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PDE10A 抗体

(phosphodiesterase 10A (PDE10A))
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011].
PDE10A 抗体 PDE10A 抗体 PDE10A 抗体 (ABIN2728471)

PDE10A 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 1B2 unconjugated

PDE10A 抗体  (AA 508-779) PDE10A 抗体  (AA 508-779) PDE10A 抗体 (AA 508-779) (ABIN7436099)

PDE10A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

PDE10A 抗体  (N-Term) PDE10A 抗体  (N-Term) PDE10A 抗体 (N-Term) (ABIN6264085)

PDE10A 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

PDE10A 抗体 by 适用

Find PDE10A 抗体 for a variety of species such as anti-Human PDE10A, anti-Mouse PDE10A, anti-Rat PDE10A. The species listed below are among those available. Click on a link to go to the corresponding products.

PDE10A 抗体 by 应用范围

Find PDE10A 抗体 validated for a specific application such as WB, ELISA, IP, ICC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find PDE10A 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PDE10A 抗体 by 抗原表位

Find PDE10A 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PDE10A 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PDE10A 抗体. Click on a link to go to the corresponding products.

PDE10A 抗体 by 克隆

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PDE10A 抗体 by 标记

Find PDE10A 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PDE10A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (3)
Cat. No. ABIN2728471
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7436099
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, ICC, IF
Validations
  • (2)
Cat. No. ABIN6264085
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN1500071
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN7269297
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN564713
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN3186358
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN524248
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IF, FACS
Validations
  • (2)
Cat. No. ABIN2728472
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, ELISA, IHC, IP, ICC, IF, CM
Validations
  • (12)
Cat. No. ABIN2747045
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
Cat. No. ABIN6753822
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF, IHC (p)
Validations
Cat. No. ABIN7464812
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA
Validations
Cat. No. ABIN1451106
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Horse, Human, Rabbit, Rat
Application WB
Validations
Cat. No. ABIN5514456
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application
Validations
Cat. No. ABIN6899087
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PDE10A 抗体

Maréchal, Guillemette, Goupil, Blondin, Leclerc, Richard: "Cyclic nucleotide phosphodiesterases in human spermatozoa and seminal fluid: Presence of an active PDE10A in human spermatozoa." in: Biochimica et biophysica acta, Vol. 1861, Issue 2, pp. 147-156, (2017) (PubMed).

Goupil, Maréchal, El Hajj, Tremblay, Richard, Leclerc: "Identification and Localization of the Cyclic Nucleotide Phosphodiesterase 10A in Bovine Testis and Mature Spermatozoa." in: PLoS ONE, Vol. 11, Issue 8, pp. e0161035, (2016) (PubMed).

Li, Lee, Xi, Zhu, Gary, Ramírez-Alcántara, Gurpinar, Canzoneri, Fajardo, Sigler, Piazza, Chen, Andrews, Thomas, Lu, Li, Laan, Moyer, Russo, Eberhardt, Yet, Keeton, Grizzle, Piazza: "Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity." in: Oncogene, Vol. 34, Issue 12, pp. 1499-509, (2015) (PubMed).

Harada, Suzuki, Miura, Hasui, Kamiguchi, Ishii, Taniguchi, Kuroita, Takano, Stepanov, Halldin, Kimura: "Characterization of the binding properties of T-773 as a PET radioligand for phosphodiesterase 10A." in: Nuclear medicine and biology, Vol. 42, Issue 2, pp. 146-54, (2015) (PubMed).

Sancesario, Morrone, DAngelo, Castelli, Ferrazzoli, Sica, Martorana, Sorge, Cavaliere, Bernardi, Giorgi: "Levodopa-induced dyskinesias are associated with transient down-regulation of cAMP and cGMP in the caudate-putamen of hemiparkinsonian rats: reduced synthesis or increased catabolism?" in: Neurochemistry international, Vol. 79, pp. 44-56, (2015) (PubMed).

Mango, Bonito-Oliva, Ledonne, Nisticò, Castelli, Giorgi, Sancesario, Fisone, Berretta, Mercuri: "Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions." in: Neuropharmacology, Vol. 76 Pt A, pp. 127-36, (2014) (PubMed).

Heine, Sygnecka, Scherf, Berndt, Egerland, Hage, Franke: "Phosphodiesterase 2 inhibitors promote axonal outgrowth in organotypic slice co-cultures." in: Neuro-Signals, Vol. 21, Issue 3-4, pp. 197-212, (2013) (PubMed).

Tian, Vroom, Ghofrani, Weissmann, Bieniek, Grimminger, Seeger, Schermuly, Pullamsetti: "Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling." in: PLoS ONE, Vol. 6, Issue 4, pp. e18136, (2011) (PubMed).

Giorgi, Melchiorri, Nuccetelli, DAngelo, Martorana, Sorge, Castelli, Bernardi, Sancesario: "PDE10A and PDE10A-dependent cAMP catabolism are dysregulated oppositely in striatum and nucleus accumbens after lesion of midbrain dopamine neurons in rat: a key step in parkinsonism physiopathology." in: Neurobiology of disease, Vol. 43, Issue 1, pp. 293-303, (2011) (PubMed).

Ong, Gribble, Reimann, Lynch, Houslay, Baillie, Furman, Pyne: "The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon-like peptide-1 release." in: British journal of pharmacology, Vol. 157, Issue 4, pp. 633-44, (2009) (PubMed).

Aliases for PDE10A 抗体

phosphodiesterase 10A (PDE10A) 抗体
phosphodiesterase 10A (Pde10a) 抗体
HSPDE10A 抗体
Pde10a3 抗体
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