anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) 抗体

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. 再加上,我们可以发SCNN1A 试剂盒 (13)SCNN1A 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SCNN1A 6337 P37088
SCNN1A 20276 Q61180
SCNN1A 25122 P37089
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Showing 10 out of 145 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 FACS, ICC, IF, WB Western Blot: epithelial Sodium Channel alpha Antibody [ABIN2614667] - Analysis of 25 ug of Daudi (lane 1) and mouse brain (lane 2) cell lysates onto an SDS polyacrylamide gel. 0.1 mg Log in to see 7至9个工作日
$447.56
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非结合性 FACS, IF, IHC (p), WB Western blot analysis of SCNN1A Antibody (Center) (ABIN652752) in WiDr cell line lysates (35 µg/lane). SCNN1A (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with SCNN1A Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded rat kidney labeled with Anti-Alpha-ENaC Polyclonal Antibody, Unconjugated (ABIN682243) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3至7个工作日
$307.45
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小鼠 非结合性 ICC, IF, IHC, WB ENaC alpha, rat kidney tissue. 100 μg Log in to see 2至3个工作日
$394.90
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Hamster 非结合性 ICC, IF, IP, IHC, WB ENaC beta, rat kidney tissue. 100 μg Log in to see 2至3个工作日
$394.90
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非结合性 EIA, WB   0.4 mL Log in to see 12至15个工作日
$375.38
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小鼠 HRP ICC, IF, IHC, WB Western blot analysis of Rat kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. Western blot analysis of Mouse kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. 100 μg Log in to see 2至3个工作日
$433.40
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小鼠 FITC ICC, IF, IHC, WB Western blot analysis of Rat kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. Western blot analysis of Mouse kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. 100 μg Log in to see 2至3个工作日
$437.80
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小鼠 Alkaline Phosphatase (AP) ICC, IF, IHC, WB Western blot analysis of Rat kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. Western blot analysis of Mouse kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. 100 μg Log in to see 2至3个工作日
$440.00
详细
小鼠 Biotin ICC, IF, IHC, WB Western blot analysis of Rat kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. Western blot analysis of Mouse kidney tissue lysates showing detection of ENaC protein using Rabbit Anti-ENaC Polyclonal Antibody . Primary Antibody: Rabbit Anti-ENaC Polyclonal Antibody  at 1:1000. 100 μg Log in to see 2至3个工作日
$442.20
详细

通过反应活性、应用领域、克隆类型和共轭标记 SCNN1A 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-SCNN1A 抗体

  1. Mouse (Murine) Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN863202 : Jia, Liu, Sun, Kakizoe, Guan, Zhang, Zhou, Yang: mPGES-1-derived PGE2 mediates dehydration natriuresis. in American journal of physiology. Renal physiology 2013 (PubMed)
    Show all 22 Pubmed References

  2. Hamster Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN863204 : Gu: Effect of [Cl(-)]i on ENaC activity from mouse cortical collecting duct cells. in Journal of cellular physiology 2008 (PubMed)
    Show all 22 Pubmed References

  3. Hamster Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN863203 : Dyka, May, Enz: Subunits of the epithelial sodium channel family are differentially expressed in the retina of mice with ocular hypertension. in Journal of neurochemistry 2005 (PubMed)
    Show all 22 Pubmed References

  4. Human Polyclonal SCNN1A Primary Antibody for FACS, ICC - ABIN261466 : Williams, Chamarthi, Goodarzi, Pojoga, Sun, Garza, Raby, Adler, Hopkins, Brown, Jeunemaitre, Ferri, Fang, Leonor, Cui, Guo, Taylor, Ida Chen, Xiang, Raffel, Buchanan, Rotter, Williams, Shi: Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension. in American journal of hypertension 2012 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal SCNN1A Primary Antibody for IF (p), IHC (p) - ABIN682243 : Yamamoto, Hotta, Maeda, Kataoka, Maeda, Hamakawa, Sasaki, Yasui, Asai, Kimura: Mineralocorticoid receptor stimulation induces urinary storage dysfunction via upregulation of epithelial sodium channel expression in the rat urinary bladder epithelium. in Journal of pharmacological sciences 2016 (PubMed)

更多抗SCNN1A的相互作用对抗体

Rabbit Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) interaction partners

Human Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) interaction partners

  1. The mRNA and alpha-ENaC protein were overexpressed in platelets from hypertensive subjects versus control subjects.

  2. The derlin-1 (显示 DERL1 抗体) pathway therefore may represent a significant early checkpoint in the recognition and degradation of ENaC in mammalian cells.

  3. Data show that the expression of aquaporin (AQP) 1 (显示 AQP1 抗体), AQP3 (显示 AQP3 抗体), AQP5 (显示 AQP5 抗体), epithelial Na+ channel (ENaC) and sodium potassium ATPase (显示 DNAH8 抗体) (Na-K-ATPase (显示 ATP1A1 抗体)) are altered in patients with acute respiratory failure (ARF (显示 CDKN2A 抗体)) due to diffuse alveolar damage (DAD), and the cause of DAD does not seem to influence the level of impairment of these channels.

  4. The data indicate that the Lhs1 chaperone selectively recognizes an immature form of alphaENaC, one which has failed to correctly assemble with the other channel subunits via its transmembrane domain.

  5. LEFTY2 (显示 LEFTY2 抗体) regulates the expression and activity of ENaC in endometrial epithelial cells via SGK1 (显示 SGK1 抗体).

  6. Carriage of the p.W493R-SCNN1A polymorphism has been identified as a risk factor for bronchiectasis, but it is not invariably associated with the phenotype of a hyperactive ENaC channel in the lung.

  7. although subgroup analysis showed alpha-ENaC T663A polymorphism was associated with essential hypertension in North American individuals, these meta-analysis results did not confirm such association overall; conclude that Alpha-ENaC T663A polymorphism might not be a risk factor for essential hypertension

  8. Four nonsynonymous amino acid variants in SCNN1A in nonwhite Cystic fibrosis (显示 S100A8 抗体) patients with non-diagnostic CFTR (显示 CFTR 抗体) genotypes was identified.

  9. The rs4149570 and rs7956915 polymorphisms of SCNN1A might play important roles in the susceptibility to respiratory distress syndrome, particularly in term infants.

  10. These results indicate that ENaC functions as a sensor for external Cd2 (显示 CD2 抗体)+.

Xenopus laevis Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) interaction partners

Mouse (Murine) Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) interaction partners

  1. The derlin-1 (显示 DERL1 抗体) pathway therefore may represent a significant early checkpoint in the recognition and degradation of ENaC in mammalian cells.

  2. ENaC activity is regulated by calpain-2 (显示 CAPN2 抗体) proteolysis of MARCKS (显示 MARCKS 抗体).

  3. nonselective cation channels ( channels consist of at least one alpha-ENaC and one or more acid-sensing ion channel (显示 ACCN2 抗体) 1a (ASIC1a (显示 ACCN2 抗体)) proteins.

  4. ENaC and ROMK (显示 KCNJ1 抗体) channel activity in kidney tubules are inhibited in TgWnk4(pseudoaldosteronism type II) mice. Wnk4 (显示 WNK4 抗体)(PHAII)-induced inhibition of ENaC and ROMK (显示 KCNJ1 抗体) may contribute to the suppression of K(+) secretion in the tubules.

  5. Exosomal GAPDH (显示 GAPDH 抗体) from Proximal Tubule Cells Regulate ENaC Activity

  6. depletion of Kir4.1 (显示 KCNJ10 抗体) stimulates the expression of ENaCbeta (显示 SCNN1B 抗体) and -gamma subunits in the cortical collecting duct

  7. LEFTY2 (显示 LEFTY2 抗体) regulates the expression and activity of ENaC in endometrial epithelial cells via SGK1 (显示 SGK1 抗体).

  8. reducing ENaC expression in the connecting tubule induces clear pseudohypoaldosteronism type 1 symptoms during high dietary potassium loading

  9. The findings demonstrated a substantial role of mitochondrial dysfunction in mediating the downregulation of NKCC2 (显示 SLC12A1 抗体) and ENaCalpha in obstructive kidney disease, possibly via iNOS (显示 NOS2 抗体)-derived nitric oxide and BNP (显示 BNC2 抗体).

  10. PCSK9 (显示 PCSK9 抗体)(-/-) mice display normal sodium balance and blood pressure regulation despite an increase of cleaved alphaENaC under basal condition

Guinea Pig Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) interaction partners

  1. Different subunits of ENaC expressed in various cell regions of the cochlea and endolymphatic sac (显示 ADCY10 抗体) in distinct patterns may form the functional sodium channel to regulate the endolymph and maintain homeostasis in inner ear.

SCNN1A 抗原简介

蛋白简介

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with SCNN1A

  • sodium channel epithelial 1 alpha subunit (SCNN1A) 抗体
  • sodium channel, non voltage gated 1 alpha subunit L homeolog (scnn1a.L) 抗体
  • sodium channel epithelial 1 delta subunit (SCNN1D) 抗体
  • sodium channel, nonvoltage-gated 1 alpha (Scnn1a) 抗体
  • sodium channel epithelial 1 alpha subunit (Scnn1a) 抗体
  • alphaxENaC 抗体
  • besc2 抗体
  • ENAC 抗体
  • enaca 抗体
  • ENaCalpha 抗体
  • mENaC 抗体
  • SCNEA 抗体
  • Scnn1 抗体
  • SCNN1A 抗体

Protein level used designations for SCNN1A

alpha-subunit renal epithelial sodium channel , amiloride-sensitive sodium channel subunit alpha , sodium channel, nonvoltage-gated 1 alpha , alpha ENaC , epithelial sodium channel alpha subunit , epithelium sodium channel alpha subunit , sodium channel, nonvoltage-gated 1, alpha , amiloride-sensitive sodium channel alpha subunit , SCNEA , alpha-NaCH , epithelial Na(+) channel subunit alpha , epithelial sodium channel ENaC alpha subunit , nonvoltage-gated sodium channel 1 subunit alpha , alpha ENaC-2 , alpha-ENaC , amiloride-sensitive epithelial sodium channel alpha subunit , amiloride-sensitive sodium channel subunit alpha 2 , nasal epithelial sodium channel alpha subunit , alpha cENaC 431 , amiloride-sensitve epithelial sodium channel alpha subunit , sodium channel, nonvoltage-gated 1, delta , ENaC alpha , amiloride-sensitive epithelial sodium channel , sodium channel, nonvoltage-gated, type I, alpha polypeptide , sodium channel, nonvoltage-gated, type I, alpha

GENE ID SPECIES
396608 Sus scrofa
403650 Canis lupus familiaris
443488 Ovis aries
451776 Pan troglodytes
100222046 Taeniopygia guttata
100484947 Ailuropoda melanoleuca
100014763 Monodelphis domestica
100009488 Oryctolagus cuniculus
6337 Homo sapiens
282348 Bos taurus
396050 Gallus gallus
397811 Xenopus laevis
428184 Gallus gallus
20276 Mus musculus
25122 Rattus norvegicus
100135613 Cavia porcellus
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