anti-Transglutaminase 1, Keratinocyte (TGM1) 抗体

The protein encoded by TGM1 is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. 再加上,我们可以发TGM1 试剂盒 (19)TGM1 蛋白 (16)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
TGM1 7051 P22735
TGM1 60335 P23606
TGM1 21816 Q9JLF6

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Cow 非结合性 WB 100 μL Log in to see 5至7个工作日
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豚鼠 非结合性 WB 50 μg Log in to see 29至35个工作日
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非结合性 WB Anti-TGM1 antibody, Western blotting Lane 1: Rat Spleen Tissue Lysate Lane 2: Rat Liver Tissue Lysate Lane 3: HELA Cell Lysate Lane 4: COLO320 Cell Lysate 100 μg Log in to see 26至32个工作日
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豚鼠 非结合性 ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 7至10个工作日
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小鼠 非结合性 ICC, IHC, IP, WB 100 μg Log in to see 7至10个工作日
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大鼠 非结合性 ICC, IHC, IP, WB 100 μg Log in to see 7至10个工作日
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非结合性 ICC, IHC, IP, WB 100 μg Log in to see 7至10个工作日
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小鼠 非结合性 ICC, IHC (p), IP, WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 29至35个工作日
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非结合性 ELISA, WB 50 μg Log in to see 24至29个工作日
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Bat 非结合性 WB   100 μg Log in to see 29至35个工作日
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通过反应活性、应用领域、克隆类型和共轭标记 TGM1 抗体

特性 应用范围 宿主 克隆类型 标记
Human ,
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Rat (Rattus) ,


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Mouse (Murine) ,


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更多抗TGM1的相互作用对抗体

Human Transglutaminase 1, Keratinocyte (TGM1) interaction partners

  1. that the up-regulation of molecular signatures for antimicrobial and innate defense responses is characteristic of skin with a transglutaminase 1 deficiency.

  2. Seven of 10 probands with a compound heterozygous TGM1 genotype had a mutation at either arginine 307 or 315, providing evidence that mutations at these sites are temperature sensitive and highlighting the importance of these residues in the pathogenesis of bathing suit ichthyosis (显示 LBR 抗体)

  3. The results strongly supported the participation of TGM1 in the regulation of gastric cancer development. The authors found evidence that the mechanism of action of TGM1 in regulating gastric cancer cell might involve the Wnt (显示 WNT2 抗体) signaling pathway, as loss of TGM1 expression in gastric cancer cells led to a significant suppression of Wnt (显示 WNT2 抗体) signaling activities.

  4. we identified three novel mutations and one reported mutation in the TGM1 and ABCA12 (显示 ABCA12 抗体) genes, respectively, in affected siblings of five Saudi unrelated families.

  5. Data indicate a decrease in transglutaminases TG1 and TG3 transcripts by about 70% in foreskins from patients with balanitis xerotica obliterans (BXO) BXO in comparison with patients without BXO and an increase in transglutaminase TG2 (显示 TGM2 抗体) mRNA levels by 2.9 fold.

  6. In summary, we have identified three novel sequence variants, one in TGM1 and two in ALOXE3 (显示 ALOXE3 抗体), in three consanguineous families segregating lamellar ichthyosis (显示 LBR 抗体) and congenital ichthyosiform erythroderma types of autosomal recessive congenital ichthyosis (显示 LBR 抗体).

  7. Our results thus indicated that the TGM1 mutation affects the formation of corni fi ed cell envelope by multiple mechanisms and leads to an almost identical clinical phenotype of generalized erythema and scales.

  8. Two siblings with autosomal recessive congenital ichthyosis (显示 LBR 抗体), were found to carry a novel aetiological TGM1 mutation that leads to the synthesis of multiple abnormal transcripts.

  9. mRNA expression of transglutaminase 1 and transglutaminase 3 (显示 TGM3 抗体) was significantly decreased in patients with chronic periodontitis compared with a healthy control group.

  10. In this study, we found that 14 different TGM1 mutations have been identified and reported in 13 individuals with ARCI from 8 families with congental ichthyosis (显示 LBR 抗体), comprising 9 missense mutations, 1 deletion and 1 splice-site mutation .

Cow (Bovine) Transglutaminase 1, Keratinocyte (TGM1) interaction partners

  1. Linkage analysis excluded TGM1 as the cause for ichthyosis (显示 LBR 抗体) phenotype.

Mouse (Murine) Transglutaminase 1, Keratinocyte (TGM1) interaction partners

  1. that the up-regulation of molecular signatures for antimicrobial and innate defense responses is characteristic of skin with a transglutaminase 1 deficiency.

  2. This study investigated the in situ activities of transglutaminase-1 (skin-type) and transglutaminase-2 (显示 TGM2 抗体) (tissue-type) using whole mouse sections of various embryonic developmental stages and neonates.

  3. The R142C mutation of transglutaminase 1 reduces the enzyme stability which is indispensable for development of the stratum corneum and skin barrier function and for postnatal survival of mice.

  4. Molecular deletion of transglutaminase 2 (显示 TGM2 抗体) alone is insufficient to protect Mus (显示 TRPV6 抗体) musculus neurons from oxidative death, but inhibition of transglutaminase 1 and 2 is neuroprotective.

  5. These studies demonstrate that tranglutaminase 2 independent activity exists in the vasculature and that Tgm1 and tgm4 (显示 TGM4 抗体) are expressed in vascular tissues

  6. Mouse models are used to study the role of tissue transglutaminase (tTG (显示 TGM2 抗体))in Huntington's disease; its critical that the level of expression in mouse forebrain be determined. tTG (显示 TGM2 抗体) contributes to the majority of transglutaminase activity in mouse forebrain.

  7. Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase

  8. Tissue-specific stabilization of the cortical actin filament network by intracellular TGase1 activity may play a role in controlling barrier properties of endothelial monolayers

  9. transglutaminase 1

  10. Transglutaminase induces protofibril-like amyloid beta-protein assemblies that are protease-resistant and inhibit long-term potentiation

TGM1 抗原简介

蛋白简介

The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).

Gene names and symbols associated with TGM1

  • transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) (TGM1) 抗体
  • transglutaminase 1 like 4 (tgm1l4) 抗体
  • transglutaminase 1 (TGM1) 抗体
  • transglutaminase 1 (Tgm1) 抗体
  • transglutaminase 1, K polypeptide (Tgm1) 抗体
  • 2310004J08Rik 抗体
  • ARCI1 抗体
  • fa12g12 抗体
  • ICR2 抗体
  • KTG 抗体
  • LI 抗体
  • LI1 抗体
  • TGASE 抗体
  • Tgase1 抗体
  • TGK 抗体
  • TGM1 抗体
  • wu:fa12g12 抗体
  • zgc:112355 抗体

Protein level used designations for TGM1

transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) , TG1-62 , transglutaminase 1 , K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase , TG(K) , TGase K , TGase-1 , epidermal TGase , protein-glutamine gamma-glutamyltransferase K , transglutaminase 1 isoform , transglutaminase K , transglutaminase, keratinocyte , transglutaminase-1 , TGK , transglutaminase 1, K polypeptide , Protein-glutamine gamma-glutamyltransferase K , tranglutaminase 1 , K polypeptide , TG K , TGase 1 , protein-glutamine-gamma-glutamyltransferase , transglutaminase type 1

GENE ID SPECIES
452814 Pan troglodytes
555962 Danio rerio
7051 Homo sapiens
60335 Rattus norvegicus
100724400 Cavia porcellus
100009118 Oryctolagus cuniculus
403630 Canis lupus familiaris
407997 Bos taurus
21816 Mus musculus
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