anti-serine Hydroxymethyltransferase 2 (Mitochondrial) (SHMT2) 抗体

SHMT2 encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. 再加上,我们可以发SHMT2 蛋白 (9)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SHMT2 6472 P34897
SHMT2 108037  
SHMT2 299857  
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antibodies-online.cn销售最多的anti-SHMT2 抗体

Showing 10 out of 36 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 IHC, WB 100 μL Log in to see 2至3个工作日
$229.00
详细
Bat 非结合性 IHC (p), WB 100 μg Log in to see 7至9个工作日
$493.17
详细
Bat 非结合性 IHC (p), WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: SHMT2 Antibody [NBP1-80755] - Staining of human tonsil shows strong cytoplasmic positivity in reaction center cells. Western Blot: SHMT2 Antibody [NBP1-80755] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells). 0.1 mL Log in to see 10至13个工作日
$491.63
详细
小鼠 非结合性 IHC, WB Immunohistochemistry: SHMT2 Antibody (3E9) [NBP2-45826] - Analysis of Carcinoma of Human thyroid tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120 for 3 min) Immunohistochemistry: SHMT2 Antibody (3E9) [NBP2-45826] - Analysis of Human lymph node tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) 0.1 mL Log in to see 8至11个工作日
$514.63
详细
非结合性 IHC, ELISA, WB 100 μg Log in to see 2至3个工作日
$446.88
详细
非结合性 IF, IHC, WB Western blot analysis of extracts of various cell lines, using SHMT2 antibody. 100 μL Log in to see 16 Days
$334.02
详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: SHMT2 Antibody [NBP2-20354] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:500 dilution. Immunohistochemistry-Paraffin: SHMT2 Antibody [NBP2-20354] - Immunohistochemical analysis of paraffin-embedded HeLa xenograft, using antibody at 1:500 dilution. 0.1 mL Log in to see 8至11个工作日
$514.63
详细
小鼠 非结合性 IHC, WB Western blot analysis of extracts of various cell lines, using SHMT2 antibody. 100 μL Log in to see 13至14个工作日
$302.50
详细

通过反应活性、应用领域、克隆类型和共轭标记 SHMT2 抗体

特性 应用范围 宿主 克隆类型
Human
,
,
Mouse (Murine)


Rat (Rattus)


引用最多的anti-SHMT2 抗体

  1. Human Polyclonal SHMT2 Primary Antibody for ICC, IF - ABIN4353390 : Kjellin, Johansson, Höög, Lehtiö, Jakobsson, Kjellman: Differentially expressed proteins in malignant and benign adrenocortical tumors. in PLoS ONE 2014 (PubMed)

  2. Human Polyclonal SHMT2 Primary Antibody for ICC, IF - ABIN4353389 : Kim, Fiske, Birsoy, Freinkman, Kami, Possemato, Chudnovsky, Pacold, Chen, Cantor, Shelton, Gui, Kwon, Ramkissoon, Ligon, Kang, Snuderl, Vander Heiden, Sabatini: SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. in Nature 2015 (PubMed)

更多抗SHMT2的相互作用对抗体

Human serine Hydroxymethyltransferase 2 (Mitochondrial) (SHMT2) interaction partners

  1. High SHMT2 expression is associated with idiopathic pulmonary fibrosis.

  2. Site-directed mutagenesis experiments on SHMT1 (显示 SHMT1 抗体) demonstrate that selective enzyme inhibition relies on the presence of a cysteine residue at the active site of SHMT1 (显示 SHMT1 抗体) (Cys204) that is absent in SHMT2.

  3. These results indicate that SHMT2 may be a valuable prognostic biomarker in ER-negative breast cancer cases

  4. our results for the first time showed that miR (显示 MLXIP 抗体)-615-5p prevents proliferation and migration through negatively regulating SHMT2 in HCC (显示 FAM126A 抗体).

  5. The SHMT-2 is the direct targets of miR (显示 MLXIP 抗体)-370 and miR (显示 MLXIP 抗体)-373, respectively, in human articular chondrocytes.

  6. High SHMT2 expression increases glycine-dependent nucleotide synthesis leading to bladder cancer growth.

  7. SHMT2 is required for glioblastoma multiforme cells to adapt to the tumour environment, but also renders these cells sensitive to glycine cleavage system inhibition

  8. SHMT1 (显示 SHMT1 抗体) exists in solution as a tetramer, both in the absence and presence of PLP (显示 PLP1 抗体), while SHMT2 undergoes a dimer-to-tetramer transition.

  9. The present study not only describes individual genetic variation that directly affects SHMT1 (显示 SHMT1 抗体) and SHMT2 activity, but provided insight into the overall regulation of the Folate and Methionine Cycles.

  10. SHMT1 (显示 SHMT1 抗体) and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis

Mouse (Murine) serine Hydroxymethyltransferase 2 (Mitochondrial) (SHMT2) interaction partners

  1. SHMT1 (显示 SHMT1 抗体) and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis

SHMT2 抗原简介

蛋白简介

This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SHMT2

  • serine hydroxymethyltransferase 2 (mitochondrial) (Chro.80302) 抗体
  • serine hydroxymethyltransferase 2 (mitochondrial) (shmt2) 抗体
  • serine hydroxymethyltransferase 2 (mitochondrial) L homeolog (shmt2.L) 抗体
  • serine hydroxymethyltransferase 2 (SHMT2) 抗体
  • serine hydroxymethyltransferase 2 (mitochondrial) (Shmt2) 抗体
  • serine hydroxymethyltransferase 2 (Shmt2) 抗体
  • 2700043D08Rik 抗体
  • AA408223 抗体
  • AA986903 抗体
  • GLYA 抗体
  • SHMT 抗体

Protein level used designations for SHMT2

serine hydroxymethyltransferase 2 (mitochondrial) , mitochondrial serine hydroxymethyltransferase , serine hydroxymethyltransferase, mitochondrial , GLY A+ , glycine auxotroph A, human complement for hamster , glycine hydroxymethyltransferase , serine aldolase , serine hydroxymethylase , serine methylase , threonine aldolase , SHMT

GENE ID SPECIES
3412258 Cryptosporidium hominis TU502
100144628 Danio rerio
447193 Xenopus laevis
6472 Homo sapiens
607458 Canis lupus familiaris
507197 Bos taurus
100009293 Oryctolagus cuniculus
108037 Mus musculus
299857 Rattus norvegicus
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