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Titin 抗体

(Titin (TTN))
This gene encodes a large abundant protein of striated muscle. The product of this gene is divided into two regions, a N-terminal I-band and a C-terminal A-band. The I-band, which is the elastic part of the molecule, contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline, glutamate, valine and lysine. The A-band, which is thought to act as a protein-ruler, contains a mixture of immunoglobulin and fibronectin repeats, and possesses kinase activity. An N-terminal Z-disc region and a C-terminal M-line region bind to the Z-line and M-line of the sarcomere, respectively, so that a single titin molecule spans half the length of a sarcomere. Titin also contains binding sites for muscle associated proteins so it serves as an adhesion template for the assembly of contractile machinery in muscle cells. It has also been identified as a structural protein for chromosomes. Alternative splicing of this gene results in multiple transcript variants. Considerable variability exists in the I-band, the M-line and the Z-disc regions of titin. Variability in the I-band region contributes to the differences in elasticity of different titin isoforms and, therefore, to the differences in elasticity of different muscle types. Mutations in this gene are associated with familial hypertrophic cardiomyopathy 9, and autoantibodies to titin are produced in patients with the autoimmune disease scleroderma. [provided by RefSeq, Feb 2012].
Titin 抗体  (AA 1-110) Titin 抗体  (AA 1-110) Titin 抗体 (AA 1-110) (ABIN563282)

TTN 适用: 人 ELISA, WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 2B3 unconjugated

Titin 抗体  (AA 1-110) Titin 抗体  (AA 1-110) Titin 抗体 (AA 1-110) (ABIN563285)

TTN 适用: 人 ELISA, WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 7D3 unconjugated

Titin 抗体  (AA 2670-2703) Titin 抗体  (AA 2670-2703) Titin 抗体 (AA 2670-2703) (ABIN1387283)

TTN 适用: 人, 大鼠, 小鼠 ELISA, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated

Titin 抗体 by 适用

Find Titin 抗体 for a variety of species such as anti-Human Titin, anti-Rat Titin, anti-Mouse Titin. The species listed below are among those available. Click on a link to go to the corresponding products.

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Titin 抗体 by 抗原表位

Find Titin 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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Titin 抗体 by 克隆

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Titin 抗体 by 标记

Find Titin 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Titin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IF, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN563282
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN563285
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, FACS, IF (p), IHC (p)
Validations
  • (4)
Cat. No. ABIN1387283
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7433903
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7172220
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p)
Validations
  • (2)
Cat. No. ABIN6242673
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN563286
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7428053
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN563280
Quantity 50 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7259346
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC (p)
Validations
Cat. No. ABIN1405093
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application FACS, IF (p)
Validations
Cat. No. ABIN1405089
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application FACS, IF (p)
Validations
Cat. No. ABIN1405090
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application FACS, IF (p)
Validations
Cat. No. ABIN1405091
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application FACS, IF (p)
Validations
Cat. No. ABIN2807052
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Titin 抗体

Munkanatta Godage, VanHecke, Samarasinghe, Feng, Hiske, Holcomb, Yang, Jin, Chung, Ahn: "SMYD2 glutathionylation contributes to degradation of sarcomeric proteins." in: Nature communications, Vol. 9, Issue 1, pp. 4341, (2019) (PubMed).

Berkholz, Eberle, Boller, Munz: "siRNA-mediated inhibition of skNAC and Smyd1 expression disrupts myofibril organization: Immunofluorescence and electron microscopy study in C2C12 cells." in: Micron (Oxford, England : 1993), Vol. 108, pp. 6-10, (2019) (PubMed).

Braumann, Thottakara, Stücker, Reischmann-Düsener, Krämer, Groß, Hirt, Doroudgar, Carrier, Friedrich: "S100A4 as a Target of the E3-Ligase Asb2β and Its Effect on Engineered Heart Tissue." in: Frontiers in physiology, Vol. 9, pp. 1292, (2018) (PubMed).

Choi, Park, Yi, Kim: "Novel Mutation of the GNE Gene Presenting Atypical Mild Clinical Feature: A Korean Case Report." in: Annals of rehabilitation medicine, Vol. 39, Issue 3, pp. 494-7, (2015) (PubMed).

Shin, Huang, Kim, Choi: "Differential Protein Expression in Congenital and Acquired Cholesteatomas." in: PLoS ONE, Vol. 10, Issue 9, pp. e0137011, (2015) (PubMed).

Seki, Yuasa, Kusumoto, Kunitomi, Saito, Tohyama, Yae, Kishino, Okada, Hashimoto, Takei, Egashira, Kodaira, Kuroda, Tanaka, Okata, Suzuki, Murata, Fujita, Fukuda: "Generation and characterization of functional cardiomyocytes derived from human T cell-derived induced pluripotent stem cells." in: PLoS ONE, Vol. 9, Issue 1, pp. e85645, (2014) (PubMed).

Aliases for Titin 抗体

titin (TTN) 抗体
titin (Ttn) 抗体
titin (titin) 抗体
titin (TTNLOC100620261) 抗体
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TMD 抗体
UNC-22 抗体
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