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Proton-linked monocarboxylate transporter. 再加上，我们可以发SLC16A4 蛋白 (4)和数多这个蛋白质的别的产品。
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This study showed that mouse MCT1 (显示 MCTS1 抗体), MCT2 (显示 SLC16A7 抗体), and MCT4 (显示 SLC16A3 抗体) are expressed in the PNS. While DRG neurons express MCT1 (显示 MCTS1 抗体), myelinating Schwann cells.
Expression of cerebral MCT (显示 MCAT 抗体) isoforms can be modulated by alterations of peripheral metabolism, suggesting that the adult brain is sensitive and adapts to new metabolic states.
MCT1 (显示 CMA1 抗体) inhibitor AZD3965 increased MCT4-dependent accumulation of intracellular lactate, inhibiting monocarboxylate influx and efflux.
The reversible H(+)/lactate(-) symporter MCT4 cotransports lactate and proton, leading to the net extrusion of lactic acid in glycolytic tumors. A model of its role in pH control in tumor cells is described. Review.
Increased miR (显示 MLXIP 抗体)-210 and concomitant decreased ISCU (显示 ISCU 抗体) RNA levels were found in ~40% of tumors and this was significantly associated with HIF-1alpha (显示 HIF1A 抗体) and CAIX (显示 CA9 抗体), but not MCT1 (显示 CMA1 抗体) or MCT4, over-expression.
High expression of MCT4 is associated with inflammation in arsenite-induced liver carcinogenesis.
The loss expression of Cav-1 on CAFs and the up-regulation of MCT4 may be the possible mechanisms of CAFs in tumorigenesis.
MCT1 (显示 CMA1 抗体) and MCT4 expression levels were associated with worse prognosis and shorter overall survival.
We demonstrated that the expression levels of glycolysis-related proteins glucose transporter 1 (显示 SLC2A1 抗体), hexokinase II, carbonic anhydrase IX (显示 CA9 抗体), and monocarbonylate transporter 4 differ between thyroid cancer subtypes and are correlated with poorer prognosis
Data suggest that inhibition of mnocarboxylate transporters MCT1 (显示 CMA1 抗体) and MCT4 may have clinical relevance in pancreatic ductal adenocarcinoma (PDAC).
MCT1 (显示 CMA1 抗体) inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 (显示 CMA1 抗体) and MCT4 via disruption of pyruvate rather than lactate export.
MCT1 (显示 CMA1 抗体) expression was not clearly associated with overall or disease-free survival. MCT4 and CD147 expression correlate with worse prognosis across many cancer types. These results warrant further investigation of these associations
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
, solute carrier family 16, member 4
, monocarboxylate transporter 5
, monocarboxylate transporter 6
, solute carrier family 16 member 5
, MCT 4
, MCT 5
, monocarboxylate transporter 4
, solute carrier family 16 (monocarboxylic acid transporters), member 4