TCEB1 抗体
(Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011].
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TCEB1 抗体 by 应用范围
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TCEB1 抗体 by 抗原表位
Find TCEB1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
TCEB1 抗体 by 克隆形成能力
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Find TCEB1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
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Quantity
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Application
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Datasheet
Datasheet
Reactivity
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Datasheet
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Reactivity
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Application
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Quantity
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Reactivity
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Latest Publications for our TCEB1 抗体
: "An ID2-dependent mechanism for VHL inactivation in cancer." in: Nature, Vol. 529, Issue 7585, pp. 172-7, (2016) (PubMed).: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).
: "COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32355-65, (2011) (PubMed).
: "GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA." in: Genes & development, Vol. 23, Issue 7, pp. 849-61, (2009) (PubMed).
: "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase." in: The EMBO journal, Vol. 26, Issue 2, pp. 436-47, (2007) (PubMed).
: "RNA polymerase II transcription factor SIII. I. Identification, purification, and properties." in: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25587-93, (1994) (PubMed).
Aliases for TCEB1 抗体
elongin C (Eloc) 抗体elongin C L homeolog (eloc.L) 抗体
elongin C (ELOC) 抗体
transcription elongation factor B (SIII), polypeptide 1b (tceb1b) 抗体
2610043E24Rik 抗体
2610301I15Rik 抗体
AA407206 抗体
AI987979 抗体
AW049146 抗体
eloC 抗体
fb09f09 抗体
SIII 抗体
TCEB1 抗体
wu:fb09f09 抗体
zgc:92635 抗体
zgc:111990 抗体
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