anti-Runt-Related Transcription Factor 2 (RUNX2) 抗体

RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. 再加上,我们可以发RUNX2 试剂盒 (47)RUNX2 蛋白 (12)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
RUNX2 12393 Q08775
RUNX2 860 Q13950
RUNX2 367218  

antibodies-online.cn销售最多的anti-RUNX2 抗体

Showing 10 out of 237 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:2500<br><b>Positive Control: </b>HepG2 cell lysate Sample Type: Lane 1:241 µg mouse mesenchymal stem cell lysate <br />Primary Antibody Dilution: 1:0000<br />Secondary Antibody: Anti-rabbit-HRP <br />Secondary Antibody Dilution: 1:00,000 Color/Signal Descriptions: RUNX2 <br /> Gene Name: Anonymous <br /><br />Submitted by: 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
Cow 非结合性 WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-RUNX2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control:.21_B cell lysate <br /> RUNX2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
Cow 非结合性 WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 5至7个工作日
¥16,831.21
详细
Cow 非结合性 WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 5至7个工作日
¥16,831.21
详细
Cow 非结合性 WB <b>WB Suggested Anti-Runx2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Rat Liver WB Suggested Anti-Runx2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Rat Liver 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
非结合性 WB Observed bind size: 62KD Anti-RUNX2 Picoband antibody,  All lanes: Anti RUNX2  at 0.5ug/ml WB: Recombinant Human RUNX2 Protein 0.5ng Predicted bind size: 50KD Observed bind size: 50KD 100 μg Log in to see 26至32个工作日
¥2,919.96
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非结合性 EIA 0.4 mL Log in to see 29至35个工作日
¥4,086.26
详细
小鸡 非结合性 IHC, WB Immunohistochemical analysis of RUNX2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of RUNX2 expression in Saos2 (A), HepG2 (B), Jurkat (C) whole cell lysates. 200 μL Log in to see 7至8个工作日
¥3,941.44
详细
非结合性 WB Anti-RUNX2 antibody, Western blotting Lane 1: Rat Thymus Tissue Lysate Lane 2: Rat Testis Tissue Lysate 100 μg Log in to see 26至32个工作日
¥2,560.58
详细
非结合性 WB Western blot analysis of RUNX2 expression in K562 (A), Hela (B) whole cell lysates. 200 μL Log in to see 7至8个工作日
¥3,981.76
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通过反应活性、应用领域、克隆类型和共轭标记 RUNX2 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-RUNX2 抗体

  1. Human Polyclonal RUNX2 Primary Antibody for DB - ABIN389942 : McNamara, Sjöström, Burgess, Kim, Liu, Gordonov, Moghe, Meek, Oreffo, Su, Dalby: Skeletal stem cell physiology on functionally distinct titania nanotopographies. in Biomaterials 2011 (PubMed)
    Show all 8 Pubmed References

  2. Human Polyclonal RUNX2 Primary Antibody for WB - ABIN3043708 : Li, Chen, Peng, Zhou, Fang: Pulsed electromagnetic fields protect the balance between adipogenesis and osteogenesis on steroid-induced osteonecrosis of femoral head at the pre-collapse stage in rats. in Bioelectromagnetics 2014 (PubMed)
    Show all 6 Pubmed References

  3. Human Polyclonal RUNX2 Primary Antibody for WB - ABIN3043428 : Wang, Mu, Fan, Yu, Yan, Lei, Tang, Wang, Zheng, Yu, Zhang: Insulin-like growth factor 1 can promote the osteogenic differentiation and osteogenesis of stem cells from apical papilla. in Stem cell research 2012 (PubMed)
    Show all 6 Pubmed References

  4. Human Polyclonal RUNX2 Primary Antibody for EMSA - ABIN3434043 : Huang, Xie, Konaka, Sodek, Zhau, Chung: Human osteocalcin and bone sialoprotein mediating osteomimicry of prostate cancer cells: role of cAMP-dependent protein kinase A signaling pathway. in Cancer research 2005 (PubMed)
    Show all 5 Pubmed References

  5. Human Monoclonal RUNX2 Primary Antibody for IF, IHC (p) - ABIN514045 : Wang, Li, Li, Yang, Sasaki, Wang, Zhou, Araki, Mezawa, Takai, Ogata: Effects of inorganic polyphosphate on bone sialoprotein gene expression. in Gene 2010 (PubMed)
    Show all 5 Pubmed References

  6. Human Polyclonal RUNX2 Primary Antibody for ICC, IF - ABIN4351437 : Mao, Shin, Mooney: Effects of substrate stiffness and cell-cell contact on mesenchymal stem cell differentiation. in Biomaterials 2016 (PubMed)
    Show all 4 Pubmed References

  7. Human Polyclonal RUNX2 Primary Antibody for ICC, IF - ABIN4351441 : Martínez-Abadías, Holmes, Pankratz, Wang, Zhou, Jabs, Richtsmeier: From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome. in Disease models & mechanisms 2013 (PubMed)
    Show all 3 Pubmed References

  8. Human Monoclonal RUNX2 Primary Antibody for IF, IHC (p) - ABIN560185 : Sase, Suzuki, Miura, Shiiba, Sato, Nakamura, Takagi, Onodera, Miki, Watanabe, Ishida, Ohnuma, Sasaki, Sato, Karasawa, Shibata, Unno, Sasaki, Sasano: Runt-related transcription factor 2 in human colon carcinoma: a potent prognostic factor associated with estrogen receptor. in International journal of cancer. Journal international du cancer 2012 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal RUNX2 Primary Antibody for ICC, IF - ABIN4351459 : Mao, Shin, Utech, Wang, Uzun, Li, Cooper, Hu, Zhang, Weitz, Mooney: Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery. in Nature materials 2016 (PubMed)
    Show all 2 Pubmed References

  10. Cow (Bovine) Polyclonal RUNX2 Primary Antibody for WB - ABIN2780588 : Lee, Lee, Ryoo, Park, Park, Bae, Cho, Park: The odontogenic ameloblast-associated protein (ODAM) cooperates with RUNX2 and modulates enamel mineralization via regulation of MMP-20. in Journal of cellular biochemistry 2010 (PubMed)
    Show all 2 Pubmed References

更多抗RUNX2的相互作用对抗体

Zebrafish Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Runx2 may have an evolutionarily conserved role in axis formation

Mouse (Murine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. These results suggest that Dietary methionine restriction (MR) alters bone remodeling and apposition. In MR mice, miR (显示 MLXIP 抗体)-31 in plasma and liver, and miR (显示 MLXIP 抗体)-133a, miR (显示 MLXIP 抗体)-335-5p, and miR (显示 MLXIP 抗体)-204 in the bone marrow was elevated. These miRNAs were shown previously to target and regulate Osterix (显示 SP7 抗体) and RUNX2 in bone, which could inhibit osteoblast differentiation and function.

  2. SIRT1 (显示 SIRT1 抗体) interacts with and promotes the transactivation potential of RUNX2.

  3. ABL (显示 ABL1 抗体) potentiated the assembly and activation of the RUNX2-TAZ (显示 TAZ 抗体) master transcription factor complex that is required for osteoblastogenesis, while antagonizing PPARgamma (显示 PPARG 抗体)-mediated adipogenesis.

  4. urther investigation indicated that p205 (显示 GNB2L1 抗体) may disturb the formation of Runx2/Ids (显示 IDS 抗体) complex and free more Runx2 to induce the differentiation process. Taken together, our findings demonstrated for the first time that p205 (显示 GNB2L1 抗体) functions as an activator in osteoblast differentiation.

  5. identified a novel genomic region in which DNA methylation (显示 HELLS 抗体) status is related to Runx2 expression and detected demethylation of Runx2-DMR (显示 WDR20 抗体) during osteoblastic differentiation in mouse and dog.

  6. overexpression of Fam3c (显示 FAM3C 抗体) caused reduction of Runx2 expression at both mRNA and protein levels. Fam3c (显示 FAM3C 抗体) was localized in the cytoplasm and it was not secreted outside the cell during osteoblast differentiation and therefore, may function intracellularly. Furthermore, Fam3c (显示 FAM3C 抗体) and TGF-beta1 (显示 TGFB1 抗体) were found to regulate each other reciprocally

  7. MAP kinase (显示 MAPK1 抗体)-dependent RUNX2 phosphorylation Is necessary for epigenetic modification of chromatin during osteoblast differentiation.

  8. These results suggested that endogenous PTH enhanced BMPR2 expression by a cAMP/PKA/CREB pathway in osteoblasts, and increased RUNX2 expression through transduction of the BMP/pSMAD1/5/8 signaling pathway

  9. suggest that RUNX2 and USAG-1 (显示 SOSTDC1 抗体) act in an antagonistic manner

  10. results provide evidence that WWP2 (显示 WWP2 抗体) serves as a positive regulator of osteogenesis by augmenting RUNX2 transactivation in a non-proteolytic mono-ubiquitination manner.

Human Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. TP(thymidine phosphorylase (显示 TYMP 抗体) ) curbed the expression of three proteins-IRF8 (显示 IRF8 抗体), RUNX2, and osterix (显示 SP7 抗体). This downregulation was epigenetically driven: High levels of 2DDR, a product of TP secreted by myeloma cells, activated PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体) signaling and increased the methyltransferase DNMT3A's expression

  2. Overexpression of miR (显示 MLXIP 抗体)-196b suppressed cell viability, migration, invasion, and induced apoptosis as well as inhibited TGF-beta (显示 TGFB1 抗体) induced epithelial mesenchymal transition process in A549 cells. In addition, Runx2 was a putative target of miR (显示 MLXIP 抗体)-196b, and Runx2 silence remarkably increased cell apoptosis and abolished the promotive effects of miR (显示 MLXIP 抗体)-196b suppression on cell viability, migration and invasion.

  3. This study showed that si-Grem2 (显示 GREM2 抗体) increased the BMP-2 (显示 BMP2 抗体)-induced osteogenic differentiation of hBMSCs via the BMP-2 (显示 BMP2 抗体)/Smad (显示 SMAD1 抗体)/Runx2 pathway.

  4. Runx2 promotes autophagy in metastatic breast cancer cells by increasing acetylation of alpha-tubulin (显示 TUBA4A 抗体) sub-units of microtubules.

  5. Mutation in the RUNX2 gene is associated with acute myeloid leukemia (显示 BCL11A 抗体) patients with lympho-myeloid clonal hematopoiesis.

  6. present observations strongly suggest that RUNX2/mutant p53 (显示 TP53 抗体)/TAp63-regulatory axis is one of the key determinants of SAHA sensitivity of p53 (显示 TP53 抗体)-mutated pancreatic cancer cells

  7. All the three novel RUNX2 mutations significantly reduced the transactivation activity of RUNX2 on osteocalcin (显示 BGLAP 抗体) promoter.

  8. miR (显示 MLXIP 抗体)-466-mediated attenuation of RUNX2 as a novel therapeutic approach to regulate prostate cancer growth, particularly metastasis to bone.

  9. miR (显示 MLXIP 抗体)-203 has a crucial role in suppressing heterotopic ossification by directly targeting Runx2.

  10. mechanical load upregulates expression of Runx2 gene via potentiation of PC1 (显示 PCSK1 抗体)-JAK2 (显示 JAK2 抗体)/STAT3 (显示 STAT3 抗体) signaling axis, culminating to possibly control osteoblastic differentiation and ultimately bone formation.

Rabbit Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. The results suggest that gene therapy using Runx2-modi fi ed dental pulp stem cells was more effective during bone deposition and new bone formation in tibia Distraction osteogenesis.

  2. Runx2-modified adipose-derived stem cells promote tendon graft integration in anterior cruciate ligament reconstruction.

  3. The OPG (显示 TNFSF11 抗体) expression levels decreased while those of RANKL (显示 TNFSF11 抗体) and RUNX2 increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

Xenopus laevis Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. These data also indicate that MGP (显示 MGP 抗体) is under dual regulation by runx2 through the use of various isoforms and context-dependent formation of transcriptional complexes.

Pig (Porcine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Klotho (显示 KL 抗体) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (显示 GRK4 抗体)-RUNX2 pathway.

RUNX2 抗原简介

蛋白简介

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Gene names and symbols associated with RUNX2

  • runt-related transcription factor 2a (runx2a) 抗体
  • transcription factor Cbfa1 (runx2) 抗体
  • runt-related transcription factor 2 (RUNX2) 抗体
  • runt-related transcription factor 2 (runx2) 抗体
  • runt related transcription factor 2 (Runx2) 抗体
  • runt-related transcription factor 2 (Runx2) 抗体
  • runt-related transcription factor 2 (LOC100339156) 抗体
  • runt-related transcription factor 2-like (LOC100737965) 抗体
  • AML3 抗体
  • Cbf 抗体
  • CBF-alpha-1 抗体
  • Cbfa-1 抗体
  • CBFA1 抗体
  • CCD 抗体
  • CCD1 抗体
  • CLCD 抗体
  • LS3 抗体
  • OSF-2 抗体
  • OSF2 抗体
  • PEA2aA 抗体
  • Pebp2a1 抗体
  • pebp2a2 抗体
  • PEBP2aA 抗体
  • pebp2aa1 抗体
  • Pebpa2a 抗体
  • RUNX2 抗体

Protein level used designations for RUNX2

runt-related transcription factor 2 , transcription factor Runx2a , transcription factor Cbfa1 , runt-related transcription factor 2-like , AKV core binding factor , CBF-alpha-1 , PEA2-alpha A , PEBP2 alpha A , SL3-3 enhancer factor 1 alpha A subunit , acute myeloid leukemia 3 protein , core binding factor alpha 1 , osteoblast-specific transcription factor 2 , polyomavirus enhancer-binding protein 2 alpha A subunit , runt domain, alpha subunit 1 , PEBP2-alpha A , SL3/AKV core-binding factor alpha A subunit , core-binding factor, runt domain, alpha subunit 1 , oncogene AML-3 , runt-related factor 2 , core-binding factor subunit alpha-1 , runt related transcription factor 2 , Runx2 spliced isoform , runt-related transcription factor 2 type I , runt-related transcription factor 2 type II , core binding factor alpha 1 subunit

GENE ID SPECIES
405784 Danio rerio
445986 Takifugu rubripes
449531 Canis lupus familiaris
472017 Pan troglodytes
703331 Macaca mulatta
100080409 Ornithorhynchus anatinus
100189546 Xenopus (Silurana) tropicalis
100222668 Taeniopygia guttata
100406564 Callithrix jacchus
100453201 Pongo abelii
100549663 Meleagris gallopavo
100555776 Anolis carolinensis
100619969 Monodelphis domestica
12393 Mus musculus
860 Homo sapiens
474923 Canis lupus familiaris
536911 Bos taurus
100008943 Oryctolagus cuniculus
367218 Rattus norvegicus
100037059 Xenopus laevis
373919 Gallus gallus
100734175 Cavia porcellus
100033890 Equus caballus
100155806 Sus scrofa
100339156 Oryctolagus cuniculus
100861217 Capra hircus
101115489 Ovis aries
100737965 Sus scrofa
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