NEW: 请通过本地经销商订购 4A Biotech Co.,Ltd.

BAX Activator, BAM7

ABIN1888932 产品详细信息, 供应商: Log in to see
应用范围
Activation (Act)
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

原理 A potent and selective BAX activator
产品特性 A potent and selective BAX activator (EC₅₀ = 3.3 μM). BAM7 directly binds at the BH3-binding site, selective for BAX over other antiapoptotic and proapoptotic proteins. BAM7 triggers in vitro BAX oligomerization, BAX-mediated pore formation and BAX-dependent cell death. BAM7 selectively induces BAX-mediated apoptosis by triggering the hallmark features of intracellular BAX activation. BAM7 only kills the cell line that contains BAX, eliciting the biochemical and morphologic features of BAX-mediated apoptosis.
纯度 ≥ 98 % by HPLC
Chemical Name 3-Methyl-1-(4-phenyl-2-thiazolyl)-1​H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone]; BAM7
Formula C₂₁H₁₉N₅O₂S
Permeability Cell-permeable
分子量 405.47 g/mol
CAS-编号 331244-89-4
限制 仅限研究用
状态 Solid
注意事项 Protect from air and light
储存条件 -20 °C
有效期 24 months
厂商提供的图像
 image for BAX Activator, BAM7 (ABIN1888932) BAX Activator, BAM7