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TRIM63 encodes a member of the RING zinc finger protein family found in striated muscle and iris. 再加上，我们可以发TRIM63 抗体 (152) 和 TRIM63 蛋白 (6)和数多这个蛋白质的别的产品。
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Dexamethasone-induced MuRF1 upregulation was significantly attenuated in C2C12 myotubes by resveratrol in vitro, but this effect on C2C12 myotubes was abrogated by a knockdown of NF-kappaB (显示 NFKB1 ELISA试剂盒), suggesting that the beneficial effect of resveratrol was NF-kappaB (显示 NFKB1 ELISA试剂盒) dependent. Our findings provide novel information about the ability of resveratrol to prevent or treat muscle atrophy induced by CKD.
Iron-induced skeletal muscle atrophy is suggested to involve the E3 ubiquitin ligase mediated by the reduction of Akt (显示 AKT1 ELISA试剂盒)-FOXO3a (显示 FOXO3 ELISA试剂盒) signaling by oxidative stress.
MAFbx (显示 FBXO32 ELISA试剂盒) mRNA expression was decreased in old mice relative to adult mice, whereas MuRF1 mRNA expression was less affected by ageing
MuRF2 (显示 TRIM55 ELISA试剂盒) regulates PPARgamma1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet.
MuRF1 directly interacts with PPARalpha (显示 PPARA ELISA试剂盒), mono-ubiquitinates it, and targets it for nuclear export to inhibit fatty acid oxidation in a proteasome independent manner.
Increased Expression of MuRF1 Is Associated with Radiation-induced Laryngeal Muscle Atrophy.
MURF1 was upregulated in cancer cachexia mice.
Expression of USP19 (显示 USP19 ELISA试剂盒) correlates with that of MuRF1 and MAFbx/atrogin-1 (显示 FBXO32 ELISA试剂盒) in skeletal muscles
Sunitinib is able to restrain the overactivation of STAT3 (显示 STAT3 ELISA试剂盒) and MuRF-1 pathways, involved in enhanced muscle protein catabolism during cancer cachexia.
provide evidence that high CO2 activates skeletal muscle atrophy via AMPKalpha2 (显示 PRKAA2 ELISA试剂盒)-FoxO3a (显示 FOXO3 ELISA试剂盒)-MuRF1, which is of biological and potentially clinical significance in patients with lung diseases and hypercapnia
this study shows that aspartate suppresses lipopolysaccharide-induced MuRF1 expression in skeletal muscle via activation of Akt (显示 AKT1 ELISA试剂盒) signaling, and inhibition of AMPKa and FOXO1 (显示 FOXO1 ELISA试剂盒) signaling
the involvement of oxidative stress in the atrophy of COPD peripheral muscle cells in vitro, via the FoxO1/MuRF1/atrogin-1 signaling pathway of the ubiquitin/proteasome system
The mitochondrial damage-cGAS-STING-IRF3 (显示 IRF3 ELISA试剂盒) pathway is critically involved in metabolic stress-induced endothelial inflammation.
Altogether, these results suggest a novel function for p63 (显示 RPE65 ELISA试剂盒) as a contributor to muscular atrophic processes via the regulation of multiple genes, including the muscle atrophy gene Trim63.
A novel protein aggregate myopathies and cardiomyopathy resulting from combined homozygous MuRF1 null mutation and heterozygous MuRF3 (显示 TRIM54 ELISA试剂盒) missense mutation.
Vitamin D3 might have an inhibitory effect on the expression of MAFbx (显示 FBXO32 ELISA试剂盒) and MuRF1 in skeletal muscle.
MURF1 expression intended to be increased in the skeletal muscle of patients with malignant disease even before cancer related cachexia weight loss.
TRIM63 gene expression involved in skin hyperpigmentation.
Skeletal muscle atrophy induced by Angiotensin II involves activation of MuRF1 expression.
These data strongly supported that rare variants in MuRF1 and MuRF2 (显示 TRIM55 ELISA试剂盒) are associated with higher penetrance and more severe clinical manifestations of hypertrophic cardiomyopathy.
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.
ring finger protein 29
, tripartite motif-containing protein 55
, muscle-specific RING finger protein 2
, tripartite motif-containing 63
, ring finger protein 30
, muscle specific ring finger protein 1
, E3 ubiquitin-protein ligase TRIM63
, muscle ring finger protein 1
, muscle specific RING finger protein-1
, e3 ubiquitin-protein ligase TRIM63-like
, tripartite motif containing 63
, iris ring finger protein
, muscle specific ring finger protein 2
, muscle-specific RING finger protein 1
, ring finger protein 28
, striated muscle RING zinc finger protein
, tripartite motif-containing protein 63
, tripartite motif protein 63