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CCL20 抗体 (Biotin)

CCL20 适用: 小鼠 WB 宿主: 大鼠 Monoclonal 4N5F7 Biotin
产品编号 ABIN1043839
发货至: 中国
  • 抗原 See all CCL20 抗体
    CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
    适用
    • 58
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    小鼠
    宿主
    • 44
    • 25
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    • 1
    大鼠
    克隆类型
    • 45
    • 28
    单克隆
    标记
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    This CCL20 antibody is conjugated to Biotin
    应用范围
    • 46
    • 23
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    Western Blotting (WB)
    特异性
    This product was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for mouse MIP-3alpha protein. A BLAST analysis was used to suggest cross-reactivity with MIP-3alpha from mouse sources based on 100% homology with the immunizing sequence. Cross-reactivity with MIP-3alpha from other sources has not been determined.
    产品特性
    MIP-3alpha (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3alpha inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3alpha also possesses antibacterial activity against E.coli and S.aureus. MIP-3alpha is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
    纯化方法
    purified
    免疫原
    Anti-MIP-3alpha (RAT) Monoclonal Antibody was produced in rat by repeated immunizations with mature full length recombinant mouse MIP-3alpha produced in E.coli followed by hybridoma development.
    Immunogen Type: Recombinant Protein
    克隆位点
    4N5F7
    亚型
    IgG
    Top Product
    Discover our top product CCL20 Primary Antibody
  • 应用备注
    Specific conditions for reactivity should be optimized by the end user.
    说明

    Gene Name: CCL20

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
    浓度
    1.0 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    有效期
    12 months
  • Lisignoli, Manferdini, Codeluppi, Piacentini, Grassi, Cattini, Filardo, Facchini: "CCL20/CCR6 chemokine/receptor expression in bone tissue from osteoarthritis and rheumatoid arthritis patients: different response of osteoblasts in the two groups." in: Journal of cellular physiology, Vol. 221, Issue 1, pp. 154-60, (2009) (PubMed).

  • 抗原
    CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
    别名
    MIP-3alpha (CCL20 产品)
    别名
    MIP-3ALPHA antibody, CCL20 antibody, si:dkey-150o13.1 antibody, CKb4 antibody, LARC antibody, MIP-3-alpha antibody, MIP-3a antibody, MIP3A antibody, SCYA20 antibody, ST38 antibody, MIP-3A antibody, MIP-3[a] antibody, Scya20 antibody, exodus-1 antibody, C-C motif chemokine ligand 20 antibody, chemokine (C-C motif) ligand 20b antibody, chemokine (C-C motif) ligand 20 antibody, CCL20 antibody, ccl20b antibody, Ccl20 antibody
    背景
    MIP-3α (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3α inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3α also possesses antibacterial activity against E.coli and S.aureus. MIP-3α is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
    Synonyms: MIP-3α , CCL20, C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1
    基因ID
    20297
    NCBI登录号
    NP_001153210
    UniProt
    O89093
    途径
    The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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