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STMN2 encodes a member of the stathmin family of phosphoproteins. 再加上，我们可以发Stathmin-Like 2 蛋白 (13) 和 Stathmin-Like 2 试剂盒 (1)和数多这个蛋白质的别的产品。
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Cow (Bovine) Polyclonal STMN2 Primary Antibody for WB - ABIN374200
Bahn, Mimmack, Ryan, Caldwell, Jauniaux, Starkey, Svendsen, Emson: Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study. in Lancet 2002
Zeb (显示 KIAA1279 抗体)rafish studies further demonstrated an epistatic interaction between KBP and SCG10 in vivo.
Results provide a starting point for future studies that will investigate the in vivo function of SCG10 orthologues in zebrafish neural development.
RARB (显示 RARB 抗体) and STMN2 polymorphisms were not associated with sporadic CJD (显示 PRNP 抗体) in the Korean population.
PAK4 (显示 PAK4 抗体)-SCG10 signaling occurs in gastric cancer cell invasion.
STMN and SCG10 are similarly targeted by JNK (显示 MAPK8 抗体) but there are clear differences in JNK (显示 MAPK8 抗体) recognition and phosphorylation of the closely related family member, SCLIP (显示 STMN3 抗体).
CaMy1 via SCG10 couples Ca(2 (显示 CA2 抗体)+) signals with the dynamics of microtubules during neuronal outgrowth in the developing brain.
SCG10 is upregulated in the IKAP/Elp1 (显示 IKBKAP 抗体)-deficient familial dysautonomia cerebrum lending support to the concept that SCG10 elevation can alter the microtubule organization and dynamics
Overexpression of SCG10 is associated with Liver Fibrosis.
RGS6 (显示 RGS6 抗体) interacts with this protein and promotes neuronal differentiation; role of the G gamma subunit-like (GGL (显示 GGT5 抗体)) domain of RGS6 (显示 RGS6 抗体)
STMN2 is required for maintaining the anchorage-independent growth state of beta-catenin (显示 CTNNB1 抗体)/TCF (显示 HNF4A 抗体)-activated hepatoma cells
activity at opposite microtubule ends may play role role in regulating growth cone microtubules; ability to promote plus end growth may facilitate microtubule extension; ability to destabilize minus ends may provide tubulin (显示 TUBB 抗体) for net plus end elongation
Review proposes a model reconciling the microtubule regulatory properties of superior cervical ganglion protein 10 with its role as a c-Jun N-terminal kinase 1 (JNK1 (显示 MAPK8 抗体)) effector of regeneration.
SCG10 promotes non-amyloidogenic processing of amyloid precursor protein (显示 APP 抗体) by facilitating its trafficking to the cell surface.
This study demonstrated that axonal injury induces a dynamic regulation of SCG10 protein levels with selective accumulation in proximal axon segments.
JNK (显示 MAPK8 抗体) phosphorylation targets SCG10 for degradation.
SCG10 is not directly implicated in Hirschsprung diseased evelopment
the Rarb (显示 RARB 抗体) region of Mmu14 and Stmn2, but not Cr1 (显示 TDGF1 抗体) or Clu (显示 CLU 抗体) or Picalm (显示 PICALM 抗体) have roles in prion (显示 PRNP 抗体) disease
These findings indicate that the phosphorylation of SCG10 by JNK1 (显示 MAPK8 抗体) is a fundamental mechanism that governs the transition from the multipolar stage and the rate of neuronal cell movement during cortical development.
KBP binds exclusively to microtubule associated or related proteins, specifically SCG10.
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6.
, stathmin-like 2c
, superiorcervical ganglia, neural specific 10
, neuron-specific growth-associated protein
, neuronal growth-associated protein (silencer element)
, superior cervical ganglia, neural specific 10
, superior cervical ganglion-10 protein
, stathmin 2