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抗Human BDKRB1 抗体:
抗Rat (Rattus) BDKRB1 抗体:
抗Mouse (Murine) BDKRB1 抗体:
Human Polyclonal BDKRB1 Primary Antibody for IHC, IHC (p) - ABIN4285139
Gruber, Hoelscher, Ingram, Hanley: Genome-wide analysis of pain-, nerve- and neurotrophin -related gene expression in the degenerating human annulus. in Molecular pain 2012
Human Polyclonal BDKRB1 Primary Antibody for ELISA, WB - ABIN409118
Bengtson, Eddleston, Christiansen, Zuraw: Double-stranded RNA increases kinin B1 receptor expression and function in human airway epithelial cells. in International immunopharmacology 2007
kinin B1 receptor (B1R) gene ortholog(BDKRB1)was confirmed; putative Zn2+-binding motif HEXXH is not present (replaced by HDAWP); receptor binds [3H]Lys (显示 LYZ 抗体)-des (显示 DES 抗体)-Arg9-bradykinin (K(d) 0.36 nM) and exhibits a pharmacological profile like human B(1)R
Data show that mRNA and protein of bradykinin type 2 receptors, but not bradykinin type 1 receptors, were abundant in cultured c-Kit (显示 KIT 抗体)+ progenitor cells.
BKR1 and BKR2 (显示 BDKRB2 抗体) gene expression on peripheral monocytes is upregulated in essential hypertension
B1R agonist acts as a functional stimulus for the secretion of KLK1 (显示 KLK1 抗体) and KLK6 (显示 KLK1 抗体), an event relevant for kinin production and cell invasion, respectively
Bradykinin B1 receptor signaling depends on receptor endocytosis.
APJ (显示 APLNR 抗体) and B1R can form heterodimers in transfected HEK293 cells and activations of APJ (显示 APLNR 抗体) and B1R could up-regulate eNOS (显示 NOS3 抗体) phosphorylation
investigated if expression of B1 and B2 kinin receptors can be affected by IL-4 (显示 IL4 抗体) and IL-13 (显示 IL13 抗体); data show, for the first time, that IL-4 (显示 IL4 抗体) and IL-13 (显示 IL13 抗体) decrease kinin receptors in a STAT6 (显示 STAT6 抗体)-dependent mechanism
A novel B1R splice variant and promoter regulatory elements determine tissue-specific B1R expression.
the relevance of kinin B1 and B2 receptors in bladder cancer, was investigated.
CPM (显示 CPM 抗体) binding to extracellular loop 2 of the B1R results in positive allosteric modulation of B1R signaling, and disruption of this interaction could provide a novel therapeutic approach to reduce pathological B1R signaling.
This review focuses on airway MAPK/NFkappaB-dependent kinin receptor upregulation that links the environmental risk factors to airway hyperreactivity and airway inflammation.
B1 receptors are coupled to COX2 (显示 PTGS2 抗体) in causing endothelium-independent contractions in endotoxin-treated pig coronary arteries
study revealed that TRPA1 positively modulates the mechanical hyperalgesia induced by B1 receptor activation in the spinal cord and that the classical GPCR downstream molecules
Host kinin B1 receptor plays a protective role against melanoma progression.
Studied nitric oxide (NO) release, L-arginine (显示 GATM 抗体) (L-Arg) uptake and the expression of the cationic amino acid transporter (CAT) -1 (显示 SLC7A1 抗体) in endothelial cells obtained from B1 receptor knockout (B1-/-) and wild type (WT) mice.
Kinin B1R contributes to acute gouty attacks, including the ones facilitated by ACEi.
Kinin B1 receptor deletion affects bone healing in type 1 diabetic mice with femoral defects.
Kinin B1 receptor deficiency or antagonism diminishes apoptosis caused by cisplatin.
Bradykinin plays an important role in the pathogenesis of anti-collagen antibody-induced arthritis (CAIA). Bradykinin receptor beta 1, whose expression is induced in inflamed joint tissue, is important in the development of CAIA.
The kinin B1 receptor plays a significant role in the regulation of skeletal muscle proteolysis in the levator ani (显示 ANLN 抗体) muscle atrophy model.
Genetic deletion of kinin B1R attenuates cognitive deficits and blocks mRNA expression of IL-17 (显示 IL17A 抗体) and IFN-gamma (显示 IFNG 抗体) in mice subjected to autoimmune encephalitis.
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
B1 bradykinin receptor
, B1 like bradykinin receptor
, bradykinin receptor B2
, bradykinin receptor B1
, b1 bradykinin receptor-like
, BK-1 receptor
, bradykinin B1 receptor
, bradykinin receptor 1
, bradykinin receptor, beta 1
, kinin B1 receptor
, G-protein coupled receptor
, kinin B1