电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

TYMS 抗体

(Thymidylate Synthetase (TYMS))
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq, Jul 2008].
TYMS 抗体  (AA 36-313) TYMS 抗体  (AA 36-313) TYMS 抗体 (AA 36-313) (ABIN7436399)

TYMS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

TYMS 抗体  (AA 60-174) TYMS 抗体  (AA 60-174) TYMS 抗体 (AA 60-174) (ABIN6940822)

TYMS 适用: 人 WB, IF, FACS, IHC, ISt, RIA, StM 宿主: 小鼠 Monoclonal TYMS-1884 unconjugated

TYMS 抗体  (AA 111-210) TYMS 抗体  (AA 111-210) TYMS 抗体 (AA 111-210) (ABIN563306)

TYMS 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3A1 unconjugated

TYMS 抗体 by 适用

Find TYMS 抗体 for a variety of species such as anti-Human TYMS, anti-Mouse TYMS, anti-Rat TYMS. The species listed below are among those available. Click on a link to go to the corresponding products.

TYMS 抗体 by 应用范围

Find TYMS 抗体 validated for a specific application such as WB, IF, FACS, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

TYMS 抗体 by 抗体来源

Find TYMS 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

TYMS 抗体 by 抗原表位

Find TYMS 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TYMS 抗体 by 克隆形成能力

Find available monoclonal or polyclonal TYMS 抗体. Click on a link to go to the corresponding products.

TYMS 抗体 by 克隆

Find TYMS 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

TYMS 抗体 by 标记

Find TYMS 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TYMS 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7436399
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS, IHC, ISt, RIA, StM
Validations
  • (7)
Cat. No. ABIN6940822
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, ELISA, IHC (p)
Validations
  • (6)
Cat. No. ABIN563306
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (6)
Cat. No. ABIN1501595
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), IP, ICC
Validations
  • (8)
Cat. No. ABIN2855587
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (5)
Cat. No. ABIN1501589
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IP
Validations
  • (4)
Cat. No. ABIN521191
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS, IHC (p)
Validations
  • (3)
  • (4)
Cat. No. ABIN1882144
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ELISA, IP
Validations
  • (3)
Cat. No. ABIN7172123
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (3)
Cat. No. ABIN7255315
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IF, FACS, ELISA, RIA, Coat
Validations
  • (3)
Cat. No. ABIN6940823
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, EIA
Validations
  • (4)
Cat. No. ABIN452662
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN521189
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, FACS, IHC, ISt, RIA, StM
Validations
  • (2)
Cat. No. ABIN6940818
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IP, FM
Validations
  • (2)
Cat. No. ABIN107488
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TYMS 抗体

Zhao, Zhang, Sun, Zhan, Zhao: "Raltitrexed Inhibits HepG2 Cell Proliferation via G0/G1 Cell Cycle Arrest." in: Oncology research, Vol. 23, Issue 5, pp. 237-48, (2016) (PubMed).

Genovese, Gualandi, Taddia, Marverti, Pirondi, Marraccini, Perco, Pelà, Guerrini, Amoroso, Esposito, Martello, Ponterini, DArca, Costi: "Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides." in: Journal of proteome research, Vol. 13, Issue 11, pp. 5250-61, (2014) (PubMed).

Conradi, Bleckmann, Schirmer, Sprenger, Jo, Homayounfar, Wolff, Rothe, Middel, Becker, Ghadimi, Beissbarth, Liersch: "Thymidylate synthase as a prognostic biomarker for locally advanced rectal cancer after multimodal treatment." in: Annals of surgical oncology, Vol. 18, Issue 9, pp. 2442-52, (2012) (PubMed).

Ma, He, Zhang, Fei, Niu, Wang, Ding, Xu, Chen, Zhu: "DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5639-49, (2012) (PubMed).

Ren, Kim, Koh, Chang, Eom, Yi, Seong, Kim, Bronner, Cho: "Comparative analysis of thymidylate synthase at the protein, mRNA, and DNA levels as prognostic markers in colorectal adenocarcinoma." in: Journal of surgical oncology, Vol. 100, Issue 7, pp. 546-52, (2009) (PubMed).

Sohn, Croxford, Yates, Lucock, Kim: "Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate." in: Journal of the National Cancer Institute, Vol. 96, Issue 2, pp. 134-44, (2004) (PubMed).

Glaser, Staver, Waring, Stender, Ulrich, Davidsen: "Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines." in: Molecular cancer therapeutics, Vol. 2, Issue 2, pp. 151-63, (2003) (PubMed).

Haqqani, Cowling, Maroun, Birnboim: "Characterization of a polyclonal antibody to human thymidylate synthase suitable for the study of colorectal cancer specimens." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 47, Issue 12, pp. 1563-74, (1999) (PubMed).

Schiffer, Clifton, Davisson, Santi, Stroud: "Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site." in: Biochemistry, Vol. 34, Issue 50, pp. 16279-87, (1996) (PubMed).

Aliases for TYMS 抗体

thymidylate synthetase (TYMS) 抗体
thymidylate synthetase (thyA) 抗体
contains intron in T4 phage (td) 抗体
thymidylate synthetase (td) 抗体
ThyE (thyE) 抗体
thymidylate synthase (DDA3937_RS04960) 抗体
thymidylate synthetase L homeolog (tyms.L) 抗体
thymidylate synthase (XBJ1_RS15770) 抗体
thymidylate synthase (EAMY_RS20680) 抗体
thymidylate synthase (Tyms) 抗体
thymidylate synthetase (Tyms) 抗体
ECK2823 抗体
FN1 抗体
HST422 抗体
JW2795 抗体
TMS 抗体
ts 抗体
Ts 抗体
TS 抗体
You are here:
客服