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Sdhaf2 encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. 再加上，我们可以发Sdhaf2 抗体 (10)和数多这个蛋白质的别的产品。
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Loss of SDHAF2 gene is associated with paragangliomas.
The SDHA (显示 SDHA 蛋白), TMEM127, MAX, and SDHAF2 genes contribute to hereditary pheochromocytoma and paraganglioma.
data show that SDHA (显示 SDHA 蛋白) flavination is independent of SDHAF2 in breast cancer cells, employing an alternative mechanism.
FAD (显示 BRCA2 蛋白) interacts noncovalently with SDHA (显示 SDHA 蛋白) in the absence of SDH5
Autosomal dominant susceptibility for Paraganglioma is modified by imprinting and mutations in the SDHAF2 gene cause Paragangliomas only when the mutation is inherited from father.
Loss of heterozygosity was found in more than 50 % of the von Hippel-Lindau-associated pheochromocytomas, and was correlated with a significant decrease (p < 0.05) in both SDHAF2 and SDHD (显示 SDHD 蛋白) mRNA expression, which may be suggestive of a pathogenic role.
New mutation found in SDHAF2 gene in pheochromocytoma/paraganglioma patients.
Data indicate that SDH5 is protected from mitochondrial LON (显示 LONP1 蛋白) (LONM)-mediated degradation in mitochondria by its stable interaction with SDHA (显示 SDHA 蛋白), a state that is dysregulated in hereditary paraganglioma 2 (PGL2).
Data indicate that succinate dehydrogenase (显示 SDHA 蛋白) 5 (SDH5) functions as a critical protein in regulating epithelial-mesenchymal transition (EMT (显示 ITK 蛋白)) by modulating the glycogen synthase kinase (GSK)-3beta-beta-catenin (显示 CTNNB1 蛋白) signaling pathway.
Studies indicate that mutations in the mitochondrial complex II structural subunit genes SDHB (显示 SDHB 蛋白), SDHC (显示 SDHC 蛋白) and SDHD (显示 SDHD 蛋白) and the regulatory subunit gene SDHAF2 in many paraganglioma families.
This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma.
succinate dehydrogenase complex assembly factor 2
, succinate dehydrogenase assembly factor 2, mitochondrial
, SDH assembly factor 2
, Protein EMI5 homolog, mitochondrial
, succinate dehydrogenase subunit 5, mitochondrial