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Cathepsin B 蛋白

(Cathepsin B (CTSB))
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Cathepsin B Protein (CTSB) (AA 1-339) (GST tag) Cathepsin B Protein (CTSB) (AA 1-339) (GST tag) Cathepsin B Protein (CTSB) (AA 1-339) (GST tag) (ABIN1350702)

CTSB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Cathepsin B Protein (CTSB) (AA 21-339) (GST tag) Cathepsin B Protein (CTSB) (AA 21-339) (GST tag) Cathepsin B Protein (CTSB) (AA 21-339) (GST tag) (ABIN2752768)

CTSB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Cathepsin B Protein (CTSB) (AA 224-333) (GST tag) Cathepsin B Protein (CTSB) (AA 224-333) (GST tag) Cathepsin B Protein (CTSB) (AA 224-333) (GST tag) (ABIN1350704)

CTSB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Cathepsin B 蛋白 by Grade

Find Cathepsin B 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Cathepsin B 蛋白 by Origin

Find Cathepsin B 蛋白 for a variety of species such as anti-Human Cathepsin B, anti-Mouse Cathepsin B, anti-Rat Cathepsin B. The species listed below are among those available. Click on a link to go to the corresponding products.

Cathepsin B 蛋白 by Source

Here you will find Cathepsin B 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Cathepsin B 蛋白 by 蛋白类型

Here you can find Cathepsin B 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Cathepsin B 蛋白 by 应用范围

Find Cathepsin B 蛋白 validated for a specific application such as ELISA, SDS, WB, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Cathepsin B 蛋白 by 生物活性

Find Cathepsin B 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular Cathepsin B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350702
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2752768
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350704
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320464
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7194669
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7321072
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090924
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3090923
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3132803
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090922
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132804
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132802
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
  • (1)
Cat. No. ABIN2180942
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
  • (1)
Cat. No. ABIN1046771
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7519744
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Cathepsin B 蛋白

Hartmann, Lopez Cruz, Alameh, Ho, Rabideau, Pentelute, Bradley, Martchenko: "Characterization of Novel Piperidine-Based Inhibitor of Cathepsin B-Dependent Bacterial Toxins and Viruses." in: ACS infectious diseases, Vol. 4, Issue 8, pp. 1235-1245, (2018) (PubMed).

Peng, Zhang, Zheng, Liang, Li, Chen, Guo, Yoshina, Chen, Zhao, Wu, Liu, Mitani, Yu, Xue: "Cysteine protease cathepsin B mediates radiation-induced bystander effects." in: Nature, Vol. 547, Issue 7664, pp. 458-462, (2017) (PubMed).

Zilbermintz, Leonardi, Jeong, Sjodt, McComb, Ho, Retterer, Gharaibeh, Zamani, Soloveva, Bavari, Levitin, West, Bradley, Clubb, Cohen, Gupta, Martchenko: "Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting." in: Scientific reports, Vol. 5, pp. 13476, (2015) (PubMed).

Chowdhury, Moya, Bhilocha, McMillan, Vigliarolo, Zehbe, Phenix: "Prodrug-inspired probes selective to cathepsin B over other cysteine cathepsins." in: Journal of medicinal chemistry, Vol. 57, Issue 14, pp. 6092-104, (2014) (PubMed).

Zhao, Hua, Crowley, Ru, Ni, Shaw, Jiao, Ding, Qu, Hung, Huang, Liu, Ye, Ouyang, Cheng, Liu: "Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage." in: Cell research, Vol. 24, Issue 3, pp. 344-58, (2014) (PubMed).

Cao, Taggart, Berquin, Moin, Fong, Sloane: "Human gastric adenocarcinoma cathepsin B: isolation and sequencing of full-length cDNAs and polymorphisms of the gene." in: Gene, Vol. 139, Issue 2, pp. 163-9, (1994) (PubMed).

Chan, San Segundo, McCormick, Steiner: "Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 20, pp. 7721-5, (1986) (PubMed).

Aliases for Cathepsin B 蛋白

cathepsin B (CTSB) 蛋白
cathepsin B (Ctsb) 蛋白
cathepsin B S homeolog (ctsb.S) 蛋白
cathepsin B (LOC692390) 蛋白
APPS 蛋白
apps 蛋白
CB 蛋白
CPSB 蛋白
cpsb 蛋白
CTSB 蛋白
LOC692390 蛋白
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