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SETD7 抗体

(SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
SETD7 抗体  (AA 257-366) SETD7 抗体  (AA 257-366) SETD7 抗体 (AA 257-366) (ABIN566461)

SETD7 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 5B4 unconjugated

SETD7 抗体  (AA 107-366) SETD7 抗体  (AA 107-366) SETD7 抗体 (AA 107-366) (ABIN7193392)

SETD7 适用: 人, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 1B3B8 unconjugated

SETD7 抗体  (AA 107-366) SETD7 抗体  (AA 107-366) SETD7 抗体 (AA 107-366) (ABIN7193393)

SETD7 适用: 人, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 3D6G11 unconjugated

SETD7 抗体 by 适用

Find SETD7 抗体 for a variety of species such as anti-Human SETD7, anti-Mouse SETD7, anti-Rat SETD7. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find SETD7 抗体 validated for a specific application such as WB, ELISA, FACS, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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SETD7 抗体 by 抗原表位

Find SETD7 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SETD7 抗体 by 克隆形成能力

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SETD7 抗体 by 克隆

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SETD7 抗体 by 标记

Find SETD7 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

SETD7 抗体 by Fragment

Find SETD7 抗体 with a specific Fragment. The Fragment listed below are among those available. Click on a link to go to the corresponding products.

Popular SETD7 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (5)
Cat. No. ABIN566461
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey, Rat
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (5)
Cat. No. ABIN7193392
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Monkey, Rat
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (5)
Cat. No. ABIN7193393
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN566460
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
  • (3)
Cat. No. ABIN1500903
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN364315
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (2)
Cat. No. ABIN6147651
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN387997
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7155517
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN543332
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IF, ICC
Validations
  • (4)
  • (1)
Cat. No. ABIN532913
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6972701
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN6265019
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN321546
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1500902
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SETD7 抗体

Zhao, Zhao, Gu, Yin, Shen, Tang, Xia, Zhang, Zhao, Yang, Zhang: "Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial." in: Theranostics, Vol. 10, Issue 8, pp. 3533-3545, (2021) (PubMed).

Yin, Jia, Miron, Long, Xu, Wei, Wu, Zhang, Li: "Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds." in: Acta biomaterialia, Vol. 73, pp. 522-530, (2018) (PubMed).

Subramanian, Jia, Kapoor-Vazirani, Powell, Collins, Sharma, Peng, Cheng, Vertino: "Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase." in: Molecular cell, Vol. 30, Issue 3, pp. 336-47, (2008) (PubMed).

Hotz, Peters: "Protein demethylation required for DNA methylation." in: Nature genetics, Vol. 41, Issue 1, pp. 10-1, (2008) (PubMed).

Narayanan, Ruyechan, Kristie: "The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 26, pp. 10835-40, (2007) (PubMed).

Chuikov, Kurash, Wilson, Xiao, Justin, Ivanov, McKinney, Tempst, Prives, Gamblin, Barlev, Reinberg: "Regulation of p53 activity through lysine methylation." in: Nature, Vol. 432, Issue 7015, pp. 353-60, (2004) (PubMed).

Kwon, Chang, Kwak, Lee, Joachimiak, Kim, Lee, Cho: "Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet." in: The EMBO journal, Vol. 22, Issue 2, pp. 292-303, (2003) (PubMed).

Xiao, Jing, Wilson, Walker, Vasisht, Kelly, Howell, Taylor, Blackburn, Gamblin: "Structure and catalytic mechanism of the human histone methyltransferase SET7/9." in: Nature, Vol. 421, Issue 6923, pp. 652-6, (2003) (PubMed).

Wysocka, Myers, Laherty, Eisenman, Herr: "Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1." in: Genes & development, Vol. 17, Issue 7, pp. 896-911, (2003) (PubMed).

Aliases for SETD7 抗体

SET domain containing lysine methyltransferase 7 (SETD7) 抗体
SET domain containing (lysine methyltransferase) 7 (setd7) 抗体
SET domain containing (lysine methyltransferase) 7 (Setd7) 抗体
1600028F23Rik 抗体
H3K4MT 抗体
KMT7 抗体
mKIAA1717 抗体
SET7 抗体
set7 抗体
Set7 抗体
SET7/9 抗体
Set7/9 抗体
SET9 抗体
zgc:92330 抗体
zgc:101860 抗体
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