CCL4 抗体
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- 抗原 See all CCL4 抗体
- CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This CCL4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal CCL4 antibody was raised against a 15 amino acid peptide near the center of human CCL4.
- 亚型
- IgG
- Top Product
- Discover our top product CCL4 Primary Antibody
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- 应用备注
- CCL4 antibody can be used for detection of CCL4 by Western blot at 1 - 2 μg/mL.
- 说明
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(IN) Chemokine (C-C motif) ligand 4
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C
- 储存方法
- CCL4 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
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- 抗原
- CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
- 别名
- CCL4 (CCL4 产品)
- 背景
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CCL4, also known as macrophage inflammatory protein 1-beta (MIP1B), belongs to the intercrine beta (chemokine CC) family. Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells. While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ, with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes. Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells.
Synonyms: C-C motif ligand 4, macrophage inflammatory protein 1-beta, MIP1-beta, MIP1B, MIP1B1, ACT2, AT744.1, G-26, HC21, lymphocyte-activation gene 1, LAG-1, LAG1, SCYA2, SCYA4 - 分子量
- 10 kDa (calculated)
- 基因ID
- 6351
- NCBI登录号
- NP_002975
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