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anti-Runt-Related Transcription Factor 1 (RUNX1) 抗体

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. 再加上,我们可以发RUNX1 试剂盒 (14)RUNX1 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
RUNX1 12394 Q03347
RUNX1 861 Q01196
RUNX1 50662 Q63046

antibodies-online.cn销售最多的anti-RUNX1 抗体

Showing 10 out of 272 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB Sample Type : Mouse, post-natal day (p) 0 retinal ganglion cells Primary Antibody Dilution : 1:1500 Secondary Antibody : Donkey anti rabbit IgG Alexa 594 Secondary Antibody Dilution : 1:1000 Gene Name : RUNX1  Submitted by : Anonymous WB Suggested Anti-RUNX1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: PANC1 cell lysate There is BioGPS gene expression data showing that RUNX1 is expressed in PANC1 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
Cow 非结合性 WB WB Suggested Anti-RUNX1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Jurkat cell lysate WB Suggested Anti-RUNX1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:12500  Positive Control: Jurkat cell lysate  RUNX1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
Cow 非结合性 WB WB Suggested Anti-RUNX1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate WB Suggested Anti-RUNX1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Jurkat cell lysate  RUNX1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
Cow 非结合性 WB WB Suggested Anti-RUNX1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:7812500Positive Control: Human Small Intestine 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
Cow 非结合性 IHC, WB WB Suggested Anti-RUNX1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: SH-SYSY cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
Cow 非结合性 WB WB Suggested Anti-RUNX1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 FACS, IF, IHC (p), WB Western blot analysis of RUNX1-S276 (ABIN650732) in K562 cell line lysates (35 µg/lane). RUNX1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with RUNX1 Antibody (S276) (ABIN650732), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 5至8个工作日
¥2,606.76
详细
非结合性 ELISA, WB Western blot analysis of extracts from HepG2 cells treated with PMA 125ng/ml 30', using AML1 (Phospho-Ser435) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
非结合性 EIA, WB Western blot analysis of RUNX1 in Raji cell lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 29至35个工作日
¥3,632.23
详细
非结合性 ELISA, WB Western blot analysis of extracts from HepG2 cells, treated with PMA 125ng/ml 30', using AML1 (Ab-435) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细

通过反应活性、应用领域、克隆类型和共轭标记 RUNX1 抗体

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引用最多的anti-RUNX1 抗体

  1. Human Polyclonal RUNX1 Primary Antibody for EIA, WB - ABIN500646 : Lee, Jenner, Boyer, Guenther, Levine, Kumar, Chevalier, Johnstone, Cole, Isono, Koseki, Fuchikami, Abe, Murray, Zucker, Yuan, Bell, Herbolsheimer, Hannett, Sun, Odom, Otte, Volkert, Bartel, Melton, Gifford, Jaenisch, Young: Control of developmental regulators by Polycomb in human embryonic stem cells. in Cell 2006 (PubMed)
    Show all 4 references for ABIN500646

  2. Human Polyclonal RUNX1 Primary Antibody for FACS, IF - ABIN650732 : Moosavi, Sanchez, Adeyinka: Marker chromosomes are a significant mechanism of high-level RUNX1 gene amplification in hematologic malignancies. in Cancer genetics and cytogenetics 2009 (PubMed)
    Show all 2 references for ABIN650732

  3. Human Polyclonal RUNX1 Primary Antibody for ELISA, WB - ABIN1532121 : Nucifora, Birn, Espinosa, Erickson, LeBeau, Roulston, McKeithan, Drabkin, Rowley: Involvement of the AML1 gene in the t(3,21) in therapy-related leukemia and in chronic myeloid leukemia in blast crisis. in Blood 1993 (PubMed)

  4. Cow (Bovine) Polyclonal RUNX1 Primary Antibody for WB - ABIN2792628 : Takeshita, Ichikawa, Nitta, Goyama, Asai, Ogawa, Chiba, Kurokawa: AML1-Evi-1 specifically transforms hematopoietic stem cells through fusion of the entire Evi-1 sequence to AML1. in Leukemia 2008 (PubMed)

  5. Cow (Bovine) Polyclonal RUNX1 Primary Antibody for WB - ABIN2780380 : Ghozi, Bernstein, Negreanu, Levanon, Groner: Expression of the human acute myeloid leukemia gene AML1 is regulated by two promoter regions. in Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)

更多抗RUNX1的相互作用对抗体

Mouse (Murine) Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. Knock-down of PLC-gamma-1 (显示 PLCG1 抗体) induced foreign body giant cell formation.PLC-gamma-1-deficiency caused a decrease in RUNX1 and subsequent PU.1 upregulation while subsequent rescue of RUNX1 in sh-PLC-gamma-1 (显示 PLCG1 抗体)-transfected cells strongly inhibited foreign body giant cell formation.

  2. this study shows that distinct, asynchronous and stage-specific transcription factors (TCF-1 (显示 HNF1A 抗体), GATA-3 (显示 GATA3 抗体) and Runx1) activate Bcl11b (显示 BCL11B 抗体) for T cell commitment

  3. Inhibition of Runx1 in multipotential myeloid precursor cells is important for osteoclast formation and function.

  4. Silencing of Runx1 attenuated the LPS (显示 TLR4 抗体)-induced IL-1beta (显示 IL1B 抗体) and IL-6 (显示 IL6 抗体) production levels, but the TNF-alpha (显示 TNF 抗体) levels were not affected. Overexpression of RUNX1 promoted IL-1beta (显示 IL1B 抗体) and IL-6 (显示 IL6 抗体) production in response to LPS (显示 TLR4 抗体) stimulation.

  5. the Acute Myeloid Leukemia-1a (AML-1a) transcription factor, a regulator of immune gene expression, was identified as potentially sensitive to nucleosomal regulation within the Ly49 gene family. This result was confirmed in RMA, a cell line with natural expression of Ly49, using MNase-Seq to generate a nucleosome map of chromosome 6, where the Ly49 gene family is located

  6. Data show that immature Runx1-deficient CD4 (显示 CD4 抗体)(+) T cells are eliminated in the periphery by the activation and fixation of the classical complement pathway.

  7. Runx1 deficiency enhanced CGRP expression and disrupted BMP4-induced neurite outgrowth inhibition in DRG.

  8. Runx1 could be manipulated after injury to promote neuronal differentiation to facilitate repair of the CNS.

  9. Runx1 haploinsufficiency appears to predispose FPD patients to MM by expanding the pool of stem/progenitor cells and blocking myeloid differentiation in response to G-CSF (显示 CSF3 抗体).

  10. Runx1 has an important role in Nf1 (显示 NF1 抗体) neurofibroma initiation

Human Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. RUNX1 and AXIN1 (显示 AXIN1 抗体) proteins are strongly correlated in ER(-) tumors as well.

  2. he data suggest a central role for RUNX1 as master regulator of gene expression in the U87 glioblastoma multiforme cell line and mark RUNX1 as a potential target for novel future therapies for glioblastoma multiforme

  3. Study highlights the importance of interactions among lncRNA HCP5, microRNA-139, and transcription factor RUNX1 in regulating the malignant behavior of glioma cells. HCP5 down-regulated miR-139 to up-regulate RUNX1. RUNX1 promoted AEG-1 expression, which was involved in a series of oncogenic effects in glioma cells. RUNX1 also up-regulated HCP5 expression, which formed a positive feedback loop.

  4. Data suggest that RUNX1 functions in stem cells regulating cell differentiation; cancer cells appear to have corrupted this function of RUNX1 into promotion of oncogenesis. [REVIEW]

  5. the AML1-ETO (显示 RUNX1T1 抗体) fusion protein increases the expression of SIRT1 (显示 SIRT1 抗体), possibly by binding to the promoter region of SIRT1 (显示 SIRT1 抗体) to activate its transcription in t(8;21) AML.

  6. the Notch (显示 NOTCH1 抗体) pathway DNA-binding protein (显示 UBE2V1 抗体) RBP-J (显示 RBPJ 抗体) is the key cellular factor hijacked by EBNA2 to direct activation of RUNX1 transcription via upstream super-enhancers.

  7. revealed more than 170 NFAT (显示 NFATC1 抗体)-associated proteins, half of which are involved in transcriptional regulation. Among them are many hitherto unknown interaction partners of NFATc1 (显示 NFATC1 抗体) and NFATc2 (显示 NFAT1 抗体) in T cells, such as Raptor (显示 RPTOR 抗体), CHEK1 (显示 CHEK1 抗体), CREB1 (显示 CREB1 抗体), RUNX1, SATB1 (显示 SATB1 抗体), Ikaros (显示 IKZF1 抗体), and Helios (显示 ZNFN1A2 抗体).

  8. Data show that the interaction between aptamer and AML1 (RUNX1) protein DNA-binding domain known as the Runt domain (RD) is driven by a large enthalpy change.

  9. A feedback circuitry involving miR (显示 MLXIP 抗体)-9-1 and RUNX1-RUNX1T1 (显示 RUNX1T1 抗体).

  10. The requirement for Runx1 in the normal hematopoietic development and its dysregulation through chromosomal translocations and loss-of-function mutations as found in acute myeloid leukemias highlight the importance of this transcription factor in the healthy blood system.

Zebrafish Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. Our data suggest that runx1 and cbfb are required at 2 different steps during early hematopoietic stem cell development

  2. We propose that cohesin and CTCF (显示 CTCF 抗体) have distinct functions in the regulation of runx1 during zebrafish embryogenesis.

  3. Morpholino knockdown of Myef2 (显示 MYEF2 抗体) or Runx1 in zebrafish results in reduced numbers of hematopoietic stem cells, suggesting that these two factors also interact in vivo to regulate hematopoiesis.

  4. Runx1 is induced by high Pu.1 level and in turn transrepresses pu.1 expression, thus constituting a negative feedback loop that fashions a favorable Pu.1 level required for balanced fate commitment to neutrophils versus macrophages.

  5. hematopoietic stem cell numbers depended on activity of the transcription factor Runx1, on blood flow, and on proper development of the dorsal aorta

  6. in zebrafish adult HSCs can be formed without an intact runx1.

  7. Zebrafish embryos lacking Rad21 (显示 RAD21 抗体), or cohesin subunit Smc3 (显示 SMC3 抗体), fail to express runx3 (显示 RUNX3 抗体) and lose hematopoietic runx1 expression in early embryonic development.

Xenopus laevis Runt-Related Transcription Factor 1 (RUNX1) interaction partners

  1. Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus.

  2. ETV6-RUNX1 (TEL-AML1) fusion and hyperdiploidy (>50 chromosomes) are favorable genetic features in childhood acute lymphoblastic leukemia (ALL).

  3. reveal a shift in Runx2 (显示 RUNX2 抗体) function protein during vertebrate evolution towards its exclusive roles in cartilage hypertrophy and bone differentiation within the amniote lineage

RUNX1 抗原简介

蛋白简介

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RUNX1

  • runt-related transcription factor 1 (RUNX1) 抗体
  • runt-related transcription factor (runt) 抗体
  • runt related transcription factor 1 (Runx1) 抗体
  • runt-related transcription factor 1 (runx1) 抗体
  • runt-related transcription factor 1 (Runx1) 抗体
  • AI462102 抗体
  • aml 抗体
  • aml-1 抗体
  • Aml1 抗体
  • aml1-evi-1 抗体
  • amlcr1 抗体
  • cbfa2 抗体
  • evi-1 抗体
  • Pebp2a2 抗体
  • pebp2ab 抗体
  • Pebpa2b 抗体
  • Runx-1 抗体
  • runx1 抗体
  • runxa 抗体
  • XAML 抗体
  • Xaml1 抗体

Protein level used designations for RUNX1

runt-related transcription factor 1 , runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) , runt-related transcription factor , runt protein , CBF-alpha-2 , PEA2-alpha B , PEBP2-alpha B , SL3-3 enhancer factor 1 alpha B subunit , SL3/AKV core-binding factor alpha B subunit , acute myeloid leukemia 1 protein , core binding factor alpha 2 , core-binding factor subunit alpha-2 , oncogene AML-1 , polyomavirus enhancer-binding protein 2 alpha B subunit , runt domain, alpha subunit 2 , AML1-EVI-1 fusion protein , core-binding factor, runt domain, alpha subunit 2 , aml1 , runt-related transcription factor a , runx1a , Acute myeloid leukemia 1 protein , Core-binding factor subunit alpha-2 , aml1 oncogene , ch-runtB2 , acute myeloid leukemia 1 , factor, runt domain, alpha subunit 2 , core-binding factor runt domain alpha subunit 2 (acute myeloid leukemia 1 oncogene) , runt related transcription factor 1

GENE ID SPECIES
473981 Pan troglodytes
100302713 Saccoglossus kowalevskii
12394 Mus musculus
861 Homo sapiens
58126 Danio rerio
379657 Xenopus laevis
396152 Gallus gallus
487746 Canis lupus familiaris
529631 Bos taurus
50662 Rattus norvegicus
100512633 Sus scrofa
100724149 Cavia porcellus
anti-RUNX1 (RUNX1) 抗体 精选生产商
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