Transient Receptor Potential Cation Channel, Subfamily M, Member 1 (TRPM1) ELISA试剂盒

TRPM1 encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. 再加上,我们可以发TRPM1 抗体 (18)TRPM1 蛋白 (7)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
TRPM1 4308 Q7Z4N2
小鼠 TRPM1 TRPM1 17364 Q2TV84
大鼠 TRPM1 TRPM1 361586 Q2WEA5

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Horse (Equine) Transient Receptor Potential Cation Channel, Subfamily M, Member 1 (TRPM1) interaction partners

  1. The C > T SNP in intron 11 of the TRPM1 transcript found in Congenital stationary night-blindness horses introduces a functional binding site for the tissue-specific neuro-oncological ventral antigen 1 (Nova-1 (显示 NOVA1 ELISA试剂盒))

  2. Evidence for a retroviral insertion in TRPM1 as the cause of congenital stationary night blindness and leopard complex spotting in the horse.

  3. In the Miniature Horse, congenital stationary night blindness is perfectly associated with leopard complex spotting patterns and SNPs in the candidate gene TRPM1.

  4. Re-sequencing of the gene and associated splice sites within the 105 624 bp genomic region of TRPM1 led to the discovery of 18 SNPs.

  5. Decreased expression of TRPM1 in the eye and the skin may alter bipolar cell signaling as well as melanocyte function, thus causing both stationary night blindness and coat spotting patterns in horses.

Human Transient Receptor Potential Cation Channel, Subfamily M, Member 1 (TRPM1) interaction partners

  1. Loss of TRPM1 mRNA expression appears to be a crucial event in the progression of melanoma to a more malignant, metastatic phenotype.

  2. This study reveals the structural underpinnings of TRPML1 (显示 MCOLN1 ELISA试剂盒)'s regulation, assembly and pathogenesis.

  3. Affected family members harboured the homozygous 1-bp deletion c.2394delC in exon 18 of the TRPM1 gene, whereas their unaffected parents were heterozygous carriers.

  4. genotype-phenotype correlations showed that this eye phenotype was secondary to homozygous deletion of TRPM1, the gene responsible for autosomal recessive congenital stationary night blindness. The main differential diagnosis is ceroid lipofuscinosis.

  5. these data indicate that purified TRPM1 is mostly dimeric. The three-dimensional structure of TRPM1 dimers is characterized by a small putative transmembrane domain and a larger domain with a hollow cavity.

  6. visual deficits in melanoma associated (显示 ZNF654 ELISA试剂盒) retinopathy are caused by the uptake of TRPM1 autoantibodies into ON-bipolar cells

  7. This is the first reported case of a melanoma-associated (显示 ZNF654 ELISA试剂盒) retinopathy diagnosed utilizing the innovative approach of testing for serum TRPM1 autoantibodies.

  8. These data suggest differences in coupling of TRPM1 function to mGluR6 (显示 GRM6 ELISA试剂盒) signaling explain different cellular responses to glutamate (显示 GRIN1 ELISA试剂盒) in the retina and the skin.

  9. We found 13 different mutations in the TRPM1 gene in congenital stationary night blindness.

  10. The results expand the mutation spectrum of NYX (显示 NYX ELISA试剂盒), CACNA1F (显示 CACNA1F ELISA试剂盒) and GRM6 (显示 GRM6 ELISA试剂盒). They also suggest that NYX (显示 NYX ELISA试剂盒) mutations are a common cause of congenital stationary night blindness (CSNB (显示 CSN2 ELISA试剂盒)),No variations were found in TRPM1.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily M, Member 1 (TRPM1) interaction partners

  1. This study confirmed the localization of LRIT3 at the dendritic tips of depolarizing bipolar cells in mouse retina and demonstrated the dependence of TRPM1 localization on the presence of LRIT3.

  2. results indicate that the serum of a patient with PR contained an antibody against TRPM1 caused an acute death of retinal ON bipolar cells of mice

  3. TRPM1 is not essential for the development of hearing or balance in the mouse model and it is unlikely that TRPM1 is the hair cell mechanotransduction channel.

  4. The data indicates that the A1068T mutant TRPM1 acts as a dominant negative with respect to TRPM1 channel function.

  5. Results suggest a model in which the Gbetagamma dimer that is released as a result of the dissociation from Galpha(o (显示 GNAO1 ELISA试剂盒)) upon activation of mGluR6 (显示 GRM6 ELISA试剂盒) closes the TRPM1 channel, perhaps via a direct interaction.

  6. The results suggested that the TRPM1 channel in metabotropic glutamate receptor 6 (显示 GRM6 ELISA试剂盒)-null rod bipolar cells is inactive. Rod bipolar cells in metabotropic glutamate receptor 6 (显示 GRM6 ELISA试剂盒)-null mice were hyperpolarized.

  7. TRPM1 is involved in non-image-forming responses to light and may perform a functional role within photosensitive retinal ganglion cells

  8. This review describes the differential expression of TRPM1-S (short form) and -L (long form) in the mouse retina. TRPM1-L encodes a predicted 1,622 amino acid protein containing six transmembrane domains.

  9. Human TRPM1 mutations are associated with the complete form of congenital stationary night blindness in Japanese patients.

  10. These results demonstrate that TRPM1-L is a component of the ON bipolar cell (BC) transduction channel downstream of mGluR6 in ON BCs.

TRPM1 抗原简介

Antigen Summary

This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with TRPM1

  • transient receptor potential cation channel, subfamily M, member 1 (TRPM1) 抗体
  • transient receptor potential cation channel, subfamily M, member 1a (trpm1a) 抗体
  • transient receptor potential cation channel, subfamily M, member 1 (trpm1) 抗体
  • transient receptor potential cation channel, subfamily M, member 1 (Trpm1) 抗体
  • 4732499L03Rik 抗体
  • AI606771 抗体
  • CSNB1C 抗体
  • Ltrpc1 抗体
  • melastatin 抗体
  • Mlsn1 抗体
  • trpm1 抗体
  • TRPM1b 抗体
  • zgc:158632 抗体

Protein level used designations for TRPM1

transient receptor potential cation channel, subfamily M, member 1 , transient receptor potential melastatin 1b , transient receptor potential cation channel subfamily M member 1-like , long transient receptor potential channel 1 , melastatin-1 , transient receptor potential cation channel subfamily M member 1 , transient receptor potential melastatin family , melastatin 1 , melastatin

GENE ID SPECIES
427494 Gallus gallus
488699 Canis lupus familiaris
527638 Bos taurus
100158130 Sus scrofa
453284 Pan troglodytes
720596 Macaca mulatta
791196 Danio rerio
100021743 Monodelphis domestica
100059740 Equus caballus
100482862 Ailuropoda melanoleuca
100541416 Meleagris gallopavo
100560540 Anolis carolinensis
100594435 Nomascus leucogenys
4308 Homo sapiens
17364 Mus musculus
361586 Rattus norvegicus
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