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RFWD3 蛋白

(Ring Finger and WD Repeat Domain 3 (RFWD3))
E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.
RFWD3 Protein (AA 651-749) (GST tag) RFWD3 Protein (AA 651-749) (GST tag) RFWD3 Protein (AA 651-749) (GST tag) (ABIN1317874)

RFWD3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

RFWD3 Protein (AA 1-774) (His tag) RFWD3 Protein (AA 1-774) (His tag) RFWD3 Protein (AA 1-774) (His tag) (ABIN3094992)

Crystallography grade RFWD3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

RFWD3 Protein (AA 1-774) (His tag) RFWD3 Protein (AA 1-774) (His tag) RFWD3 Protein (AA 1-774) (His tag) (ABIN3136488)

Crystallography grade RFWD3 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

RFWD3 蛋白 by Grade

Find RFWD3 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

RFWD3 蛋白 by Origin

Find RFWD3 蛋白 for a variety of species such as anti-Human RFWD3, anti-Mouse RFWD3. The species listed below are among those available. Click on a link to go to the corresponding products.

RFWD3 蛋白 by Source

Here you will find RFWD3 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

RFWD3 蛋白 by 蛋白类型

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RFWD3 蛋白 by 应用范围

Find RFWD3 蛋白 validated for a specific application such as ELISA, WB, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular RFWD3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317874
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094992
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136488
Quantity 1 mg
Datasheet Datasheet

Aliases for RFWD3 蛋白

ring finger and WD repeat domain 3 (Rfwd3) 蛋白
ring finger and WD repeat domain 3 (RFWD3) 蛋白
BC027246 蛋白
RFWD3 蛋白
RGD1305243 蛋白
RNF201 蛋白
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