Uromodulin 抗体
(Uromodulin (UMOD))
This gene encodes uromodulin, the most abundant protein in normal urine. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney disease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy (FJHN). These disorders are characterized by juvenile onset of hyperuricemia, gout, and progressive renal failure. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq, Jul 2008].
recommended
UMOD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro), FACS, IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
Uromodulin 抗体 by Grade
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Uromodulin 抗体 by 适用
Find Uromodulin 抗体 for a variety of species such as anti-Human Uromodulin, anti-Mouse Uromodulin, anti-Rat Uromodulin. The species listed below are among those available. Click on a link to go to the corresponding products.
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Uromodulin 抗体 by 克隆形成能力
Find available monoclonal or polyclonal Uromodulin 抗体. Click on a link to go to the corresponding products.
Uromodulin 抗体 by 克隆
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Popular Uromodulin 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IHC (fro), FACS, IF (p), IF (cc)
Validations
- (2)
- (4)
Cat. No.
ABIN678473
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (2)
- (4)
Cat. No.
ABIN521253
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Dog
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7437641
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF
Validations
- (1)
- (3)
Cat. No.
ABIN521251
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN948613
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (2)
Cat. No.
ABIN7436381
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human
Application
IHC, IHC (p), IHC (fro), IF
Validations
- (2)
Cat. No.
ABIN364281
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN6265892
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7436384
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7436387
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6741678
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human
Application
IHC, ELISA, IHC (p), IHC (fro), IF
Validations
- (1)
Cat. No.
ABIN364496
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
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Cat. No.
ABIN5539604
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN5539603
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IHC (p)
Validations
- (1)
Cat. No.
ABIN2569925
Quantity
0.1 mg
Datasheet
Datasheet
Latest Publications for our Uromodulin 抗体
: "Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency." in: Nature communications, Vol. 11, Issue 1, pp. 970, (2020) (PubMed).: "Fate of Neutrophils during the Recovery Phase of Ischemia/Reperfusion Induced Acute Kidney Injury." in: Journal of Korean medical science, Vol. 32, Issue 10, pp. 1616-1625, (2018) (PubMed).
: "Blocking junctional adhesion molecule C promotes the recovery of cisplatin-induced acute kidney injury." in: The Korean journal of internal medicine, Vol. 32, Issue 6, pp. 1053-1061, (2018) (PubMed).
: "The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin." in: eLife, Vol. 4, pp. e08887, (2016) (PubMed).
: "Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes." in: PLoS ONE, Vol. 7, Issue 12, pp. e53175, (2013) (PubMed).
: "Mass spectrometric study of stone matrix proteins of human bladder stones." in: Urology, Vol. 82, Issue 2, pp. 295-300, (2013) (PubMed).
: "Proteomic study of renal uric acid stone." in: Urology, Vol. 80, Issue 2, pp. 260-6, (2012) (PubMed).
: "Differential regulation of NFAT5 by NKCC2 isoforms in medullary thick ascending limb (mTAL) cells." in: American journal of physiology. Renal physiology, Vol. 300, Issue 4, pp. F966-75, (2011) (PubMed).
: "Tamm-Horsfall protein-deficient thick ascending limbs promote injury to neighboring S3 segments in an MIP-2-dependent mechanism." in: American journal of physiology. Renal physiology, Vol. 300, Issue 4, pp. F999-1007, (2011) (PubMed).
: "Immunolocalization of ectonucleotidases along the rat nephron." in: American journal of physiology. Renal physiology, Vol. 290, Issue 2, pp. F550-60, (2006) (PubMed).
Aliases for Uromodulin 抗体
uromodulin (UMOD) 抗体uromodulin (Umod) 抗体
ADMCKD2 抗体
FJHN 抗体
HNFJ 抗体
HNFJ1 抗体
MCKD2 抗体
THGP 抗体
THP 抗体
urehr4 抗体
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