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IDO2 抗体

IDO2 适用: 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 1HC unconjugated
产品编号 ABIN1043821
发货至: 中国
  • 抗原 See all IDO2 抗体
    IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))
    适用
    • 51
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    小鼠
    宿主
    • 53
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    • 1
    小鼠
    克隆类型
    • 54
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    单克隆
    标记
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    This IDO2 antibody is un-conjugated
    应用范围
    • 55
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    Western Blotting (WB), ELISA
    特异性
    Anti-IDO2 was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above. IDO2 antibody is specific for mouse IDO2 protein. Cross-reactivity with IDO2 from other sources has not been determined.
    产品特性
    Indoleamine 2,3-dioxygenase 2 (IDO2) is related to IDO1, and may play a role in T and B Cell Immunity. IDO2’s role in immune regulation will be become clearer following the completion of genetic knock-out studies. IDO2 is expressed in a few select cell types and levels of protein expression appear to be very low, perhaps below the level of detection by IHC. Small-molecule inhibitors of indoleamine 2,3-dioxygenase (IDO) are currently being translated to clinic for evaluation as cancer therapeutics.
    过滤
    Sterile filtered
    免疫原
    Anti-IDO2 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with complete mouse IDO2 protein followed by hybridoma development.
    Immunogen Type: Recombinant Protein
    克隆位点
    1HC
    亚型
    IgG
    Top Product
    Discover our top product IDO2 Primary Antibody
  • 应用备注
    Anti-IDO2 antibody has been tested for use in ELISA, Western Blot, and IF. Specific conditions for reactivity should be optimized by the end user.
    说明

    Gene Name: Ido2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    有效期
    12 months
  • Wolff, Driever, Erdlenbruch, Kortmann, Rutkowski, Pietsch, Parker, Metz, Gnekow, Kramm: "Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol." in: Cancer, Vol. 116, Issue 3, pp. 705-12, (2010) (PubMed).

    Metz, Duhadaway, Rust, Munn, Muller, Mautino, Prendergast: "Zinc protoporphyrin IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase." in: Molecular cancer therapeutics, Vol. 9, Issue 6, pp. 1864-71, (2010) (PubMed).

  • 抗原
    IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))
    别名
    IDO2 (IDO2 产品)
    别名
    INDOL1 antibody, Indol1 antibody, AI265623 antibody, C230043N17Rik antibody, Ido-2 antibody, indoleamine 2,3-dioxygenase 2 antibody, IDO2 antibody, Ido2 antibody
    背景
    Indoleamine 2,3-dioxygenase 2 (IDO2) is related to IDO1, and may play a role in T and B Cell Immunity. IDO2’s role in immune regulation will be become clearer following the completion of genetic knock-out studies. IDO2 is expressed in a few select cell types and levels of protein expression appear to be very low, perhaps below the level of detection by IHC. Small-molecule inhibitors of indoleamine 2,3-dioxygenase (IDO) are currently being translated to clinic for evaluation as cancer therapeutics.
    Synonyms: Indoleamine 2,3-dioxygenase 2, Indol1, Indoleamine 2,3-dioxygenase-like protein 1, Indoleamine-pyrrole 2,3-dioxygenase-like protein 1, Ido-2, Ido 2, IDO2 antibody, anti-IDO2 antibody
    基因ID
    209176
    NCBI登录号
    NP_666061
    UniProt
    Q8R0V5
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