anti-Ubiquitin Specific Peptidase 1 (USP1) 抗体

USP1 encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. 再加上,我们可以发USP1 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
USP1 7398 O94782
USP1 230484 Q8BJQ2
USP1 313387 Q569C3

antibodies-online.cn销售最多的anti-USP1 抗体

Showing 10 out of 95 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-USP1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human brain WB Suggested Anti-USP1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Human brain 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
非结合性 EIA, IHC (p), WB 0.4 mL Log in to see 29至35个工作日
¥4,086.26
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非结合性 IP 100 μL Log in to see 25至31个工作日
¥3,977.17
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非结合性 IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: USP1 Antibody [ABIN2577927] - FFPE section of human thyroid carcinoma. Affinity purified rabbit anti-USP1 used at a dilution of 1:250. 100 μL Log in to see 25至31个工作日
¥3,977.17
详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and human liver tissue labeled with Anti-USP-1 Polyclonal Antibody, Unconjugated (ABIN675578) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and human glioma tissue labeled with Anti-USP-1 Polyclonal Antibody, Unconjugated (ABIN675578) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 5至7个工作日
¥2,610.23
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非结合性 WB USP1 Antibody (C-term)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the USP1 antibody detected the USP1 protein (arrow). 400 μL Log in to see 5至8个工作日
¥2,325.14
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非结合性 IHC (p), WB Western blot analysis of anti-USP1 Pab (ABIN388876) in HepG2 cell line lysate (35 µg/lane). USP1(arrow) was detected using the purified polyclonal antibody (1:60 dilution) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 5至8个工作日
¥2,325.14
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非结合性 IHC, WB 100 μg Log in to see 24至29个工作日
¥4,201.31
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非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
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Alexa Fluor 594 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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通过反应活性、应用领域、克隆类型和共轭标记 USP1 抗体

特性 应用范围 宿主 克隆类型 标记
Human , , , ,
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Mouse (Murine) , ,


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Rat (Rattus) , , ,


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引用最多的anti-USP1 抗体

  1. Human Polyclonal USP1 Primary Antibody for IP - ABIN257791 : Lee, Yang, Cohn, Sikdar, DAndrea, Myung: Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal USP1 Primary Antibody for IHC, IHC (p) - ABIN257792 : Murai, Yang, Dejsuphong, Hirota, Takeda, DAndrea: The USP1/UAF1 complex promotes double-strand break repair through homologous recombination. in Molecular and cellular biology 2011 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal USP1 Primary Antibody for IHC, IHC (p) - ABIN4364533 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

更多抗USP1的相互作用对抗体

Human Ubiquitin Specific Peptidase 1 (USP1) interaction partners

  1. USP1 is a key senescence regulator controlling genomic integrity.

  2. High USP1 expression is associated with glioma.

  3. USP1-UAF1 (显示 WDR48 抗体) complex promotes homologous recombination repair via multiple mechanisms: through FANCD2 (显示 FANCD2 抗体) deubiquitination, as well as by interacting with RAD51AP1 (显示 RAD51AP1 抗体).

  4. The results suggest that silencing USP1 inhibits cell proliferation and invasion in U2OS cells. Therefore, USP1 may provide a novel therapeutic target for the treatment of osteosarcoma.

  5. Translational regulation of the mRNA encoding USP1 is involved in the DNA damage response as a determinant of cisplatin resistance.

  6. Ubiquitination-specific proteases 1 (USP1)-mediated protein stabilization promotes glioblastoma (GBM) stem-like cells maintenance and treatment resistance, thereby providing a rationale for USP1 inhibition as a potential therapeutic approach against GBM.

  7. analysis of the function and regulation of the USP1-UAF1 (显示 WDR48 抗体) complex

  8. USP1, p21 and Spartan are translesion DNA synthesis regulators. (Review)

  9. No correlation was observed between the protein level of ubiquitin-specific protease 1 (USP1) and ubiquitinated PCNA (显示 PCNA 抗体) in BAF180 (显示 PBRM1 抗体) expressing cells

  10. USP1 phosphorylation at S313 is not critical for PCNA (显示 PCNA 抗体) deubiquitination, neither for binding to UAF1 (显示 WDR48 抗体) in a cellular environment.

Mouse (Murine) Ubiquitin Specific Peptidase 1 (USP1) interaction partners

  1. our results strongly suggest that Usp1 is involved in the regulation of centrosome duplication, at least in part via ID1 (显示 ID1 抗体), and Usp1 may exert its oncogenic activity, partially through inducing centrosome abnormality.

  2. Data suggest Usp1 down-regulation by autocleavage is critical for Usp1 to exert role in DNA interstrand crosslink repair; Usp1 role is de-ubiquitination of Fancd2 (Fanconi anemia complementation group D2 (显示 FANCD2 抗体)) and Pcna (proliferating cell nuclear antigen (显示 PCNA 抗体)).

  3. Homozygous Uaf1 (显示 WDR48 抗体)(-/-) embryos died at embryonic day 7.5 (E7.5). These mutant embryos were small and developmentally retarded.

  4. Autocleaved Usp1 remains a deubiquitylase because its fragments remain associated with Uaf1 (显示 WDR48 抗体), an enhancer of Usp1 activity, until the C-terminal fragment is selectively destroyed by the Arg/N-end rule pathway.

  5. Bone marrow from Fancd2 (显示 FANCD2 抗体)-/- mice and Usp1-/- mice exhibited marked hematopoietic defects.

  6. mouse Usp1 functions downstream in the Fanconi anemia (显示 PALB2 抗体) pathway, and its deubiquitination is required for Fancd2 (显示 FANCD2 抗体) nuclear foci assembly

USP1 抗原简介

蛋白简介

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.

Gene names and symbols associated with USP1

  • ubiquitin specific peptidase 1 (USP1) 抗体
  • ubiquitin specific peptidase 1 (usp1) 抗体
  • ubiquitin specific peptidase 1 (Usp1) 抗体
  • UBP 抗体
  • usp1-a 抗体

Protein level used designations for USP1

ubiquitin carboxyl-terminal hydrolase 1 , ubiquitin specific protease 1 , ubiquitin specific peptidase 1 , ubiquitin carboxyl-terminal hydrolase 1-like , deubiquitinating enzyme 1 , hUBP , ubiquitin carboxyl terminal hydrolase 1 , ubiquitin specific processing protease 1 , ubiquitin thioesterase 1 , ubiquitin thiolesterase 1 , ubiquitin-specific-processing protease 1 , ubiquitin specific peptdiase 1

GENE ID SPECIES
100070397 Equus caballus
447465 Xenopus laevis
456901 Pan troglodytes
695157 Macaca mulatta
100443075 Pongo abelii
7398 Homo sapiens
230484 Mus musculus
313387 Rattus norvegicus
424685 Gallus gallus
479549 Canis lupus familiaris
100523071 Sus scrofa
516328 Bos taurus
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