Solute Carrier Family 34 (Sodium Phosphate), Member 1 (SLC34A1) ELISA试剂盒

SLC34A1 encodes a member of the type II sodium-phosphate cotransporter family.

list all ELISA KIts 基因 基因ID UniProt
小鼠 SLC34A1 SLC34A1 20505  
 SLC34A1 SLC34A1 6569 Q06495
大鼠 SLC34A1 SLC34A1 25548 Q06496

适于 Solute Carrier Family 34 (Sodium Phosphate), Member 1 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Solute Carrier Family 34 (Sodium Phosphate), Member 1 (SLC34A1) interaction partners

  1. Results show that urine pyrophosphate (PPI) levels are increased in Npt2a-/- mice when compared to WT, possibly to protect from renal mineralization in the setting of hyperphosphaturia. However, the presence of two hypomorphic Enpp1asj/asj (显示 ARSJ ELISA试剂盒) alleles decreases urine PPi and worsens renal calcium phosphate deposit formation in Npt2a-/- mice.

  2. Npt2a-/- mice respond differently to dietary phosphate when compared to WT mice

  3. observed a marked decrease of renal gene expression and urinary excretion of osteopontin (显示 SPP1 ELISA试剂盒) in Npt2a(-/-) mice

  4. Analysis of calcium and phosphate metabolism in Slc34a1-knockout mice highlighted the effect of phosphate depletion and fibroblast growth factor-23 suppression on the development of the idiopathic infantile hypercalcemia phenotype.

  5. AC6 (显示 ADCY6 ELISA试剂盒) in the proximal tubule modulates cAMP formation, Npt2a trafficking, and urinary phosphate excretion, which are highlighted by renal phosphate wasting in AC6 (显示 ADCY6 ELISA试剂盒)(-/-) mice

  6. Downregulation of renal Npt2a expression through induction of plasma iPTH levels alters Pi homeostasis during LPS (显示 TLR4 ELISA试剂盒)-induced acute inflammation.

  7. serine 249 of ezrin (显示 EZR ELISA试剂盒) can play important roles in the regulation of the complex formation and membrane localization of NaPi-IIa.

  8. Npt2a protein expression in PTH (显示 PTH ELISA试剂盒)-D1 mice was decreased relative to control animals, whereas levels of Na-K, NHERF-1 (显示 SLC9A3R1 ELISA试剂盒), and PTH (显示 PTH ELISA试剂盒) receptor remained unchanged.

  9. The authors conclude that the polyclonal antiserum is specific toward NaPi-IIa in the kidney, but in the brain, immunolabeling is caused by a cross-reaction of the antiserum with an unknown cytosolic protein that is not present in the kidney.

  10. reduced intestinal Pi absorption in VDR (显示 CYP27B1 ELISA试剂盒) (-/-) mice does not seem to be the only factor that causes hypophosphatemia; reduced Npt2a, Npt2c (显示 SLC34A3 ELISA试剂盒), or PiT-2 (显示 SLC20A2 ELISA试剂盒) protein levels during development might also cause hypophosphatemia and rickets in VDR (显示 CYP27B1 ELISA试剂盒) (-/-) mice.

Human Solute Carrier Family 34 (Sodium Phosphate), Member 1 (SLC34A1) interaction partners

  1. Biallelic mutations in CYP24A1 (显示 CYP24A1 ELISA试剂盒) or SLC34A1 were associated with infantile idiopathic hypercalcemia with vitamin D hypersensitivity

  2. FGFR1c and PTHR (显示 PTHLH ELISA试剂盒) signaling pathways converge on NHERF1 (显示 SLC9A3R1 ELISA试剂盒) to inhibit PTH (显示 PTH ELISA试剂盒)- and FGF23 (显示 FGF23 ELISA试剂盒)-sensitive phosphate transport and down-regulate NPT2A.

  3. The identification of autosomal-recessive SLC34A1 mutations in infants with idiopathic infantile hypercalcemia now demonstrates a crucial role of renal sodium-phosphate cotransporter 2A for calcium metabolism as well as phosphate balance in humans

  4. Estrogen downregulated NaPi-IIa only in U20S cells expressing both ERalpha (显示 ESR1 ELISA试剂盒) and ERbeta (显示 ESR2 ELISA试剂盒), but not in cells expressing either receptor alone.

  5. A novel homozygous mutation in the gene encoding the renal sodium-dependent phosphate transporter SLC34A1 was identified in two siblings with hypercalcemia, hypercalciuria, hypophosphatemia, low parathyroid hormone (PTH (显示 PTH ELISA试剂盒)), and nephrocalcinosis.

  6. B-RAF (显示 SNRPE ELISA试剂盒) increases the cell surface protein (显示 CD28 ELISA试剂盒) abundance and activity of the type II Na+-coupled phosphate transporters NaPi-IIa and NaPi-IIb (显示 SLC34A2 ELISA试剂盒).

  7. JAK2 (显示 JAK2 ELISA试剂盒) contributes to the regulation of phosphate transporter NaPiIIa

  8. Results indicate that the PDZ1 domain is critical for NHERF1 (显示 SLC9A3R1 ELISA试剂盒)-NPT2a interaction in humans and for the control of NPT2a expression at the plasma membrane.

  9. Our cases suggest a contiguous gene deletion syndrome including NSD1 (显示 NSD1 ELISA试剂盒) and SLC34A1 and provide a potential genetic basis for idiopathic infantile hypercalcemia.

  10. Results suggest that a 31-kDa nuclear protein (显示 RDBP ELISA试剂盒) from kidney-derived cells binds to the C/EBP (显示 CEBPA ELISA试剂盒)-like region of the type II Na/Pi-cotransporter promoter.

Solute Carrier Family 34 (Sodium Phosphate), Member 1 (SLC34A1) 抗原简介

Antigen Summary

This gene encodes a member of the type II sodium-phosphate cotransporter family. Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SLC34A1

  • solute carrier family 34 (sodium phosphate), member 1 (SLC34A1) 抗体
  • solute carrier family 34 (sodium phosphate), member 1 (Slc34a1) 抗体
  • solute carrier family 34 (type II sodium/phosphate contransporter), member 1 (SLC34A1) 抗体
  • solute carrier family 34 (type II sodium/phosphate contransporter), member 1 (Slc34a1) 抗体
  • FRTS2 抗体
  • NaPi-2 抗体
  • NAPI-3 抗体
  • NaPi-IIa 抗体
  • NaPi2A 抗体
  • NPHLOP1 抗体
  • NPT2 抗体
  • Npt2a 抗体
  • NPTIIa 抗体
  • SLC11 抗体
  • SLC17A2 抗体
  • SLC34A1 抗体

Protein level used designations for SLC34A1

solute carrier family 34 (sodium phosphate), member 1 , Na/Pi cotransporter NaPi-IIa , Na(+)-dependent phosphate cotransporter 2A , Na(+)/Pi cotransporter 2A , Na/Pi cotransporter , naPi-2a , naPi-7 , renal Na+/Pi transporter , sodium-dependent phosphate transport protein 2A , sodium-phosphate transport protein 2A , sodium/phosphate cotransporter 2A , solute carrier family 17 (sodium/hydrogen exchanger), member 2 , solute carrier family 34 member 1 , type IIa Na+/Pi-cotransporter , naPi-6 , renal sodium-dependent phosphate transporter type II , Na+/phosphate cotransporter , Na+-phosphate cotransporter type II , renal sodium-dependent phosphate transporter , sodium/phosphate co-transporter , solute carrier family 17 (sodium phosphate), member 2 , solute carrier family 17 (sodium/hydrogen exchanger) member 2 , solute carrier family 34, member 1

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20505 Mus musculus
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