    • 7
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)
    原理
    Anti-Ankyrin-G Mouse Monoclonal Antibody
    特异性
    This antibody recognizes human, mouse, and rat Ankyrin-G.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein G affinity chromatography.
    免疫原
    Fusion protein corresponding to ~1,000 C-terminal amino acids of human Ankyrin G (accession no. NP_066267.2).
    克隆位点
    S106-20
    亚型
    IgG1
    Top Product
    Discover our top product ANK3 Primary Antibody
  • 应用备注
    Immunoblotting: use at 1-2 μg/mL. A band of >200 kDa is detected.
    These are recommended concentrations.
    Enduser should determine optimal concentrations for their applications.
    Positive control: rat brain membranes.
    限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    Dilute in PBS or medium that is identical to that used in the assay system.
    浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    This product is stable for at least 1 year at -20°C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.
  • 抗原
    Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))
    别名
    Ankyrin-G (ANK3 产品)
    别名
    ANK3 antibody, ankyrin-G antibody, 2900054D09Rik antibody, AI314020 antibody, Ank-3 antibody, AnkG antibody, Ankyrin-3 antibody, Ankyrin-G antibody, ANKYRIN-G antibody, ankyrin 3 antibody, ankyrin 3, node of Ranvier (ankyrin G) antibody, ankyrin 3, epithelial antibody, ANK3 antibody, legA6 antibody, PB000272.02.0 antibody, PY00018 antibody, ank3 antibody, Ank3 antibody
    背景
    Ankyrin-3,In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption (PubMed:23903368). {PubMed:17974005}., [Isoform 5]: May be part of a Golgi-specific membrane cytoskeleton in association with beta-spectrin. {PubMed:17974005}.,Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton. Ankyrins have binding sites for the beta subunit of spectrin and for at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers, and ion transporters in the plasma membrane.,Cytoplasm, cytoskeleton, Cell projection, axon, Cell membrane, sarcolemma, Cell junction, synapse, postsynaptic cell membrane, Lysosome, Cell membrane, sarcolemma, T-tubule,ANK-3, Ankyrin-G
    UniProt
    Q12955
    途径
    Synaptic Membrane, Maintenance of Protein Location, Skeletal Muscle Fiber Development
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