Transmembrane Protease, Serine 11A 蛋白 (TMPRSS11A)

Probable serine protease which may play a role in cellular senescence. 再加上,我们可以发TMPRSS11A 抗体 (14)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
TMPRSS11A 339967 Q6ZMR5
TMPRSS11A 194597 Q3UQ41
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Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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TMPRSS11A 蛋白 by Origin and Source

Origin 在表达 标记
Human
,
Mouse (Murine)
,

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Human Transmembrane Protease, Serine 11A (TMPRSS11A) interaction partners

  1. ECRG1 Arg290Gln polymorphism significantly affects the susceptibility but not the prognosis of esophageal squamous cell carcinoma patients in low-risk north Indian population.

  2. This suggests that substitution of the arginine in the conserved catalytic domain of the ECRG1 protein might reduce its catalytic capacity by impacting its 3-dimensional conformation, thereby causing the genetic susceptibility to ESCC. [review]

  3. Data show that the allele types of ECRG1 were Arg/Arg (54.2%), Arg/Gln (45.8%) and Gln/Gln (0.00%), and the allele types of FGFR4 amino acid 388 were Arg/Arg (8.3%), Arg/Gly (54.2%) and Gly/Gly (37.5%).

  4. A statistically significantly increased risk of ESCC was found to be associated with the ECRG1 Arg/Gln and Gln/Gln genotype.

  5. Data show that ECRG4 (显示 C2orf40 蛋白) interacts directly with ECRG1 to upregulate p21 protein (显示 NRAS 蛋白) expression, induce cell cycle G1 phase block and inhibit cancer cells proliferation in ESCC.

  6. findings indicate that ECRG1 may be a candidate tumor suppressor gene for esophageal cancer involved in cell-cycle control

  7. DNA polymorphisms in the coding region of ECRG1 are associated with poor outcome after surgical resection in esophageal carcinoma.

  8. no significant association between single nucleotide polymorphisms Arg/Arg, Arg/Gln and Gln/Gln and survival in oral squamous cell carcinoma

Mouse (Murine) Transmembrane Protease, Serine 11A (TMPRSS11A) interaction partners

  1. A comprehensive phenotypic analysis of mice deficient in two of the most widely expressed HAT/DESC proteases, TMPRSS11A and HAT, was performed.

蛋白简介TMPRSS11A

蛋白简介

Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest.

Gene names and symbols associated with TMPRSS11A

  • transmembrane protease, serine 11A (TMPRSS11A)
  • transmembrane protease serine 11A (LOC517049)
  • transmembrane protease serine 11A (LOC100482139)
  • transmembrane protease serine 11A (LOC100525933)
  • transmembrane protease, serine 11a (Tmprss11a)
  • ECRG1 蛋白
  • Gm7 蛋白

Protein level used designations for TMPRSS11A

transmembrane protease, serine 11A , airway trypsin-like protease 1 , epidermal type II transmembrane serine protease , epidermal type-II transmembrane serine protease , esophageal cancer-susceptibility gene 1 protein , transmembrane protease serine 11A , DESC-3 , serine protease DESC3

GENE ID SPECIES
471224 Pan troglodytes
482173 Canis lupus familiaris
517049 Bos taurus
711430 Macaca mulatta
100067321 Equus caballus
100384938 Callithrix jacchus
100432848 Pongo abelii
100482139 Ailuropoda melanoleuca
100525933 Sus scrofa
100590301 Nomascus leucogenys
339967 Homo sapiens
194597 Mus musculus
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