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IL-27 抗体

IL27 适用: 小鼠 WB 宿主: 大鼠 Monoclonal 3H12-F10 unconjugated
产品编号 ABIN1043836
发货至: 中国
  • 抗原 See all IL-27 (IL27) 抗体
    IL-27 (IL27) (Interleukin 27 (IL27))
    适用
    • 48
    • 44
    • 11
    • 1
    小鼠
    宿主
    • 57
    • 13
    • 5
    • 2
    大鼠
    克隆类型
    • 61
    • 16
    单克隆
    标记
    • 47
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-27 antibody is un-conjugated
    应用范围
    • 58
    • 38
    • 17
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for mouse and rat p28 protein. Cross-reactivity with IL-27 from other sources has not been determined.
    产品特性
    Mouse IL-27/p28 Subunit, also known as Interleukin-30, is a member of the IL-12 family of cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), the heterodimer formed is IL-27. Mouse p28 is a proinflammatory cytokine inducing immunomodulatory effects. Current research is underway to delineate specific biological functions.
    纯化方法
    purified
    过滤
    Sterile filtered
    免疫原
    This Protein A purified monoclonal antibody was produced in rats by repeated immunizations with mature length recombinant mouse p28 protein (produced in E.coli) followed by hybridoma development.
    Immunogen Type: Recombinant Protein
    克隆位点
    3H12-F10
    亚型
    IgG2a kappa
    Top Product
    Discover our top product IL27 Primary Antibody
  • 应用备注
    IL-27 is expressed in activated antigen presenting cells including monocytes, endothelial cells, and dendritic cells, for example mouse CD4 splenocytes. This purified antibody has been tested for use in western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 26 KDa in size corresponding to the mature mouse p28 protein, a non-glycosylated polypeptide chain consisting of amino acids, by western blotting in appropriate cell lysate or extract.
    说明

    Gene Name: IL27

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    有效期
    12 months
  • Murugaiyan, Mittal, Weiner: "Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 25, pp. 11495-500, (2010) (PubMed).

  • 抗原
    IL-27 (IL27) (Interleukin 27 (IL27))
    别名
    IL-27/p28 (IL27 产品)
    别名
    IL-27 antibody, IL-27A antibody, IL27A antibody, IL27p28 antibody, IL30 antibody, p28 antibody, RGD1561420 antibody, IL27 antibody, IL-27p28 antibody, Il30 antibody, interleukin 27 antibody, IL27 antibody, Il27 antibody
    背景
    Mouse IL-27/p28 Subunit, also known as Interleukin-30, is a member of the IL-12 family of cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), the heterodimer formed is IL-27. Mouse p28 is a proinflammatory cytokine inducing immunomodulatory effects. Current research is underway to delineate specific biological functions.
    Synonyms: Interleukin-27 subunit alpha, IL-27 subunit alpha, IL-27-A cytokine, IL27-A, p28, IL-30
    基因ID
    246779
    NCBI登录号
    NP_663611
    UniProt
    Q8K3I6
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