Transmembrane Protein 27 蛋白 (TMEM27)

TMEM27 encodes a transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. 再加上,我们可以发TMEM27 抗体 (26)TMEM27 试剂盒 (18)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
TMEM27 57393 Q9HBJ8
TMEM27 57394 Q9ESG4
TMEM27 57395 Q9ESG3

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Showing 10 out of 15 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 68至77个工作日
¥106,677.42
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大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 48至57个工作日
¥108,861.33
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大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 48至57个工作日
¥108,861.33
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Insect Cells rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 68至77个工作日
¥151,831.10
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人细胞 Fc Tag 100 μg Log in to see 14至15个工作日
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小麦胚 GST tag 10 μg Log in to see 29至34个工作日
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HOST_HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 28至34个工作日
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大肠杆菌(E. Coli) His tag 100 μg Log in to see 9至12个工作日
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酵母菌 Cow His tag   1 mg Log in to see 24至35个工作日
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酵母菌 大鼠 His tag   1 mg Log in to see 24至35个工作日
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TMEM27 蛋白 by Origin and Source

Origin 在表达 标记
Human , , , ,
, , , ,
Mouse (Murine) ,
, , ,
Rat (Rattus) ,
,

更多Transmembrane Protein 27 (TMEM27)互动伙伴

Human Transmembrane Protein 27 (TMEM27) interaction partners

  1. Lack of expression of the TMEM27 in conventional renal cell carcinoma (显示 MOK 蛋白) defines a group of patients at high risk for cancer-related death.

  2. Tmem27 is present in human serum and its levels are significantly lower in subjects with autoimmune diabetes as compared to healthy individuals.

  3. Bace2 (显示 BACE2 蛋白) specifically targets Tmem27 and cleaves its extracellular domain, which is then shed from the plasma membrane of pancreatic beta cells.

  4. Tmem27 dimerization is a dynamic process involving Bace2 (显示 BACE2 蛋白)

  5. Collectrin and ACE2 (显示 ACE2 蛋白) in renal and intestinal amino acid transport.

  6. Data support a role for TMEM27 in glucose-induced insulin (显示 INS 蛋白) secretion but not in cell proliferation. The finding that its cleavage is not specific to beta cells challenges the current support for its use as a potential beta cell mass biomarker.

  7. Collectrin has a role in amino acid transpor in the kidney [review]

  8. the first human study of the gene TMEM27 and an attempt to shine a light on genotype-phenotype correlation in Turner syndrome patients.

  9. No TMEM27 gene mutations were discovered among 26 patients showing a phenotype resembling Dent's disease

Mouse (Murine) Transmembrane Protein 27 (TMEM27) interaction partners

  1. this study shows that Tmem27-mediated cross-presentation supports intrahepatic adaptive antiviral immune responses and may lead to insights into the nature of how the liver acts as a primary site of CD8 (显示 CD8A 蛋白)+ T cell activation

  2. analysis of the interaction of amino acid transporters B0AT1 (显示 SLC6A19 蛋白) and B0AT3 with their ancillary protein collectrin

  3. Collectrin is a consequential link between the transport of l-arginine (显示 GATM 蛋白) and endothelial nitric oxide synthase (显示 NOS3 蛋白) uncoupling in hypertension.

  4. Collectrin and ACE2 (显示 ACE2 蛋白) in renal and intestinal amino acid transport.

  5. transcriptional hierarchy between HNF-1beta (显示 HNF1B 蛋白) and PKD (显示 PRKD1 蛋白) (polycystic kidney disease) genes expressed in the primary cilia of collecting duct cells has been suggested, and collectrin is one of such HNF-1beta (显示 HNF1B 蛋白) regulated genes

  6. Tmem27 is a pancreatic beta cell transmembrane protein that regulates cell growth of pancreatic islets

  7. Our data suggest that collectrin is a novel mediator of renal amino acid transport and may provide further insight into the pathogenesis of a number of human disease correlates.

  8. data identify collectrin as a key regulator of renal amino acid uptake

  9. Collectrin has a role in amino acid transpor in the kidney [review]

  10. functional association of mutant B(0)AT1 (显示 SLC6A19 蛋白) transporters with ACE2 (显示 ACE2 蛋白) and collectrin in intestine and kidney, respectively, participates in the phenotypic heterogeneity of Hartnup disorder

蛋白简介TMEM27

蛋白简介

This gene encodes a transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells.

Gene names and symbols associated with TMEM27

  • transmembrane protein 27 (tmem27)
  • si:dkey-194e6.1 (si:dkey-194e6.1)
  • transmembrane protein 27 (TMEM27)
  • transmembrane protein 27 (Tmem27)
  • 0610008J07Rik 蛋白
  • collectrin 蛋白
  • MGC68634 蛋白
  • NX-17 蛋白
  • Nx17 蛋白
  • tmem27 蛋白

Protein level used designations for TMEM27

transmembrane protein 27 , kidney-specific membrane protein , collectrin

GENE ID SPECIES
379678 Xenopus laevis
402976 Danio rerio
418622 Gallus gallus
100144643 Xenopus (Silurana) tropicalis
57393 Homo sapiens
57394 Mus musculus
57395 Rattus norvegicus
513188 Bos taurus
611445 Canis lupus familiaris
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