电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

WWP1 抗体

(WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1\; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
WWP1 抗体  (AA 152-260) WWP1 抗体  (AA 152-260) WWP1 抗体 (AA 152-260) (ABIN564794)

WWP1 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A7 unconjugated

WWP1 抗体 WWP1 抗体 WWP1 抗体 (ABIN7245725)

WWP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

WWP1 抗体  (AA 152-260) WWP1 抗体  (AA 152-260) WWP1 抗体 (AA 152-260) (ABIN524448)

WWP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B7 unconjugated

WWP1 抗体 by 适用

Find WWP1 抗体 for a variety of species such as anti-Human WWP1, anti-Mouse WWP1, anti-Rat WWP1. The species listed below are among those available. Click on a link to go to the corresponding products.

WWP1 抗体 by 应用范围

Find WWP1 抗体 validated for a specific application such as WB, ELISA, IF, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

WWP1 抗体 by 抗体来源

Find WWP1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

WWP1 抗体 by 抗原表位

Find WWP1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

WWP1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal WWP1 抗体. Click on a link to go to the corresponding products.

WWP1 抗体 by 克隆

Find WWP1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

WWP1 抗体 by 标记

Find WWP1 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular WWP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP, IF, IHC (p)
Validations
  • (6)
  • (6)
Cat. No. ABIN564794
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7245725
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN524448
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6266055
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN7271394
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN564793
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN524446
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN7261223
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
Cat. No. ABIN466175
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Human, Mouse, Rabbit
Application WB
Validations
  • (1)
Cat. No. ABIN6743154
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2774928
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
Cat. No. ABIN720910
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IP, IHC, IF
Validations
Cat. No. ABIN7120866
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p)
Validations
Cat. No. ABIN7467665
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IP
Validations
Cat. No. ABIN7452554
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our WWP1 抗体

Cho, Yoo, Yoon, Yoon: "β-dystroglycan is regulated by a balance between WWP1-mediated degradation and protection from WWP1 by dystrophin and utrophin." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1864, Issue 6 Pt A, pp. 2199-2213, (2018) (PubMed).

Basheer, Harris, Mentrup, Abreha, Thames, Lea, Swing, Copeland, Jenkins, Price, Matesic: "Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis." in: Journal of molecular and cellular cardiology, Vol. 88, pp. 1-13, (2015) (PubMed).

Cheng, Cao, Yuan, Li, Tong: "Knockdown of WWP1 inhibits growth and induces apoptosis in hepatoma carcinoma cells through the activation of caspase3 and p53." in: Biochemical and biophysical research communications, Vol. 448, Issue 3, pp. 248-54, (2014) (PubMed).

Chaudhary, Maddika: "WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ?Np73 levels." in: Molecular and cellular biology, Vol. 34, Issue 19, pp. 3754-64, (2014) (PubMed).

Subik, Shu, Wu, Liang, Hicks, Boyce, Schiffhauer, Chen, Chen, Tang, Xing: "The ubiquitin E3 ligase WWP1 decreases CXCL12-mediated MDA231 breast cancer cell migration and bone metastasis." in: Bone, Vol. 50, Issue 4, pp. 813-23, (2012) (PubMed).

Cao, Xue, Han, Ma, Chen, Tong: "WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts." in: The Journal of biological chemistry, Vol. 286, Issue 38, pp. 33447-56, (2011) (PubMed).

Peschiaroli, Scialpi, Bernassola, El Sherbini, Melino: "The E3 ubiquitin ligase WWP1 regulates ?Np63-dependent transcription through Lys63 linkages." in: Biochemical and biophysical research communications, Vol. 402, Issue 2, pp. 425-30, (2010) (PubMed).

Edwards, Clowes, Tsang, Connell, Sanderson, Luzio, Reid: "Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5." in: The Biochemical journal, Vol. 423, Issue 1, pp. 31-9, (2009) (PubMed).

Aliases for WWP1 抗体

WW domain containing E3 ubiquitin protein ligase 1 (WWP1) 抗体
WW domain containing E3 ubiquitin protein ligase 1 (Wwp1) 抗体
WW domain containing E3 ubiquitin protein ligase 1 (wwp1) 抗体
8030445B08Rik 抗体
AIP5 抗体
aip5 抗体
hSDRP1 抗体
hsdrp1 抗体
SDRP1 抗体
Tiul1 抗体
tiul1 抗体
WWP1 抗体
You are here:
客服