anti-Solute Carrier Family 31 (Copper Transporters), Member 1 (SLC31A1) 抗体

The protein encoded by SLC31A1 is a high-affinity copper transporter found in the cell membrane. 再加上,我们可以发Solute Carrier Family 31 (Copper Transporters), Member 1 试剂盒 (18)Solute Carrier Family 31 (Copper Transporters), Member 1 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SLC31A1 1317 O15431
SLC31A1 171135 Q9JK41
SLC31A1 20529 Q8K211

antibodies-online.cn销售最多的anti-Solute Carrier Family 31 (Copper Transporters), Member 1 抗体

Showing 10 out of 82 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB WB Suggested Anti-Slc31a1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Liver 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
非结合性 ICC, IHC (fro), IF, IHC (p), IHC, WB The photo on the left is antibody staining of hCTR1 overexpressing cell line.  The photo on the right is antibody plus peptide competition staining. Panel 1: human CTR1 staining of breast cancer tissue. Panel 2: human CTR1-antigen competition in breast cancer tissue. 0.1 mL Log in to see 25至31个工作日
¥3,655.56
详细
小鸡 非结合性 IHC (p) Anti-CTR1 antibody  ABIN960807 IHC staining of human colon, malt. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-CTR1 antibody  ABIN960807 IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 29至35个工作日
¥4,324.07
详细
非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
详细
非结合性 IHC (p) Anti-CTR1 antibody  ABIN960806 IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-CTR1 antibody  ABIN960806 IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 29至35个工作日
¥4,324.07
详细
非结合性 IHC (p) 50 μg Log in to see 30至36个工作日
¥3,985.39
详细
非结合性 IHC (p) 50 μg Log in to see 30至36个工作日
¥3,985.39
详细
小鼠 非结合性 IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: SLC31A1/CTR1 Antibody (5E6.1B4) [NBP2-36573] - HepG2 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti SLC31A1/CTR1 (5E6.1B4) NBP2-36573 at a 1:50 dilution overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:500 dilution. Actin was detected with Phalloidin 568 (Red) at a 1:200 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective. Immunohistochemistry-Paraffin: SLC31A1/CTR1 Antibody (5E6.1B4) [NBP2-36573] - IHC-P analysis of a formalin fixed and paraffin embedded tissue section of human urinary bladder transitional cell carcinoma (NBP2-30234) using purified CTR1/SLC31A1 antibody clone 5E6.1B4 at 5 ug/ml concentration. 0.1 mg Log in to see 25至31个工作日
¥2,594.28
详细
非结合性 WB Western blot analysis of extracts of various cells, using SLC31A1 antibody. 100 μL Log in to see 34至38个工作日
¥2,882.69
详细
非结合性 ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: SLC31A1/CTR1 Antibody [NBP1-84405] - Immunohistochemical staining of human small intestine shows moderate cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: SLC31A1/CTR1 Antibody [NBP1-84405] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli & centrosome. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
详细

通过反应活性、应用领域、克隆类型和共轭标记 SLC31A1 抗体

特性 应用范围 宿主 克隆类型 标记
Human , ,
,
,
, , , , , , , , , , , , , , , ,
Rat (Rattus) , ,


, , , , , , , , , ,
Mouse (Murine) , ,


, , , , , , , , , ,

引用最多的anti-Solute Carrier Family 31 (Copper Transporters), Member 1 抗体

  1. Human Polyclonal SLC31A1 Primary Antibody for ICC, IHC (fro) - ABIN151866 : Holzer, Howell: The internalization and degradation of human copper transporter 1 following cisplatin exposure. in Cancer research 2006 (PubMed)
    Show all 12 Pubmed References

更多抗Solute Carrier Family 31 (Copper Transporters), Member 1的相互作用对抗体

Arabidopsis thaliana Solute Carrier Family 31 (Copper Transporters), Member 1 (SLC31A1) interaction partners

  1. Data indicate that cadmium (Cd) elicits SPL7-dependent copper (Cu) deficiency responses by altering expression of COPT1, COPT2 (显示 SLC31A2 抗体), COPT6, CSD1, CSD2 (显示 TGFB1 抗体), miRNA398 b/c precursors and FSD1 (显示 FSD1 抗体).

  2. Col (显示 HDAC1 抗体)-0, high-affinity copper transporter COPT1-overexpressing (C1(OE)) seedlings and T-DNA COPT1 insertion mutant (copt1) differ in their copper-transport activity. C1(OE) showed a fivefold higher Cu-induced K(+) efflux at the root tip compared with Col (显示 HDAC1 抗体)-0.

Human Solute Carrier Family 31 (Copper Transporters), Member 1 (SLC31A1) interaction partners

  1. we assessed the role of miR (显示 MLXIP 抗体)-21 in mediating renal cell carcinoma (显示 MOK 抗体) chemoresistance and further showed that miR (显示 MLXIP 抗体)-21 silencing significantly (1) increased chemosensitivity of paclitaxel, 5-fluorouracil, oxaliplatin, and dovitinib; (2) decreased expression of multi-drug resistance genes; and (4) increased SLC22A1/OCT1, SLC22A2/OCT2 (显示 SLC22A2 抗体), and SLC31A1/CTR1 platinum influx transporter expression

  2. Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2 (显示 SLC31A2 抗体)

  3. It has been demonstrated in ovarian cancer cells that cisplatin resistance and uptake correlates with reduced CTR1 and LRRC8A (显示 LRRC8A 抗体) protein expression/activity and a concomitant upregulation in cisplatin exporting transporters (ATP7A (显示 ATP7A 抗体), ATP7B (显示 ATP7B 抗体)), which implies that the resistant cells have a reduced ability to accumulate cisplatin and activate proapoptotic transporters for osmolytes.

  4. CTR1 recycling via clathrin-mediated and Rab11 pathways enable cells to dynamically modulate copper entry

  5. C-Terminus of Human Copper Importer Ctr1 Acts as a Binding Site and Transfers Copper to Atox1 (显示 ATOX1 抗体)

  6. Studied the interaction of CTR1 and CTR2 (显示 SLC31A2 抗体) in fully malignant HEK293T and OVCAR8 human ovarian cancer cells using a CRISPR-Cas9 knock out system.

  7. High CTR1 Expression is associated with poor response to chemotherapy in Muscle-invasive Bladder Cancer.

  8. Gene silencing of either CTR1 or DMT1 (显示 DMRT1 抗体) did not affect copper accumulation in cells, but deficiency in both CTR1 and DMT1 (显示 DMRT1 抗体) resulted in a complete inhibition of copper uptake.

  9. Two methionine residues in the MXXXM motif of of the CTR1 second transmembrane domain are important for binding to silver.

  10. CTR1, ATP7A (显示 ATP7A 抗体), and lysyl oxidase (显示 LOX 抗体) were upregulated in the lung tissues and pulmonary arteries of mice with hypoxia-induced pulmonary hypertension and pulmonary arterial smooth muscle cells.

Zebrafish Solute Carrier Family 31 (Copper Transporters), Member 1 (SLC31A1) interaction partners

  1. Studies show that zebrafish ctr1 is an essential gene for development.

Mouse (Murine) Solute Carrier Family 31 (Copper Transporters), Member 1 (SLC31A1) interaction partners

  1. Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2 (显示 SLC31A2 抗体)

  2. studies identify a new processing event and the key protease that cleaves the Ctr1 metal-binding ectodomain, which functions to regulate cellular Cu(+) and cisplatin acquisition

  3. CTR1, ATP7A (显示 ATP7A 抗体), and lysyl oxidase (显示 LOX 抗体) were upregulated in the lung tissues and pulmonary arteries of mice with hypoxia-induced pulmonary hypertension and pulmonary arterial smooth muscle cells.

  4. conclude that Y103 is required for the internalization of hCTR1 in response to Cu, that this occurs by a mechanism other than phosphorylation and that mutation of Y103 modulates the interaction with IRS-4 (显示 IRS4 抗体)

  5. A key regulatory mechanism for mammalian copper transport is through Ctr2 (显示 SLC31A2 抗体)-dependent accumulation of a Ctr1 variant lacking the copper- and cisplatin-binding ecto (显示 TRIM33 抗体)-domain.

  6. conclude that Cu acquired from CTR1 is required for signaling in pathways regulated by RTKs that play major roles in development and cance

  7. There was little difference in rates/kinetics of uptake of copper in the Ctr1+/+ and -/- cells. Endocytosis was not involved.

  8. basal expression of Ctr1 is regulated by HIF2alpha (显示 EPAS1 抗体); however, the induction by hypoxia is a HIF2alpha (显示 EPAS1 抗体)-independent event

  9. Structure-functional organization of eukaryotic high-affinity copper importer CTR1 determines its ability to transport copper, silver and cisplatin

  10. Data show apical localization of Ctr1 in intestinal epithelia and suggest that increased Ctr1 apical localization in response to dietary copper limitation may represent an adaptive response to modulate Ctr1 availability at the site of copper absorption.

Solute Carrier Family 31 (Copper Transporters), Member 1 (SLC31A1) 抗原简介

蛋白简介

The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper.

Gene names and symbols associated with SLC31A1

  • solute carrier family 31 (copper transporters), member 1 (SLC31A1) 抗体
  • copper transporter 1 (LOC100281410) 抗体
  • copper transporter 1 (LOC100286321) 抗体
  • solute carrier family 31 (copper transporter), member 1 (slc31a1) 抗体
  • copper transporter 1 (COPT1) 抗体
  • high-affinity copper uptake protein (CTR1) 抗体
  • solute carrier family 31 (copper transporter), member 1 (SLC31A1) 抗体
  • solute carrier family 31 (copper transporter), member 1 (Slc31a1) 抗体
  • solute carrier family 31 (copper transporters), member 1 (slc31a1) 抗体
  • solute carrier family 31, member 1 (Slc31a1) 抗体
  • 4930445G01Rik 抗体
  • AI787263 抗体
  • AU016967 抗体
  • copper transporter 1 抗体
  • COPT1 抗体
  • ctr-1 抗体
  • Ctr1 抗体
  • hctr1 抗体
  • K19M22.24 抗体
  • LRRGT00200 抗体
  • Slc31a1 抗体
  • Xctr1 抗体
  • zgc:76839 抗体

Protein level used designations for SLC31A1

solute carrier family 31 (copper transporters), member 1 , high affinity copper uptake protein 1 , Copper transporter 1 , copper transporter 1 , solute carrier family 31 member 1 , copper transport 1 homolog , Copper uptake transporter 1 , liver regeneration-related protein LRRGT00200 , rCTR1 , high affinity copper uptake protein , solute carrier family 13 (sodium/sulphate symporters), member 1

GENE ID SPECIES
417268 Gallus gallus
464670 Pan troglodytes
481678 Canis lupus familiaris
518976 Bos taurus
706058 Macaca mulatta
100172583 Pongo abelii
100281410 Zea mays
100286321 Zea mays
407919 Xenopus (Silurana) tropicalis
836020 Arabidopsis thaliana
397186 Sus scrofa
1317 Homo sapiens
171135 Rattus norvegicus
403028 Danio rerio
20529 Mus musculus
anti-Solute Carrier Family 31 (Copper Transporters), Member 1 (SLC31A1) 抗体 精选生产商
您还需要查找其他产品吗?