anti-Runt-Related Transcription Factor 2 (RUNX2) 抗体

RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. 再加上,我们可以发RUNX2 试剂盒 (52)RUNX2 蛋白 (12)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
RUNX2 860 Q13950
RUNX2 12393 Q08775
RUNX2 367218  
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antibodies-online.cn销售最多的anti-RUNX2 抗体

Showing 10 out of 239 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:2500<br><b>Positive Control: </b>HepG2 cell lysate Sample Type: Lane 1:241 µg mouse mesenchymal stem cell lysate <br />Primary Antibody Dilution: 1:0000<br />Secondary Antibody: Anti-rabbit-HRP <br />Secondary Antibody Dilution: 1:00,000 Color/Signal Descriptions: RUNX2 <br /> Gene Name: Anonymous <br /><br />Submitted by: 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-RUNX2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control:.21_B cell lysate <br /> RUNX2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 2至3个工作日
$229.00
详细
Cow 非结合性 WB <b>WB Suggested Anti-RUNX2 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2至3个工作日
$229.00
详细
Cow 非结合性 WB <b>WB Suggested Anti-Runx2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Rat Liver WB Suggested Anti-Runx2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Rat Liver 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 WB Observed bind size: 62KD Anti-RUNX2 Picoband antibody,  All lanes: Anti RUNX2  at 0.5ug/ml WB: Recombinant Human RUNX2 Protein 0.5ng Predicted bind size: 50KD Observed bind size: 50KD 100 μg Log in to see 4至6个工作日
$240.00
详细
非结合性 FACS, IHC (p), WB Western blot analysis of anti-RUNX2 Antibody (S533) (ABIN392133) in HepG2 cell line lysates (35 µg/lane). RUNX2 (arrow) was detected using the purified polyclonal antibody. RUNX2 Antibody (S533) (ABIN392133) western blot analysis in Hob cell line lysates.This demonstrates the RUNX2 antibody detected the RUNX2 protein (arrow)(Kindly provided by Dr. John Wu). 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 DB Dot blot analysis of anti-Phospho-RUNX2-S533 Antibody (ABIN389942) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 EIA 0.4 mL Log in to see 6至8个工作日
$390.50
详细
小鸡 非结合性 IHC, WB Immunohistochemical analysis of RUNX2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of RUNX2 expression in Saos2 (A), HepG2 (B), Jurkat (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细

通过反应活性、应用领域、克隆类型和共轭标记 RUNX2 抗体

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引用最多的anti-RUNX2 抗体

  1. Human Polyclonal RUNX2 Primary Antibody for DB - ABIN389942 : McNamara, Sjöström, Burgess, Kim, Liu, Gordonov, Moghe, Meek, Oreffo, Su, Dalby: Skeletal stem cell physiology on functionally distinct titania nanotopographies. in Biomaterials 2011 (PubMed)
    Show all 8 Pubmed References

  2. Human Polyclonal RUNX2 Primary Antibody for WB - ABIN3043428 : Li, Chen, Peng, Zhou, Fang: Pulsed electromagnetic fields protect the balance between adipogenesis and osteogenesis on steroid-induced osteonecrosis of femoral head at the pre-collapse stage in rats. in Bioelectromagnetics 2014 (PubMed)
    Show all 6 Pubmed References

  3. Human Polyclonal RUNX2 Primary Antibody for WB - ABIN3043708 : Wang, Mu, Fan, Yu, Yan, Lei, Tang, Wang, Zheng, Yu, Zhang: Insulin-like growth factor 1 can promote the osteogenic differentiation and osteogenesis of stem cells from apical papilla. in Stem cell research 2012 (PubMed)
    Show all 6 Pubmed References

  4. Human Monoclonal RUNX2 Primary Antibody for IF, IHC (p) - ABIN514045 : Wang, Li, Li, Yang, Sasaki, Wang, Zhou, Araki, Mezawa, Takai, Ogata: Effects of inorganic polyphosphate on bone sialoprotein gene expression. in Gene 2010 (PubMed)
    Show all 5 Pubmed References

  5. Human Polyclonal RUNX2 Primary Antibody for EMSA - ABIN3434043 : Huang, Xie, Konaka, Sodek, Zhau, Chung: Human osteocalcin and bone sialoprotein mediating osteomimicry of prostate cancer cells: role of cAMP-dependent protein kinase A signaling pathway. in Cancer research 2005 (PubMed)
    Show all 5 Pubmed References

  6. Human Polyclonal RUNX2 Primary Antibody for ICC, IF - ABIN4351437 : Mao, Shin, Mooney: Effects of substrate stiffness and cell-cell contact on mesenchymal stem cell differentiation. in Biomaterials 2016 (PubMed)
    Show all 4 Pubmed References

  7. Human Polyclonal RUNX2 Primary Antibody for ICC, IF - ABIN4351441 : Martínez-Abadías, Holmes, Pankratz, Wang, Zhou, Jabs, Richtsmeier: From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome. in Disease models & mechanisms 2013 (PubMed)
    Show all 3 Pubmed References

  8. Human Monoclonal RUNX2 Primary Antibody for IF, IHC (p) - ABIN560185 : Sase, Suzuki, Miura, Shiiba, Sato, Nakamura, Takagi, Onodera, Miki, Watanabe, Ishida, Ohnuma, Sasaki, Sato, Karasawa, Shibata, Unno, Sasaki, Sasano: Runt-related transcription factor 2 in human colon carcinoma: a potent prognostic factor associated with estrogen receptor. in International journal of cancer. Journal international du cancer 2012 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal RUNX2 Primary Antibody for ICC, IF - ABIN4351459 : Mao, Shin, Utech, Wang, Uzun, Li, Cooper, Hu, Zhang, Weitz, Mooney: Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery. in Nature materials 2016 (PubMed)
    Show all 2 Pubmed References

  10. Cow (Bovine) Polyclonal RUNX2 Primary Antibody for WB - ABIN2780588 : Lee, Lee, Ryoo, Park, Park, Bae, Cho, Park: The odontogenic ameloblast-associated protein (ODAM) cooperates with RUNX2 and modulates enamel mineralization via regulation of MMP-20. in Journal of cellular biochemistry 2010 (PubMed)
    Show all 2 Pubmed References

更多抗RUNX2的相互作用对抗体

Human Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Osterix (显示 SP7 抗体) and RUNX2 are transcriptional regulators of sclerostin (显示 SOST 抗体) in human bone

  2. High RUNX2 expression is associated with invasive and metastatic potentials of gastric cancer.

  3. These findings suggest possible involvement of RUNX2-rs194328 in the etiology of NS-CL+/-P in Korean cleft-parent trios without excess parental transmission.

  4. WWOX (显示 WWOX 抗体) expression was strongly inhibited in human lung cancers and lung cancer cell lines. Reintroducing WWOX (显示 WWOX 抗体) into lung cancer cells inhibited their invasive phenotype through downregulating RUNX2 and its target genes including MMP-9 (显示 MMP9 抗体) expression.

  5. our results strongly suggest that RUNX2 might be a key player in receptor tyrosine kinase (显示 RET 抗体) (RTK)-based autocrine loops and a mediator of resistance to BRAF (显示 BRAF 抗体) V600E inhibitors involving RTK up regulation in melanoma.

  6. Thus, WNT (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) activation is required for RUNX2 expression in at least some osteosarcoma cell types, where RUNX2 is known to promote expression of metastasis related genes.

  7. miR (显示 MLXIP 抗体)-105/Runx2 axis mediates FGF2 (显示 FGF2 抗体)-induced ADAMTS (显示 ADAMTS13 抗体) expression in osteoarthritis cartilage.

  8. regulation of gal-3 (显示 LGALS3 抗体) expression was strongly correlated with runx2 transcription factor in human thyroid carcinoma.

  9. Studied association of runt-related transcription factor 2 (RUNX2) polymorphisms with susceptibility and prognosis of ossification of posterior longitudinal ligament.

  10. these studies define a novel fibrinogen-alpha9beta1-SMAD1 (显示 GARS 抗体)/5/8-RUNX2 signaling axis can efficiently induce osteogenic differentiation from human embryonic stem cells and induced pluripotent stem cells.

Zebrafish Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Runx2 may have an evolutionarily conserved role in axis formation

Mouse (Murine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. These data suggest that NaF (显示 IL8 抗体) promotes the osteoblastic differentiation of MC3T3-E1 cells through the Runx2/Osterix (显示 SP7 抗体) pathway and may be effective for the treatment of bone-related disorders.

  2. results suggest that Edil3 may stimulate osteoblast differentiation and matrix mineralization by increasing expression of Runx2 through alpha5beta1 integrin /ERK (显示 EPHB2 抗体) pathway

  3. Taken together, these results demonstrate that piperine enhance osteoblast differentiation through AMPK (显示 PRKAA1 抗体) phosphorylation in MC3T3-E1 cells.

  4. Sphingosine 1 phosphate also up-regulated runt-related transcription factor 2 (Runx2) expression through S1PR2 (显示 S1PR2 抗体)/RhoA (显示 RHOA 抗体)/ROCK/Smad1 (显示 SMAD1 抗体)/5/8 signaling.

  5. Nearly half of all DNase (显示 DNASE2 抗体) hypersensitivity sites (both constitutive and dynamic) overlap binding events of the bone-essential RUNX2 and/or the chromatin-related CTCF (显示 CTCF 抗体) transcription factors.

  6. The findings suggest that the absence of uPA (显示 PLAU 抗体) correlates with increased levels of Runx transcriptional regulators in a way that promotes inflammation-associated carcinogenesis.

  7. Fam50a (显示 FAM50A 抗体) might be a new positive regulator of ameloblast differentiation, increasing binding affinity of Runx2 to Ambn (显示 AMBN 抗体) promoter by physically interacting with Runx2.

  8. Knockdown of MACF1 (显示 MACF1 抗体) in osteoblastic cells inhibits osteoblast differentiation through suppressing the beta-catenin (显示 CTNNB1 抗体)/TCF1 (显示 HNF1A 抗体)-Runx2 axis.

  9. These results suggest that Dietary methionine restriction (MR) alters bone remodeling and apposition. In MR mice, miR (显示 MLXIP 抗体)-31 in plasma and liver, and miR (显示 MLXIP 抗体)-133a, miR (显示 MLXIP 抗体)-335-5p, and miR (显示 MLXIP 抗体)-204 in the bone marrow was elevated. These miRNAs were shown previously to target and regulate Osterix (显示 SP7 抗体) and RUNX2 in bone, which could inhibit osteoblast differentiation and function.

  10. SIRT1 (显示 SIRT1 抗体) interacts with and promotes the transactivation potential of RUNX2.

Rabbit Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. The results suggest that gene therapy using Runx2-modi fi ed dental pulp stem cells was more effective during bone deposition and new bone formation in tibia Distraction osteogenesis.

  2. Runx2-modified adipose-derived stem cells promote tendon graft integration in anterior cruciate ligament reconstruction.

  3. The OPG (显示 TNFSF11 抗体) expression levels decreased while those of RANKL (显示 TNFSF11 抗体) and RUNX2 increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

Xenopus laevis Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. These data also indicate that MGP (显示 MGP 抗体) is under dual regulation by runx2 through the use of various isoforms and context-dependent formation of transcriptional complexes.

Pig (Porcine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Klotho (显示 KL 抗体) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (显示 GRK4 抗体)-RUNX2 pathway.

RUNX2 抗原简介

蛋白简介

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Gene names and symbols associated with RUNX2

  • runt related transcription factor 2 (RUNX2) 抗体
  • runt-related transcription factor 2a (runx2a) 抗体
  • runt related transcription factor 2 (Runx2) 抗体
  • runt-related transcription factor 2 (Runx2) 抗体
  • runt related transcription factor 2 (runx2) 抗体
  • uncharacterized LOC449531 (LOC449531) 抗体
  • runt-related transcription factor 2 (LOC703331) 抗体
  • runt-related transcription factor 2 (LOC100549663) 抗体
  • runt related transcription factor 2 L homeolog (runx2.L) 抗体
  • runt-related transcription factor 2 (RUNX2) 抗体
  • aml3 抗体
  • Cbf 抗体
  • CBF-alpha-1 抗体
  • Cbfa-1 抗体
  • cbfa1 抗体
  • ccd 抗体
  • ccd1 抗体
  • CLCD 抗体
  • LS3 抗体
  • OSF-2 抗体
  • osf2 抗体
  • pea2aa 抗体
  • pebp2a1 抗体
  • pebp2a2 抗体
  • pebp2aa 抗体
  • pebp2aa1 抗体
  • Pebpa2a 抗体
  • RUNX2 抗体

Protein level used designations for RUNX2

PEA2-alpha A , PEBP2-alpha A , SL3-3 enhancer factor 1 alpha A subunit , SL3/AKV core-binding factor alpha A subunit , acute myeloid leukemia 3 protein , core-binding factor, runt domain, alpha subunit 1 , oncogene AML-3 , osteoblast-specific transcription factor 2 , polyomavirus enhancer-binding protein 2 alpha A subunit , runt-related transcription factor 2 , transcription factor Runx2a , AKV core binding factor , CBF-alpha-1 , PEBP2 alpha A , core binding factor alpha 1 , runt domain, alpha subunit 1 , core-binding factor subunit alpha-1 , runt related transcription factor 2 , transcription factor Cbfa1 , runt-related factor 2 , core binding factor alpha 1 subunit , runt-related transcription factor 2-like , Runx2 spliced isoform , runt-related transcription factor 2 type I , runt-related transcription factor 2 type II

GENE ID SPECIES
860 Homo sapiens
405784 Danio rerio
12393 Mus musculus
367218 Rattus norvegicus
373919 Gallus gallus
445986 Takifugu rubripes
449531 Canis lupus familiaris
472017 Pan troglodytes
703331 Macaca mulatta
100008943 Oryctolagus cuniculus
100033890 Equus caballus
100080409 Ornithorhynchus anatinus
100189546 Xenopus (Silurana) tropicalis
100222668 Taeniopygia guttata
100406564 Callithrix jacchus
100453201 Pongo abelii
100549663 Meleagris gallopavo
100555776 Anolis carolinensis
100619969 Monodelphis domestica
100037059 Xenopus laevis
536911 Bos taurus
100737965 Sus scrofa
474923 Canis lupus familiaris
100734175 Cavia porcellus
100861217 Capra hircus
101115489 Ovis aries
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