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SPPL2B 抗体

(Signal Peptide Peptidase-Like 2B (SPPL2B))
This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
SPPL2B 抗体  (N-Term) SPPL2B 抗体  (N-Term) SPPL2B 抗体 (N-Term) (ABIN2782090)

SPPL2B 适用: 人, 大鼠, Cow, 小鼠, Pig, 马, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

SPPL2B 抗体  (AA 93-142) SPPL2B 抗体  (AA 93-142) SPPL2B 抗体 (AA 93-142) (ABIN6738138)

SPPL2B 适用: 人, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

SPPL2B 抗体  (AA 492-592) SPPL2B 抗体  (AA 492-592) SPPL2B 抗体 (AA 492-592) (ABIN7169627)

SPPL2B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated

SPPL2B 抗体 by 适用

Find SPPL2B 抗体 for a variety of species such as anti-Human SPPL2B, anti-Cow SPPL2B, anti-Mouse SPPL2B. The species listed below are among those available. Click on a link to go to the corresponding products.

SPPL2B 抗体 by 应用范围

Find SPPL2B 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

SPPL2B 抗体 by 抗体来源

Find SPPL2B 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SPPL2B 抗体 by 抗原表位

Find SPPL2B 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SPPL2B 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SPPL2B 抗体. Click on a link to go to the corresponding products.

SPPL2B 抗体 by 克隆

Find SPPL2B 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

SPPL2B 抗体 by 标记

Find SPPL2B 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SPPL2B 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
Application WB, IHC
Validations
  • (1)
  • (3)
Cat. No. ABIN2782090
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6738138
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7169627
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243975
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243976
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
Cat. No. ABIN1386177
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7169630
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7169629
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7169628
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA
Validations
Cat. No. ABIN7096696
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN6752476
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SPPL2B 抗体

Del Campo, Hoozemans, Dekkers, Rozemuller, Korth, Müller-Schiffmann, Scheltens, Blankenstein, Jimenez, Veerhuis, Teunissen: "BRI2-BRICHOS is increased in human amyloid plaques in early stages of Alzheimer's disease." in: Neurobiology of aging, Vol. 35, Issue 7, pp. 1596-604, (2014) (PubMed).

Friedmann, Lemberg, Weihofen, Dev, Dengler, Rovelli, Martoglio: "Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins." in: The Journal of biological chemistry, Vol. 279, Issue 49, pp. 50790-8, (2004) (PubMed).

Grigorenko, Moliaka, Korovaitseva, Rogaev: "Novel class of polytopic proteins with domains associated with putative protease activity." in: Biochemistry. Biokhimii?a, Vol. 67, Issue 7, pp. 826-35, (2002) (PubMed).

Weihofen, Binns, Lemberg, Ashman, Martoglio: "Identification of signal peptide peptidase, a presenilin-type aspartic protease." in: Science (New York, N.Y.), Vol. 296, Issue 5576, pp. 2215-8, (2002) (PubMed).

Nagase, Kikuno, Ishikawa, Hirosawa, Ohara: "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 2, pp. 143-50, (2000) (PubMed).

Aliases for SPPL2B 抗体

signal peptide peptidase-like 2 (sppl2) 抗体
signal peptide peptidase like 2B (sppl2b) 抗体
signal peptide peptidase like 2B S homeolog (sppl2b.S) 抗体
signal peptide peptidase like 2B (SPPL2B) 抗体
signal peptide peptidase like 2B (Sppl2b) 抗体
signal peptide peptidase-like 2B (Sppl2b) 抗体
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