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Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. 再加上，我们可以发TBCE 抗体 (50) 和 TBCE 蛋白 (6)和数多这个蛋白质的别的产品。
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ARF1 (显示 ARF1 ELISA试剂盒)/TBCE-mediated cross-talk that coordinates COPI formation and tubulin (显示 TUBB ELISA试剂盒) polymerization at the Golgi.
We conclude from our study that the mutation of the TBCE gene affects the auditory nerve and the cochlear hair cells simultaneously, leading to progressive hearing loss
Tbce is critical for the maintenance of microtubules in mouse motor axons
Although loss of function of TBCE has been documented to impact multiple developmental processes, the present findings provide evidence that hypomorphic TBCE mutations primarily drive neurodegeneration
Sanjad-Sakati syndrome molecular pathology has been shown to be due to mutations in the TBCE gene on chromosome 1q42-q43.
the role of the human TBCE and TBCB chaperones in alpha-tubulin (显示 TUBA4A ELISA试剂盒)-beta-tubulin (显示 TUBB ELISA试剂盒) dissociation, was investigated.
tudies confirmed elevated expression of three target antigens RAB38, TBCE, and DUSP12 in CML.
TBCE has a role in membrane trafficking in the Golgi and late endosomal compartments, tubulin (显示 TUBB ELISA试剂盒) assembly, and the development of the parathyroid
The tubulin-specific chaperone E (Tbce) mutation described here suggests that alterations in tubulin assembly lead to retrograde degeneration of motor axons, ultimately resulting in motoneuron cell death.
Reviews recent findings on the molecular mechanisms of the development of the parathyroid glands, with special emphasis on the possible role of tubulin chaperone E (TBCE), implicated in the hypopathyroidism, retardation and dysmorphism (HRD) syndrome.
TBCE, TBCB and alpha-tubulin (显示 TUBA4A ELISA试剂盒) form a ternary complex after heterodimer dissociation. These complexes might serve to escort alpha-tubulin (显示 TUBA4A ELISA试剂盒) towards degradation or recycling, depending on the cell requirements.
Depletion of Op18 (显示 STMN1 ELISA试剂盒) by means of RNA interference increased the susceptibility of tubulin (显示 TUBB ELISA试剂盒) to TBCE or E-like (显示 TBCEL ELISA试剂盒) mediated disruption, while overexpressed Op18 (显示 STMN1 ELISA试剂盒) exerted a tubulin (显示 TUBB ELISA试剂盒)-protective effect.
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex\; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.
progressive motor neuropathy
, tubulin-folding cofactor E
, Kenny-Caffey syndrome
, tubulin-specific chaperone E
, beta-tubulin cofactor E