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- 抗原 See all CHCHD6 抗体
- CHCHD6 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHCHD6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- CHCHD6 is predicted to not cross-react to other members of the CHCHD family.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal CHCHD6 antibody was raised against a 17 amino acid peptide near the amino terminus of human CHCHD6.
- 亚型
- IgG
- Top Product
- Discover our top product CHCHD6 Primary Antibody
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anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (Internal Region) antibody
CHCHD6 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (AA 135-235) antibodyCHCHD6 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (AA 69-118) antibodyCHCHD6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (AA 95-144) antibodyCHCHD6 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (N-Term) antibodyCHCHD6 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (AA 1-235) antibodyCHCHD6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- CHCHD6 antibody can be used for detection of CHCHD6 by Western blot at 1 - 2 μg/mL.
- 说明
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(NT) Coiled-coil-helix-coiled-coil-helix domain-containing protein 6
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C
- 储存方法
- CHCHD6 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
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- 抗原
- CHCHD6 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6))
- 别名
- CHCHD6 (CHCHD6 产品)
- 别名
- CHCM1 antibody, PPP1R23 antibody, 0710001P09Rik antibody, 1700021B03Rik antibody, chchd6 antibody, hm:zeh0124 antibody, zgc:91802 antibody, coiled-coil-helix-coiled-coil-helix domain containing 6 antibody, coiled-coil-helix-coiled-coil-helix domain containing 6a antibody, CHCHD6 antibody, Chchd6 antibody, chchd6a antibody
- 背景
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CHCHD6 is a member of a family of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain and has been observed in a complex with the mitochondrial proteins mitofilin, SAM50, metaxins 1 and 2, and CHCHD3. CHCHD6 knockdown causes severe defects in mitochondrial cristae morphology as well as reductions in cell growth, ATP production and oxygen consumption. This decrease of CHCHD6 also led to a reduction in mitofilin protein levels, while a knockdown of mitofilin resulted in a reduced level of CHCHD6, suggesting coordinate regulation between these two proteins. CHCHD6 knockdown in human cancer cells enhances their sensitivity to genotoxic anticancer drugs, suggesting that CHCHD6 may be a potential therapeutic anti-tumor target.
Synonyms: Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, coiled coil helix cristae morphology 1, CHCM1, PPP1R23 - 分子量
- 26 kDa (calculated)
- 基因ID
- 84303
- NCBI登录号
- NP_115719
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