anti-TMEM173 (TMEM173) 抗体产品概述

Full name:
anti-Transmembrane Protein 173 抗体 (TMEM173)
在www.antibodies-online.cn可供143 Transmembrane Protein 173 (TMEM173) 抗体的23不同的供货商。 再加上,我们可以发TMEM173 蛋白 (11)TMEM173 试剂盒 (3)和数多这个蛋白质的别的产品。 总共164 TMEM173产品已列进来了。
别名:
2610307O08Rik, ERIS, Mita, MPYS, NET23, RGD1562552, STING
列出全部抗体 基因 基因ID UniProt
TMEM173 340061 Q86WV6
TMEM173 72512 Q3TBT3
TMEM173 498840  

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引用最多的anti-TMEM173 抗体

  1. Human Polyclonal TMEM173 Primary Antibody for ICC, IF - ABIN4356573 : Furr, Chauhan, Moerdyk-Schauwecker, Marriott: A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells. in Journal of neuroinflammation 2011 (PubMed)
    Show all 12 references for 4356573

  2. Human Polyclonal TMEM173 Primary Antibody for EIA, FACS - ABIN955253 : Sun, Li, Chen, Chen, You, Zhou, Zhou, Zhai, Chen, Jiang: ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 4 references for 955253

  3. Human Polyclonal TMEM173 Primary Antibody for WB - ABIN2783202 : Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... in Genome research 2004 (PubMed)
    Show all 4 references for 2783202

  4. Human Monoclonal TMEM173 Primary Antibody for FACS, ICC - ABIN4899624 : Schoggins, MacDuff, Imanaka, Gainey, Shrestha, Eitson, Mar, Richardson, Ratushny, Litvak, Dabelic, Manicassamy, Aitchison, Aderem, Elliott, García-Sastre, Racaniello, Snijder, Yokoyama, Diamond et al.: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. ... in Nature 2014 (PubMed)
    Show all 2 references for 4899624

  5. Human Polyclonal TMEM173 Primary Antibody for EIA, FACS - ABIN955254 : Zhong, Zhang, Lei, Li, Mao, Yang, Wang, Zhang, Shu: The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA. in Immunity 2009 (PubMed)
    Show all 2 references for 955254

更多抗TMEM173的相互作用对抗体

Human Transmembrane Protein 173 (TMEM173) interaction partners

  1. both IL-6 (显示 IL6 抗体) and RIG-I (显示 DDX58 抗体) are downstream molecules of STING along the DNA sensor pathway.

  2. We discuss three newly described monogenic autoinflammatory diseases [deficiency of adenosine deaminase 2 (显示 CECR1 抗体) (DADA2), a subtype of macrophage activation syndrome (MAS (显示 MAS1 抗体)), and stimulator of interferon (显示 IFNA 抗体) genes (STING)-associated vasculopathy with onset in infancy (SAVI)], discuss the possibilities of somatic mosaicism and digenic inheritance, and give an update on new concepts in pathways involved in familial Mediterranean fever (显示 MEFV 抗体)

  3. Structural analysis indicates that the 3 disease-associated mutations at positions 206, 281, and 284 of the STING protein define a novel cluster of amino acids with functional importance in the regulation of type I interferon (显示 IFNA 抗体) signaling

  4. a critical role of p38 (显示 CRK 抗体)-mediated USP21 (显示 USP21 抗体) phosphorylation in regulating STING-mediated antiviral functions and identifies p38 (显示 CRK 抗体)-USP21 (显示 USP21 抗体) axis as an important pathway that DNA virus adopts to avoid innate immunity responses.

  5. We conclude that the R71H-G230A-R293Q (HAQ) of TMEM173 is a null TMEM173 allele.

  6. Human herpesvirus 1 ICP27 interacted with TBK1 (显示 TBK1 抗体) and STING in a manner that was dependent on TBK1 (显示 TBK1 抗体) activity and the RGG motif in ICP27 and inhibited type I IFN induction through the cGAS-STING-TBK1 (显示 TBK1 抗体) pathway in human macrophages.

  7. Multivariate analysis supported TMEM173 as an independent prognostic factor.

  8. The mitochondrial damage-cGAS-STING-IRF3 (显示 IRF3 抗体) pathway is critically involved in metabolic stress-induced endothelial inflammation.

  9. These data uncover a promycobacterial role for STING-dependent OASL (显示 OASL 抗体) production during Mycobacterium leprae infection that directs the host immune response toward a niche that permits survival of the pathogen.

  10. cGAs recognizes bacterial/viral DNA, and is a strong activator of STING that can further activate IRF3 (显示 IRF3 抗体) and subsequent type I interferon (显示 IFNA 抗体) production. (Review)

Mouse (Murine) Transmembrane Protein 173 (TMEM173) interaction partners

  1. Yersinia YopJ negatively regulates IRF3 (显示 IRF3 抗体)-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling.

  2. demonstrate that in colon tumor model, therapeutic anti-CD47 (显示 CD47 抗体) preferentially relies on STING-mediated DNA sensing in dendritic cells

  3. STING is a central mediator of interferon (显示 IFNA 抗体) regulated inflammasome activation in Chlamydia trachomatis infection.

  4. this study shows that immune rejection of prostate cancer cells relies on Mus81 (显示 MUS81 抗体) and STING

  5. TRIF (显示 RNF138 抗体) and STING interacted directly, through their carboxy-terminal domains, to promote STING dimerization, intermembrane translocation, and signaling.

  6. We conclude that the R71H-G230A-R293Q (HAQ) of TMEM173 is a null TMEM173 allele.

  7. results show that resistance to HSV-1 in the trigeminal ganglia during acute infection is conferred in part by STING and IFN-alpha (显示 IFNA 抗体)/beta signaling in both bone marrow-derived and -resident cells, which coalesce to support a robust HSV-1-specific CD8 (显示 CD8A 抗体)(+) T cell response

  8. results suggest that LSm14A (显示 LSM14A 抗体) plays an important role in antiviral innate and adaptive immune responses by modulating MITA level in a cell type-specific manner

  9. STING and TRIF (显示 RNF138 抗体) Contribute to Mouse Sepsis, Depending on Severity of the Disease Model

  10. Data suggest that activation of either RIG-I (显示 DDX58 抗体)/MAVS (显示 MAVS 抗体) or STING pathways during acute intestinal tissue injury in mice resulted in IFN-I signaling that maintained gut (显示 GUSB 抗体) epithelial barrier integrity and reduced GVHD severity.

Pig (Porcine) Transmembrane Protein 173 (TMEM173) interaction partners

TMEM173 抗原简介

Antigen Summary

Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double- stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti- viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

Alternative names and synonyms associated with TMEM173

  • transmembrane protein 173 (TMEM173) 抗体
  • transmembrane protein 173 (Tmem173) 抗体
  • 2610307O08Rik 抗体
  • ERIS 抗体
  • Mita 抗体
  • MPYS 抗体
  • NET23 抗体
  • RGD1562552 抗体
  • STING 抗体

Protein level used designations for TMEM173

transmembrane protein 173 , N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner , endoplasmic reticulum IFN stimulator , endoplasmic reticulum interferon stimulator , hMITA , hSTING , mediator of IRF3 activation , mitochondrial mediator of IRF3 activation , stimulator of interferon genes protein , MMITA , mSTING , Stimulator of interferon genes protein , mitochondrial transmembrane protein 173

GENE ID SPECIES
606815 Canis lupus familiaris
462107 Pan troglodytes
694353 Macaca mulatta
100459760 Pongo abelii
340061 Homo sapiens
72512 Mus musculus
533661 Bos taurus
768990 Gallus gallus
100217389 Sus scrofa
498840 Rattus norvegicus
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