PRKAA1 (PRKAA1) ELISA试剂盒产品概述

Full name:
Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit ELISA试剂盒 (PRKAA1)
在www.antibodies-online.cn可供20 Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) ELISA试剂盒的11不同的供货商。 再加上,我们可以发PRKAA1 抗体 (318)PRKAA1 蛋白 (8)和数多这个蛋白质的别的产品。 总共355 PRKAA1产品已列进来了。
别名:
AI194361, AI450832, AL024255, AMPK, AMPK1, AMPKa1, AMPKalpha1, C130083N04Rik, cb116, im:7154392, PRKAA1, sb:cb130, wu:fa94c10
list all ELISA KIts 基因 基因ID UniProt
PRKAA1 108080  
PRKAA1 5562 Q13131
PRKAA1 65248 P54645

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适于 PRKAA1 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. The metformin-rescued P23H rhodopsin (显示 RHO ELISA试剂盒) was still intrinsically unstable and led to increased structural instability of the rod outer segments. These data suggest that improving the traffic of misfolding rhodopsin (显示 RHO ELISA试剂盒) mutants is unlikely to be a practical therapy, but also highlights the potential of altering translation through AMPK to improve protein function in other protein misfolding diseases

  2. Mechanistically, miR (显示 MLXIP ELISA试剂盒)-499 directly targets Fnip1 (显示 FNIP1 ELISA试剂盒), an AMP-activated protein kinase (AMPK (显示 PRKAA2 ELISA试剂盒))-interacting protein that negatively regulates AMPK, a known activator of PGC-1alpha (显示 PPARGC1A ELISA试剂盒). This miR (显示 MLXIP ELISA试剂盒)-499/Fnip1 (显示 FNIP1 ELISA试剂盒)/AMPK circuit can serve as a mechanism to couple muscle fiber type and mitochondrial function.

  3. dopamine is coupled to AMPK activation, which provides a substantial anti-inflammatory and bioenergetic advantage and reduces the severity of endotoxin-induced acute lung injury.

  4. AMPKalpha1 deficiency suppresses brown adipogenesis in favor of fibrogenesis during brown adipose tissue development.

  5. mitochondrial dysfunction triggers LKB1 (显示 STK11 ELISA试剂盒)-mediated AMPK activation, which stimulates Sirt2 (显示 SIRT2 ELISA试剂盒) phosphorylation, leading to activation of mTOR (显示 FRAP1 ELISA试剂盒)-RAPTOR (显示 RPTOR ELISA试剂盒) and Glut1 (显示 SLC2A1 ELISA试剂盒)-mediated glucose uptake.

  6. AMPK-dependent metabolic repair mechanisms are important for mitigating lung injury.

  7. these data demonstrated that LKB1 (显示 STK11 ELISA试剂盒)/AMPK signaling pathway activation improved the survival of diabetic mice complicated with endotoxemia. Thus, LKB1 (显示 STK11 ELISA试剂盒)/AMPK signaling pathway may serve as a potentially useful therapeutic target for severe infection in diabetic patients.

  8. We confirmed that procyanidins suppressed acute hyperglycemia with an oral glucose tolerance test in a dose-dependent manner.procyanidins, especially cinnamtannin A2, significantly ameliorate postprandial hyperglycemia at least in part by promoting GLUT4 (显示 SLC2A4 ELISA试剂盒) translocation to the plasma membrane by activating both insulin (显示 INS ELISA试剂盒)- and AMPK-signaling pathways.

  9. These findings demonstrate that the AMPK-TBC1D1 (显示 TBC1D1 ELISA试剂盒) signaling nexus interacts with the PKB (显示 AKT2 ELISA试剂盒)-mTOR (显示 FRAP1 ELISA试剂盒) pathway via IGF1 (显示 IGF1 ELISA试剂盒) secretion, which consequently controls expression of lipogenic genes in the adipose tissue

  10. AMPKa1 deficiency impairs autophagy-mediated monocyte differentiation and decreases monocyte/macrophage survival

Cow (Bovine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Endometrial inflammatory responses to lipopolysaccharide were also reduced by small molecules that activate or inhibit the intracellular sensor of energy, AMP-activated protein kinase (AMPK (显示 PRKAA2 ELISA试剂盒)).

  2. The results suggest that activation of AMPK represses global protein synthesis in mammary epithelial cells through inhibition of mTORC1 signaling.

  3. Nitrated oleic acid activates AMPK in endothelial cells.

  4. Findings suggest that ischemic factor stimulation of the blood brain barrier Na-K-Cl cotransporter (显示 SLC12A1 ELISA试剂盒) involves activation of AMPK.

  5. Results suggest that mitochondria-derived superoxide anions and peroxynitrite are required for Berberine-induced AMPK activation in endothelial cells.

  6. the expression, but not the kinase activity, of AMPK and CaMKKbeta is necessary for ADP signaling to eNOS (显示 NOS3 ELISA试剂盒)

Human Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. The metformin-rescued P23H rhodopsin (显示 RHO ELISA试剂盒) was still intrinsically unstable and led to increased structural instability of the rod outer segments. These data suggest that improving the traffic of misfolding rhodopsin (显示 RHO ELISA试剂盒) mutants is unlikely to be a practical therapy, but also highlights the potential of altering translation through AMPK to improve protein function in other protein misfolding diseases

  2. These results suggest that the LKB1 (显示 STK11 ELISA试剂盒)-AMPK-FoxO1 (显示 FOXO1 ELISA试剂盒) signaling pathway is a critical mediator of the antioxidant properties of H2, further supporting the idea that H2 acts as a signaling molecule to serve various physiological functions.

  3. this study shows taht AMPK reduces abnormal inflammatory responses and cellular senescence, which implicates as a potential therapeutic target for chronic obstructive pulmonary disease/emphysema

  4. Salusin-beta mediates high glucose-induced endothelial injury via disruption of AMPK signaling pathway.

  5. These findings identify a key mechanism of tolerance to Ras-Raf (显示 RAF1 ELISA试剂盒) pathway inhibitors and suggest that blocking either AMPK or autophagy in combination with these targeted inhibitors could increase tumor regression and decrease the likelihood of eventual recurrence.

  6. the Runx2 (显示 RUNX2 ELISA试剂盒) knockdown cells displayed activation of AMP-activated protein kinase (AMPKalpha (显示 GRK4 ELISA试剂盒)), the sensor of cellular metabolism. Importantly, the Runx2 (显示 RUNX2 ELISA试剂盒) knockdown in bone-derived cells resulted in increased sensitivity to both Erk1/2 (显示 MAPK1/3 ELISA试剂盒) inhibition and AMPKalpha (显示 GRK4 ELISA试剂盒) activation by PD184161 and metformin, respectively, despite increased IGF-1Rbeta and AMPKalpha (显示 GRK4 ELISA试剂盒) levels.

  7. Data indicate that siRNA-mediated knockdown of AMP-activated protein kinase (显示 PRKAA2 ELISA试剂盒) alpha (显示 PAK1 ELISA试剂盒) subunit (显示 POLG ELISA试剂盒) AMPKalpha1 inhibited icaritin-induced autophagy activation, but exacerbated colorectal cancer (CRC (显示 CALR ELISA试剂盒)) cell death.

  8. Retinoid-related orphan receptor alpha (RORalpha) reduction occurs in gastric cancer leading to the survival of tumor cells, which is attenuated by AMP-activated protein kinase (AMPK (显示 PRKAA2 ELISA试剂盒)), therefore, both RORalpha and AMPK are potential targets for the intervention and therapy in gastric carcinoma.

  9. BCLB (显示 BCL2L10 ELISA试剂盒) expression was a starvation stress sensor inducing apoptosis and autophagy simultaneously in HCC (显示 FAM126A ELISA试剂盒) cells through the adenosine monophosphate-activated protein kinase AMPK (显示 GRK4 ELISA试剂盒)-mTOR (显示 FRAP1 ELISA试剂盒) signaling cascade.

  10. findings show that dengue virus ( DENV) infection activates and requires the central metabolic regulator AMPK for its replication and the induction of lipophagy. This is required for the induction of lipophagy, but not basal autophagy, in DENV-infected cells

Zebrafish Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. AMPK-related pathways may be compromised during fluoxetine exposure as a result of increased miRNA abundance.

Xenopus laevis Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Constitutively active AMPKgammaR70Q significantly decreases Napi-IIa (显示 SLC34A1 ELISA试剂盒) oocyte cell membrane abundance, an effect not mimicked by catalytically-inactive AMPKalphaK45R.

  2. NDPK-A (显示 NME1 ELISA试剂盒) exists in a functional cellular complex with AMPK (显示 PRKAA2 ELISA试剂盒) and CFTR (显示 CFTR ELISA试剂盒) in airway epithelia, and NDPK-A (显示 NME1 ELISA试剂盒) catalytic function is required for the AMPK (显示 PRKAA2 ELISA试剂盒)-dependent regulation of CFTR (显示 CFTR ELISA试剂盒)

Pig (Porcine) Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) interaction partners

  1. Klotho (显示 KL ELISA试剂盒) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (显示 GRK4 ELISA试剂盒)-RUNX2 (显示 RUNX2 ELISA试剂盒) pathway.

  2. AMPK-mTOR (显示 FRAP1 ELISA试剂盒)-autophagy signaling is altered by intrauterine growth restriction in newborn piglets.

  3. Data indicate that 17beta-estradiol reduced Sertoli Cell proliferation by inhibiting microRNA miR (显示 MYLIP ELISA试剂盒)-1285 and thus activating AMP-activated protein kinase (AMPK (显示 PRKAA2 ELISA试剂盒)).

  4. L-Glutamine enhances enterocyte growth but did not affect abundances of total or phosphorylated AMPK protein.

  5. AMPK activity plays an important role in the maintenance of the spermatozoa quality during long-term storage of boar semen.

  6. AMPK, lying downstream of PKA, regulates at different levels mammalian spermatozoa membrane function.

  7. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK/ERK (显示 MAPK1 ELISA试剂盒)/TSC2 (显示 TSC2 ELISA试剂盒)/mTOR (显示 FRAP1 ELISA试剂盒) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

  8. AMPK deficiency or inhibition attenuated or mitigated ethanol exposure-triggered glucose intolerance and compromised cardiac contraction by increased phosphorylation of AMPK and acetyl-CoA carboxylase as well as autophagosome accumulation.

  9. AMPK functions to inhibit IGF-I (显示 IGF1 ELISA试剂盒)-stimulated PI3K pathway activation through stimulation of IRS-1 (显示 IRS1 ELISA试剂盒) serine 794 phosphorylation.

  10. acute activation of AMPK increases intestinal glucose absorption after administration of long-chain n-3 polyunsaturated fatty acids during gestation

PRKAA1 抗原简介

Antigen Summary

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternative names and synonyms associated with PRKAA1

  • protein kinase, AMP-activated, alpha 3 catalytic subunit (Prkaa3) Elisa Kit
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (PRKAA1) Elisa Kit
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (prkaa1) Elisa Kit
  • protein kinase, AMP-activated, alpha 1 catalytic subunit (Prkaa1) Elisa Kit
  • AI194361 Elisa Kit
  • AI450832 Elisa Kit
  • AL024255 Elisa Kit
  • AMPK Elisa Kit
  • AMPK1 Elisa Kit
  • AMPKa1 Elisa Kit
  • AMPKalpha1 Elisa Kit
  • C130083N04Rik Elisa Kit
  • cb116 Elisa Kit
  • im:7154392 Elisa Kit
  • PRKAA1 Elisa Kit
  • sb:cb130 Elisa Kit
  • wu:fa94c10 Elisa Kit

Protein level used designations for PRKAA1

protein kinase, AMP-activated, alpha 3 catalytic subunit , protein kinase, AMP-activated, alpha 1 catalytic subunit , 5'-AMP-activated protein kinase catalyti subunit alpha-1-like protein , 5'-AMP-activated protein kinase catalytic subunit alpha-1 , AMPK-activated protein kinase alpha-1 subunit , 5'-AMP-activated protein kinase alpha 1 catalytic subunit , 5'-AMP-activated protein kinase, catalytic alpha-1 chain , ACACA kinase , AMP -activate kinase alpha 1 subunit , AMP-activated protein kinase, catalytic, alpha-1 , AMPK alpha 1 , AMPK subunit alpha-1 , HMGCR kinase , acetyl-CoA carboxylase kinase , hydroxymethylglutaryl-CoA reductase kinase , tau-protein kinase PRKAA1 , AMPK alpha-1 chain , AMP-activated protein kinase, alpha 1 catalytic subunit , ampka1 , 5'-AMP-activated protein kinase alpha-1 catalytic subunit , AMPKalpha1 , 63 kDa subunit , AMPK 63 kDa subunit

GENE ID SPECIES
108080 Mus musculus
100009710 Equus caballus
100034740 Meleagris gallopavo
100145520 Xenopus (Silurana) tropicalis
100294665 Ovis aries
540404 Bos taurus
5562 Homo sapiens
65248 Rattus norvegicus
105787 Mus musculus
100001198 Danio rerio
495290 Xenopus laevis
427185 Gallus gallus
479351 Canis lupus familiaris
100145903 Sus scrofa
100174304 Pongo abelii
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