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The protein encoded by SLC20A1 is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. 再加上，我们可以发SLC20A1 抗体 (36) 和 SLC20A1 蛋白 (7)和数多这个蛋白质的别的产品。
Cysteine substitution at some sites also altered the apparent affinity for Pi and cation (Na(+)/Li(+)) and substrate (phosphate/arsenate) selectivity, further underscoring the importance of this linker in defining PiT-1 (显示 POU1F1 ELISA试剂盒) transport characteristics.
indoxyl sulfate promotes Pit-1 (显示 POU1F1 ELISA试剂盒) expression in part by activation of the JNK (显示 MAPK8 ELISA试剂盒) pathway in vascular smooth muscle cells
Ox-LDL induces an osteogenic change in human aortic valve interstitial cells marked by the induction of PiT-1 (显示 POU1F1 ELISA试剂盒).
Overexpression of SLC20A1 promotes apoptosis and mineralization by altering the level of Akt-1 (显示 AKT1 ELISA试剂盒).
Allelic variations in SLC20A1 were associated with the levels of Sodium-lithium countertransport.
the human PiT2 (显示 SLC20A2 ELISA试剂盒) histidine, H(502), and the human PiT1 (显示 POU1F1 ELISA试剂盒) glutamate (显示 GRIN1 ELISA试剂盒), E(70),--both conserved in eukaryotic PiT (显示 IRF6 ELISA试剂盒) family members--are critical for P(i) transport function
Identification of a novel transport-independent function of PiT1/SLC20A1 in the regulation of TNF (显示 TNF ELISA试剂盒)-induced apoptosis.
propose that region A of Pit1 (显示 POU1F1 ELISA试剂盒) confers competence for viral entry by influencing the topology of the authentic binding site in the membrane and hence its accessibility to a viral envelope protein
Two highly conserved glutamate (显示 GRIN1 ELISA试剂盒) residues critical for sodium-dependent phosphate transport are revealed by uncoupling transport function from retroviral receptor function.
Our results link low-grade IL-8 (显示 IL8 ELISA试剂盒)-mediated cartilaginous inflammation in OA to altered chondrocyte differentiation and disease progression through PiT-1 (显示 POU1F1 ELISA试剂盒) expression and sodium-dependent Pi uptake mediated by CXCR1 (显示 CXCR1 ELISA试剂盒) signaling.
Phosphate uptake through Pit-1 (显示 POU1F1 ELISA试剂盒) is essential for vascular smooth muscle cell calcification and phenotypic modulation in response to elevated phosphate.
propose the novel idea that PiT-1 (显示 POU1F1 ELISA试剂盒) is central to the regulation of endocytosis and autophagy in the yolk sac (显示 ADCY10 ELISA试剂盒) visceral endoderm
Pi uptake-dependent and -independent functions of PiT-1 (显示 POU1F1 ELISA试剂盒) are important for vascular smooth muscle cell processes mediating vascular calcification.
Mechanistically, PiT-1 (显示 POU1F1 ELISA试剂盒) and PiT-2 (显示 SLC20A2 ELISA试剂盒) seem to serve redundant roles in phosphate-induced calcification of vascular smooth muscle cells.
Data indicate that mice lacking SLC20A1 (PiT1) develop a profound underproduction anemia characterized by mild macrocytosis, dyserythropoiesis, increased apoptosis, and a near complete block in terminal erythroid differentiation.
Incisor enamel formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a1.
that cellular ATP synthesis consequent to P(i) uptake via Pit-1 (显示 POU1F1 ELISA试剂盒) plays an important role in chondrocyte apoptosis and mineralization, and that chondrogenesis is ATP-dependent.
Data illustrate a specific in vivo role for PiT1 (显示 POU1F1 ELISA试剂盒) by uncovering it as being a critical gene for normal developmental liver growth.
investigation of function of piT-1 (显示 POU1F1 ELISA试剂盒) using transgenic rats: overexpression of piT-1 (显示 POU1F1 ELISA试剂盒) decreased alkaline phosphatase activity in osteoblasts without influencing bone matrix mineralization or skeletal development
Inorganic phosphate effects on Glvr-1 and -2 up-regulation require the presence of calcium and involve ERK (显示 EPHB2 ELISA试剂盒) signalling pathways.
The protein encoded by this gene is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. The encoded protein is also a retroviral receptor, causing human cells to be susceptible to infection by gibbon ape leukemia virus, simian sarcoma-associated virus, feline leukemia virus subgroup B, and 10A1 murine leukemia virus.
solute carrier family 20 (phosphate transporter), member 1
, sodium-dependent phosphate transporter 1
, solute carrier family 20 member 1
, sodium-dependent phosphate transporter 1-B
, solute carrier family 20 member 1-B
, gibbon ape leukemia virus receptor 1
, leukemia virus receptor 1 homolog
, phosphate transporter 1
, feline leukemia virus subtype-B receptor
, leukemia virus-b receptor